Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106736429> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2106736429 abstract "Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression that correspond to that specific pathogen. Venezuelan equine encephalitis (VEE) is a mosquito-borne viral disease characterized by fever and one or more of the following: severe headache, back pain, myalgias, prostration, chills, nausea, vomiting, weakness and other flu-like symptoms. Screening for host mRNA obtained from blood samples after exposure to VEEV may provide the means for early detection of surrogate markers of the impending illness and provide appropriate strategies for treatment.We have been carrying out gene expression analysis of PBMC exposed to VEEV to extract signatures and diagnostic markers of early exposure to be used in non invasive blood analysis methods. In this study, we used high throughput gene expression analysis to identify markers of early and late exposures to VEEV in vivo in Cynomolgus macaques (Macaca fascicularis). We carried out cDNA microarrays and real time PCR on blood samples obtained from the NHP model resulting in a panel of host genes that are altered in response to VEEV.Screening for host mRNA obtained from blood samples after exposure to VEEV may provide the means for early detection of surrogate markers of the impending illness and provide appropriate strategies for treatment." @default.
- W2106736429 created "2016-06-24" @default.
- W2106736429 creator A5004751787 @default.
- W2106736429 creator A5029401784 @default.
- W2106736429 creator A5043405281 @default.
- W2106736429 creator A5052765899 @default.
- W2106736429 creator A5065167357 @default.
- W2106736429 creator A5082731692 @default.
- W2106736429 date "2007-08-29" @default.
- W2106736429 modified "2023-10-14" @default.
- W2106736429 title "Blood genomic profiles of exposures to Venezuelan equine encephalitis in Cynomolgus macaques (Macaca fascicularis)" @default.
- W2106736429 cites W1526590030 @default.
- W2106736429 cites W1911019285 @default.
- W2106736429 cites W1971726382 @default.
- W2106736429 cites W1988176421 @default.
- W2106736429 cites W1997488521 @default.
- W2106736429 cites W2154444557 @default.
- W2106736429 cites W2184046950 @default.
- W2106736429 cites W2279913709 @default.
- W2106736429 cites W2404135330 @default.
- W2106736429 cites W4243163734 @default.
- W2106736429 doi "https://doi.org/10.1186/1743-422x-4-82" @default.
- W2106736429 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2042503" @default.
- W2106736429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17727720" @default.
- W2106736429 hasPublicationYear "2007" @default.
- W2106736429 type Work @default.
- W2106736429 sameAs 2106736429 @default.
- W2106736429 citedByCount "11" @default.
- W2106736429 countsByYear W21067364292012 @default.
- W2106736429 countsByYear W21067364292013 @default.
- W2106736429 countsByYear W21067364292016 @default.
- W2106736429 countsByYear W21067364292020 @default.
- W2106736429 crossrefType "journal-article" @default.
- W2106736429 hasAuthorship W2106736429A5004751787 @default.
- W2106736429 hasAuthorship W2106736429A5029401784 @default.
- W2106736429 hasAuthorship W2106736429A5043405281 @default.
- W2106736429 hasAuthorship W2106736429A5052765899 @default.
- W2106736429 hasAuthorship W2106736429A5065167357 @default.
- W2106736429 hasAuthorship W2106736429A5082731692 @default.
- W2106736429 hasBestOaLocation W21067364291 @default.
- W2106736429 hasConcept C104317684 @default.
- W2106736429 hasConcept C137061746 @default.
- W2106736429 hasConcept C159047783 @default.
- W2106736429 hasConcept C202751555 @default.
- W2106736429 hasConcept C203014093 @default.
- W2106736429 hasConcept C2522874641 @default.
- W2106736429 hasConcept C2777474056 @default.
- W2106736429 hasConcept C48023723 @default.
- W2106736429 hasConcept C54355233 @default.
- W2106736429 hasConcept C83455156 @default.
- W2106736429 hasConcept C86803240 @default.
- W2106736429 hasConceptScore W2106736429C104317684 @default.
- W2106736429 hasConceptScore W2106736429C137061746 @default.
- W2106736429 hasConceptScore W2106736429C159047783 @default.
- W2106736429 hasConceptScore W2106736429C202751555 @default.
- W2106736429 hasConceptScore W2106736429C203014093 @default.
- W2106736429 hasConceptScore W2106736429C2522874641 @default.
- W2106736429 hasConceptScore W2106736429C2777474056 @default.
- W2106736429 hasConceptScore W2106736429C48023723 @default.
- W2106736429 hasConceptScore W2106736429C54355233 @default.
- W2106736429 hasConceptScore W2106736429C83455156 @default.
- W2106736429 hasConceptScore W2106736429C86803240 @default.
- W2106736429 hasIssue "1" @default.
- W2106736429 hasLocation W21067364291 @default.
- W2106736429 hasLocation W21067364292 @default.
- W2106736429 hasLocation W21067364293 @default.
- W2106736429 hasLocation W21067364294 @default.
- W2106736429 hasOpenAccess W2106736429 @default.
- W2106736429 hasPrimaryLocation W21067364291 @default.
- W2106736429 hasRelatedWork W1452174070 @default.
- W2106736429 hasRelatedWork W165984422 @default.
- W2106736429 hasRelatedWork W2101415723 @default.
- W2106736429 hasRelatedWork W2136839725 @default.
- W2106736429 hasRelatedWork W2151363875 @default.
- W2106736429 hasRelatedWork W2412629351 @default.
- W2106736429 hasRelatedWork W2515588458 @default.
- W2106736429 hasRelatedWork W2553775999 @default.
- W2106736429 hasRelatedWork W3202986116 @default.
- W2106736429 hasRelatedWork W4280518054 @default.
- W2106736429 hasVolume "4" @default.
- W2106736429 isParatext "false" @default.
- W2106736429 isRetracted "false" @default.
- W2106736429 magId "2106736429" @default.
- W2106736429 workType "article" @default.