FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106756498> ?p ?o ?g. }

• W2106756498 endingPage "S254" @default.
• W2106756498 startingPage "S254" @default.
• W2106756498 abstract "Quality assurance (QA) in modern radiation therapy (RT) aims to detect inconsistencies that might adversely affect treatment outcome. A recent survey of 14 community cancer centers demonstrated uniform agreement on the importance of QA rounds, but significant variations in the proportion of curative cases being reviewed, as well as timing of such reviews. Another North American study reported that only 1% of its reviewed plans required modification; the type of tumor and fewer years of experience of the practicing radiation oncologist (RO) were the only variables associated with modifications. The objectives of the current study are to report the process and outcomes of our own breast QA rounds, and identify patient, tumor, or treatment factors that were associated with RT plan modifications. The current practice at our institution is that all curative-intent breast RT plans be presented at weekly QA rounds prior to commencement of RT (or within the first few fractions). Data were prospectively collected from all radical cases from January 1, 2010 to December 31, 2012; comments regarding the plan were documented in real-time. Descriptive statistics were utilized to determine the proportion of cases requiring no (A), minor (B), or major (C) modifications. Univariate and multivariate logistic regression and Cochran-Armitage trend test were applied to each variable. A total of 2223 breast QA cases were reviewed over this period; 47 cases (2.1%) underwent a minor change (B), and 52 cases (2.3%) required a major modification (C). The most common changes involved volume coverage, seroma contouring, addition of a boost, and the use of bolus. On univariate analysis, plans using more than 2 fields (OR = 2.57, p = 0.0011), triple negative disease (OR = 2.49, p = 0.017), axillary node dissection (OR = 1.76, p = 0.045), and tumor size more than 2 cm (OR = 2.01, p = 0.025) were significantly associated with category C. After multivariate analysis, only the number of fields (OR = 2.09, p = 0.017), and triple negative disease (OR = 2.34, p = 0.027) remained significant. No relationship was observed between experience of RO and plan modifications (B and C). An important observation related to patient cases that were node negative, margin negative, and 2 fields with no boost (n = 561), wherein modifications were required in only 0.89% of instances. It is feasible to conduct weekly QA review for all radically treated breast cancer cases prior to commencing RT in a busy cancer center. Radiation technique using more than 2 fields and triple negative disease predicted for a higher likelihood of plan modifications. Conversely, less than 1% of node-negative cases with negative surgical margins treated with a 2-field technique and no boost required adjustments. Predicting the probability of a radical breast RT plan requiring modifications will direct future re-structuring of QA rounds." @default.
• W2106756498 created "2016-06-24" @default.
• W2106756498 creator A5005287001 @default.
• W2106756498 creator A5009415342 @default.
• W2106756498 creator A5018452517 @default.
• W2106756498 creator A5034829322 @default.
• W2106756498 creator A5038140204 @default.
• W2106756498 creator A5044565573 @default.
• W2106756498 creator A5045287050 @default.
• W2106756498 creator A5052975576 @default.
• W2106756498 creator A5058619226 @default.
• W2106756498 creator A5062837724 @default.
• W2106756498 creator A5064571634 @default.
• W2106756498 creator A5070398961 @default.
• W2106756498 creator A5073354640 @default.
• W2106756498 creator A5080459908 @default.
• W2106756498 creator A5082234108 @default.
• W2106756498 creator A5085232447 @default.
• W2106756498 creator A5087324869 @default.
• W2106756498 date "2014-09-01" @default.
• W2106756498 modified "2023-10-16" @default.
• W2106756498 title "Predictors of Breast Radiation Therapy Plan Modifications: Quality Assurance Rounds in a Large Cancer Center" @default.
• W2106756498 cites W124456005 @default.
• W2106756498 cites W1484334610 @default.
• W2106756498 cites W1964009020 @default.
• W2106756498 cites W1965338587 @default.
• W2106756498 cites W1968731431 @default.
• W2106756498 cites W1969810738 @default.
• W2106756498 cites W1970483105 @default.
