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- W2106758077 abstract "No AccessJournal of UrologyAdult Urology1 Mar 2010Is Type 2 Diabetes Mellitus a Predictive Factor for Incontinence After Laparoscopic Radical Prostatectomy? A Matched Pair and Multivariate Analysis Dogu Teber, Mustafa Sofikerim, Mutlu Ates, Ali Serdar Gözen, Oguz Güven, Öner Sanli, and Jens Rassweiler Dogu TeberDogu Teber Department of Urology, SLK-Kliniken, University of Heidelberg, Heilbronn, Germany More articles by this author , Mustafa SofikerimMustafa Sofikerim Erciyes University Faculty of Medicine, Kayseri, Turkey More articles by this author , Mutlu AtesMutlu Ates Gülhane Military Medical Academy, Ankara, Turkey More articles by this author , Ali Serdar GözenAli Serdar Gözen Department of Urology, SLK-Kliniken, University of Heidelberg, Heilbronn, Germany More articles by this author , Oguz GüvenOguz Güven Mustafa Kemal University Faculty of Medicine, Hatay, Turkey More articles by this author , Öner SanliÖner Sanli Istanbul University Faculty of Medicine, Istanbul, Turkey More articles by this author , and Jens RassweilerJens Rassweiler Department of Urology, SLK-Kliniken, University of Heidelberg, Heilbronn, Germany More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2009.11.033AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated the effect of diabetes mellitus on incontinence after laparoscopic radical prostatectomy. Materials and Methods: From a series of 2,071 patients 135 with type 2 diabetes mellitus undergoing laparoscopic radical prostatectomy without radiotherapy and with a minimum followup of 24 months were identified. These patients were randomly matched with 135 nondiabetic controls for age, body mass index, preoperative prostate specific antigen, clinical stage, neoadjuvant hormonal therapy, prostate volume, previous surgery, surgeon skills, surgical approach, presence of bladder neck sparing, lymphadenectomy, technique of urethrovesical anastomosis and attempted nerve sparing surgery. Results: Using multivariate analysis age, diabetes mellitus and duration of diabetes mellitus were independent factors for post-prostatectomy incontinence in the whole group. Early continence (0 to 3 months) was observed in 43.7% of patients with diabetes and in 57.8% of nondiabetic controls which was statistically significant (p = 0.02). The rates of continence in patients with diabetes mellitus for 5 or more years at 3, 12 and 24-month evaluations were less than those in patients with diabetes mellitus for less than 5 years, and the difference was statistically significant (36% vs 50%, p = 0.001; 63.9% vs 82.4%, p = 0.02; 91.8% vs 98.6%, p = 0.03, respectively). Conclusions: Patients with type 2 diabetes mellitus need longer to recover continence than nondiabetics after laparoscopic radical prostatectomy. However, type II diabetes mellitus did not affect overall return to continence. Patients with diabetes mellitus for 5 or more years have an almost 5 times increased risk of post-prostatectomy incontinence compared to those with diabetes mellitus for less than 5 years. Diabetic patients should be counseled for the potential negative impact of diabetes mellitus on the recovery of continence after laparoscopic radical prostatectomy. 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Volume 183Issue 3March 2010Page: 1087-1091 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.Keywordsurinary incontinencediabetes mellituslaparoscopyprostatectomyMetricsAuthor Information Dogu Teber Department of Urology, SLK-Kliniken, University of Heidelberg, Heilbronn, Germany More articles by this author Mustafa Sofikerim Erciyes University Faculty of Medicine, Kayseri, Turkey More articles by this author Mutlu Ates Gülhane Military Medical Academy, Ankara, Turkey More articles by this author Ali Serdar Gözen Department of Urology, SLK-Kliniken, University of Heidelberg, Heilbronn, Germany More articles by this author Oguz Güven Mustafa Kemal University Faculty of Medicine, Hatay, Turkey More articles by this author Öner Sanli Istanbul University Faculty of Medicine, Istanbul, Turkey More articles by this author Jens Rassweiler Department of Urology, SLK-Kliniken, University of Heidelberg, Heilbronn, Germany More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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