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- W2106753727 endingPage "2748" @default.
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- W2106753727 abstract "Membrane proteins are synthesized and folded in the endoplasmic reticulum (ER), and continue their path to their site of residence along the secretory pathway. The COPII system has been identified as a key player for selecting and directing the fate of membrane and secretory cargo proteins. Selection of cargo proteins within the COPII vesicles is achieved by cargo receptors. The cornichon cargo receptor belongs to a conserved protein family found in eukaryotes that has been demonstrated to participate in the selection of integral membrane proteins as cargo for their correct targeting. Here it is demonstrated at the cellular level that rice cornichon OsCNIH1 interacts with OsHKT1;3 and, in yeast cells, enables the expression of the sodium transporter to the Golgi apparatus. Physical and functional HKT–cornichon interactions are confirmed by the mating-based split ubiquitin system, bimolecular fluorescence complementation, and Xenopus oocyte and yeast expression systems. The interaction between the two proteins occurs in the ER of plant cells and their co-expression in oocytes leads to the sequestration of the transporter in the ER. In the yeast cornichon mutant erv14, OsHKT1;3 is mistargeted, preventing the toxic effects of sodium transport in the cell observed in wild-type cells or in the erv14 mutant that co-expressed OsHKT1;3 with either OsCNIH1 or Erv14p. Identification and characterization of rice cornichon as a possible cargo receptor opens up the opportunity to improve our knowledge on membrane protein targeting in plant cells." @default.
- W2106753727 created "2016-06-24" @default.
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- W2106753727 date "2015-03-07" @default.
- W2106753727 modified "2023-10-12" @default.
- W2106753727 title "Identification of rice cornichon as a possible cargo receptor for the Golgi-localized sodium transporter OsHKT1;3" @default.
- W2106753727 cites W141200506 @default.
- W2106753727 cites W1488983618 @default.
- W2106753727 cites W1501819320 @default.
- W2106753727 cites W1501984876 @default.
- W2106753727 cites W1508132604 @default.
- W2106753727 cites W1595972325 @default.
- W2106753727 cites W1596554803 @default.
- W2106753727 cites W1679107673 @default.
- W2106753727 cites W1965136593 @default.
- W2106753727 cites W1974764801 @default.
- W2106753727 cites W1980939512 @default.
- W2106753727 cites W1984311414 @default.
- W2106753727 cites W1987021757 @default.
- W2106753727 cites W1987582551 @default.
- W2106753727 cites W1989835605 @default.
- W2106753727 cites W2001330685 @default.
- W2106753727 cites W2002894295 @default.
- W2106753727 cites W2003460583 @default.
- W2106753727 cites W2003954715 @default.
- W2106753727 cites W2005465545 @default.
- W2106753727 cites W2008149441 @default.
- W2106753727 cites W2009710499 @default.
- W2106753727 cites W2011727356 @default.
- W2106753727 cites W2022404904 @default.
- W2106753727 cites W2024222433 @default.
- W2106753727 cites W2025155265 @default.
- W2106753727 cites W2029983725 @default.
- W2106753727 cites W2035477608 @default.
- W2106753727 cites W2037185463 @default.
- W2106753727 cites W2037764683 @default.
- W2106753727 cites W2037944731 @default.
- W2106753727 cites W2041674095 @default.
- W2106753727 cites W2042717435 @default.
- W2106753727 cites W2045674449 @default.
- W2106753727 cites W2046014422 @default.
- W2106753727 cites W2046200067 @default.
- W2106753727 cites W2046332353 @default.
- W2106753727 cites W2049103997 @default.
- W2106753727 cites W2055034225 @default.
- W2106753727 cites W2056137161 @default.
- W2106753727 cites W2065314671 @default.
- W2106753727 cites W2065897005 @default.
- W2106753727 cites W2067026128 @default.
- W2106753727 cites W2068065147 @default.
- W2106753727 cites W2073303763 @default.
- W2106753727 cites W2075094914 @default.
- W2106753727 cites W2076883918 @default.
- W2106753727 cites W2077329481 @default.
- W2106753727 cites W2078868133 @default.
- W2106753727 cites W2082602413 @default.
- W2106753727 cites W2083720052 @default.
- W2106753727 cites W2098135399 @default.
- W2106753727 cites W2103590773 @default.
- W2106753727 cites W2103907401 @default.
- W2106753727 cites W2104909130 @default.
- W2106753727 cites W2109459831 @default.
- W2106753727 cites W2109944792 @default.
- W2106753727 cites W2109975639 @default.
- W2106753727 cites W2114908564 @default.
- W2106753727 cites W2115928499 @default.
- W2106753727 cites W2117938260 @default.
- W2106753727 cites W2118318984 @default.
- W2106753727 cites W2119556473 @default.
- W2106753727 cites W2120684043 @default.
- W2106753727 cites W2123144950 @default.
- W2106753727 cites W2123848559 @default.
- W2106753727 cites W2124733101 @default.
- W2106753727 cites W2125782175 @default.
- W2106753727 cites W2127417807 @default.
- W2106753727 cites W2132237896 @default.
- W2106753727 cites W2133464980 @default.
- W2106753727 cites W2135487705 @default.
- W2106753727 cites W2135843356 @default.
- W2106753727 cites W2137009674 @default.
- W2106753727 cites W2137078624 @default.
- W2106753727 cites W2139646081 @default.
- W2106753727 cites W2140107445 @default.
- W2106753727 cites W2143378459 @default.
- W2106753727 cites W2144799849 @default.
- W2106753727 cites W2150039733 @default.
- W2106753727 cites W2152472718 @default.
- W2106753727 cites W2154960162 @default.
- W2106753727 cites W2157309281 @default.