• W2106756498 cites W1982397919 @default.
• W2106756498 cites W1992704131 @default.
• W2106756498 cites W2005126609 @default.
• W2106756498 cites W2022564682 @default.
• W2106756498 cites W2032162832 @default.
• W2106756498 cites W2032856096 @default.
• W2106756498 cites W2054190773 @default.
• W2106756498 cites W2057717578 @default.
• W2106756498 cites W2059111914 @default.
• W2106756498 cites W2059237971 @default.
• W2106756498 cites W2089831776 @default.
• W2106756498 cites W2095182855 @default.
• W2106756498 cites W2100710834 @default.
• W2106756498 cites W2115588799 @default.
• W2106756498 cites W2115648664 @default.
• W2106756498 cites W2122773879 @default.
• W2106756498 cites W2128631638 @default.
• W2106756498 cites W2131537432 @default.
• W2106756498 cites W2139239770 @default.
• W2106756498 cites W2141031127 @default.
• W2106756498 cites W2145694984 @default.
• W2106756498 cites W2161501889 @default.
• W2106756498 cites W2163399589 @default.
• W2106756498 doi "https://doi.org/10.1016/j.ijrobp.2014.05.889" @default.
• W2106756498 hasPublicationYear "2014" @default.
• W2106756498 type Work @default.
• W2106756498 sameAs 2106756498 @default.
• W2106756498 citedByCount "0" @default.
• W2106756498 crossrefType "journal-article" @default.
• W2106756498 hasAuthorship W2106756498A5005287001 @default.
• W2106756498 hasAuthorship W2106756498A5009415342 @default.
• W2106756498 hasAuthorship W2106756498A5018452517 @default.
• W2106756498 hasAuthorship W2106756498A5034829322 @default.
• W2106756498 hasAuthorship W2106756498A5038140204 @default.
• W2106756498 hasAuthorship W2106756498A5044565573 @default.
• W2106756498 hasAuthorship W2106756498A5045287050 @default.
• W2106756498 hasAuthorship W2106756498A5052975576 @default.
• W2106756498 hasAuthorship W2106756498A5058619226 @default.
• W2106756498 hasAuthorship W2106756498A5062837724 @default.
• W2106756498 hasAuthorship W2106756498A5064571634 @default.
• W2106756498 hasAuthorship W2106756498A5070398961 @default.
• W2106756498 hasAuthorship W2106756498A5073354640 @default.
• W2106756498 hasAuthorship W2106756498A5080459908 @default.
• W2106756498 hasAuthorship W2106756498A5082234108 @default.
• W2106756498 hasAuthorship W2106756498A5085232447 @default.
• W2106756498 hasAuthorship W2106756498A5087324869 @default.
• W2106756498 hasBestOaLocation W21067564981 @default.
• W2106756498 hasConcept C106436119 @default.
• W2106756498 hasConcept C121608353 @default.
• W2106756498 hasConcept C126322002 @default.
• W2106756498 hasConcept C127413603 @default.
• W2106756498 hasConcept C141071460 @default.
• W2106756498 hasConcept C142724271 @default.
• W2106756498 hasConcept C144301174 @default.
• W2106756498 hasConcept C151956035 @default.
• W2106756498 hasConcept C19527891 @default.
• W2106756498 hasConcept C199639397 @default.
• W2106756498 hasConcept C2778618615 @default.
• W2106756498 hasConcept C2779104521 @default.
• W2106756498 hasConcept C2780920918 @default.
• W2106756498 hasConcept C38180746 @default.
• W2106756498 hasConcept C509974204 @default.
• W2106756498 hasConcept C530470458 @default.
• W2106756498 hasConcept C71924100 @default.
• W2106756498 hasConceptScore W2106756498C106436119 @default.
• W2106756498 hasConceptScore W2106756498C121608353 @default.
• W2106756498 hasConceptScore W2106756498C126322002 @default.
• W2106756498 hasConceptScore W2106756498C127413603 @default.
• W2106756498 hasConceptScore W2106756498C141071460 @default.

• next