Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106743425> ?p ?o ?g. }
- W2106743425 endingPage "7758" @default.
- W2106743425 startingPage "7748" @default.
- W2106743425 abstract "Type IV pili are required for social gliding motility in Myxococcus xanthus. In this work, the expression of pilin (the pilA gene product) during vegetative growth and fruiting-body development was examined. A polyclonal antibody against the pilA gene product (prepilin) was prepared, along with a pilA-lacZ fusion, and was used to assay expression of pilA in M. xanthus in different mutant backgrounds. pilA expression required the response regulator pilR but was negatively regulated by the putative sensor kinase pilS. pilA expression did not require pilB, pilC, or pilT. pilA was also autoregulated; a mutation which altered an invariant glutamate five residues from the presumed prepilin processing site eliminated this autoregulation, as did a deletion of the pilA gene. Primer extension and S1 nuclease analysis identified a sigma54 promoter upstream of pilA, consistent with the homology of pilR to the NtrC family of response regulators. Expression of pilA was found to be developmentally regulated; however, the timing of this expression pattern was not entirely dependent on pilS or pilR. Finally, pilA expression was induced by high nutrient concentrations, an effect that was also not dependent on pilS or pilR." @default.
- W2106743425 created "2016-06-24" @default.
- W2106743425 creator A5019572514 @default.
- W2106743425 creator A5045011057 @default.
- W2106743425 date "1997-12-01" @default.
- W2106743425 modified "2023-10-18" @default.
- W2106743425 title "Regulation of expression of the pilA gene in Myxococcus xanthus" @default.
- W2106743425 cites W1551575172 @default.
- W2106743425 cites W1551654851 @default.
- W2106743425 cites W1556995445 @default.
- W2106743425 cites W1558407083 @default.
- W2106743425 cites W1563474996 @default.
- W2106743425 cites W1582323836 @default.
- W2106743425 cites W1585654488 @default.
- W2106743425 cites W1605808406 @default.
- W2106743425 cites W1607249005 @default.
- W2106743425 cites W1802201168 @default.
- W2106743425 cites W181760639 @default.
- W2106743425 cites W1845147287 @default.
- W2106743425 cites W1880457206 @default.
- W2106743425 cites W1936991984 @default.
- W2106743425 cites W1944538069 @default.
- W2106743425 cites W1952814327 @default.
- W2106743425 cites W1971584852 @default.
- W2106743425 cites W1975993749 @default.
- W2106743425 cites W1976281860 @default.
- W2106743425 cites W1980129303 @default.
- W2106743425 cites W1985941150 @default.
- W2106743425 cites W1988283355 @default.
- W2106743425 cites W1990258497 @default.
- W2106743425 cites W1993888732 @default.
- W2106743425 cites W1994921384 @default.
- W2106743425 cites W1997440166 @default.
- W2106743425 cites W2003729219 @default.
- W2106743425 cites W2007241669 @default.
- W2106743425 cites W2019140963 @default.
- W2106743425 cites W2019500447 @default.
- W2106743425 cites W2038663142 @default.
- W2106743425 cites W2040661576 @default.
- W2106743425 cites W2048205348 @default.
- W2106743425 cites W2051141334 @default.
- W2106743425 cites W2052480626 @default.
- W2106743425 cites W2054099099 @default.
- W2106743425 cites W2057785907 @default.
- W2106743425 cites W2063694547 @default.
- W2106743425 cites W2077020815 @default.
- W2106743425 cites W2081761697 @default.
- W2106743425 cites W2082730687 @default.
- W2106743425 cites W2098108206 @default.
- W2106743425 cites W2104820911 @default.
- W2106743425 cites W2108141139 @default.
- W2106743425 cites W2108405388 @default.
- W2106743425 cites W2110719101 @default.
- W2106743425 cites W2112522262 @default.
- W2106743425 cites W2116553413 @default.
- W2106743425 cites W2124584113 @default.
- W2106743425 cites W2127186235 @default.
- W2106743425 cites W2129874157 @default.
- W2106743425 cites W2134460102 @default.
- W2106743425 cites W2139906682 @default.
- W2106743425 cites W2142976427 @default.
- W2106743425 cites W2144052508 @default.
- W2106743425 cites W2148894818 @default.
- W2106743425 cites W2150515283 @default.
- W2106743425 cites W2155678213 @default.
- W2106743425 cites W2166648691 @default.
- W2106743425 cites W2180848182 @default.
- W2106743425 doi "https://doi.org/10.1128/jb.179.24.7748-7758.1997" @default.
- W2106743425 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/179738" @default.
- W2106743425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9401034" @default.
- W2106743425 hasPublicationYear "1997" @default.
- W2106743425 type Work @default.
- W2106743425 sameAs 2106743425 @default.
- W2106743425 citedByCount "190" @default.
- W2106743425 countsByYear W21067434252012 @default.
- W2106743425 countsByYear W21067434252013 @default.
- W2106743425 countsByYear W21067434252014 @default.
- W2106743425 countsByYear W21067434252015 @default.
- W2106743425 countsByYear W21067434252016 @default.
- W2106743425 countsByYear W21067434252017 @default.
- W2106743425 countsByYear W21067434252018 @default.
- W2106743425 countsByYear W21067434252019 @default.
- W2106743425 countsByYear W21067434252020 @default.
- W2106743425 countsByYear W21067434252021 @default.
- W2106743425 countsByYear W21067434252022 @default.
- W2106743425 countsByYear W21067434252023 @default.
- W2106743425 crossrefType "journal-article" @default.
- W2106743425 hasAuthorship W2106743425A5019572514 @default.
- W2106743425 hasAuthorship W2106743425A5045011057 @default.
- W2106743425 hasBestOaLocation W21067434251 @default.
- W2106743425 hasConcept C104317684 @default.
- W2106743425 hasConcept C143065580 @default.
- W2106743425 hasConcept C150194340 @default.
- W2106743425 hasConcept C165864922 @default.
- W2106743425 hasConcept C170344550 @default.
- W2106743425 hasConcept C174832134 @default.
- W2106743425 hasConcept C2776803919 @default.
- W2106743425 hasConcept C2777120639 @default.