Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106770196> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2106770196 endingPage "574" @default.
- W2106770196 startingPage "567" @default.
- W2106770196 abstract "Hydrogels of cross-linked poly (vinyl alcohol) (PVA) were developed and their properties were evaluated as a controlled-release oral solid dosage form. The concentration of glutaraldehyde involved in cross-linking is directly proportional to the compactness of the three-dimensional networks of the cross-linked PVA. The theoretical calculations reveal that the release of diltiazem HCl from PVA could be described by the combination of Fickian and diffusion-controlled models. The confirmation of cross-linking was done by differential scanning calorimetry and infrared spectroscopy. The microparticles show lower percentage compressibility but good flowability; hence a capsule dosage form was thought to be suitable. The toxicity level of PVA was confirmed to be 10 g/kg body weight. The microparticle formulation was optimized with respect to size distribution and increased drug loading. The microparticles were physically evaluated with respect to bulk density, angle of repose, and percent compressibility. The microparticles released a drug for 12 hr. The microparticles had a drug loading of 61% to 67%." @default.
- W2106770196 created "2016-06-24" @default.
- W2106770196 creator A5059894143 @default.
- W2106770196 creator A5060702005 @default.
- W2106770196 creator A5064648613 @default.
- W2106770196 date "1997-01-01" @default.
- W2106770196 modified "2023-10-16" @default.
- W2106770196 title "Development and Evaluation of Controlled-Release Diltiazem HCl Microparticles Using Cross-Linked Poly(Vinyl Alcohol)" @default.
- W2106770196 cites W1985796525 @default.
- W2106770196 cites W1989337976 @default.
- W2106770196 cites W2025801858 @default.
- W2106770196 cites W2061323050 @default.
- W2106770196 doi "https://doi.org/10.3109/03639049709149821" @default.
- W2106770196 hasPublicationYear "1997" @default.
- W2106770196 type Work @default.
- W2106770196 sameAs 2106770196 @default.
- W2106770196 citedByCount "105" @default.
- W2106770196 countsByYear W21067701962012 @default.
- W2106770196 countsByYear W21067701962013 @default.
- W2106770196 countsByYear W21067701962014 @default.
- W2106770196 countsByYear W21067701962015 @default.
- W2106770196 countsByYear W21067701962016 @default.
- W2106770196 countsByYear W21067701962017 @default.
- W2106770196 countsByYear W21067701962019 @default.
- W2106770196 countsByYear W21067701962020 @default.
- W2106770196 countsByYear W21067701962021 @default.
- W2106770196 countsByYear W21067701962022 @default.
- W2106770196 countsByYear W21067701962023 @default.
- W2106770196 crossrefType "journal-article" @default.
- W2106770196 hasAuthorship W2106770196A5059894143 @default.
- W2106770196 hasAuthorship W2106770196A5060702005 @default.
- W2106770196 hasAuthorship W2106770196A5064648613 @default.
- W2106770196 hasConcept C108586683 @default.
- W2106770196 hasConcept C121332964 @default.
- W2106770196 hasConcept C127413603 @default.
- W2106770196 hasConcept C151995515 @default.
- W2106770196 hasConcept C159985019 @default.
- W2106770196 hasConcept C163588942 @default.
- W2106770196 hasConcept C171250308 @default.
- W2106770196 hasConcept C178790620 @default.
- W2106770196 hasConcept C185592680 @default.
- W2106770196 hasConcept C188027245 @default.
- W2106770196 hasConcept C192562407 @default.
- W2106770196 hasConcept C2776741139 @default.
- W2106770196 hasConcept C2777521759 @default.
- W2106770196 hasConcept C2777529624 @default.
- W2106770196 hasConcept C2780666587 @default.
- W2106770196 hasConcept C2909111407 @default.
- W2106770196 hasConcept C39519442 @default.
- W2106770196 hasConcept C42360764 @default.
- W2106770196 hasConcept C43617362 @default.
- W2106770196 hasConcept C519063684 @default.
- W2106770196 hasConcept C521977710 @default.
- W2106770196 hasConcept C77281830 @default.
- W2106770196 hasConcept C97355855 @default.
- W2106770196 hasConceptScore W2106770196C108586683 @default.
- W2106770196 hasConceptScore W2106770196C121332964 @default.
- W2106770196 hasConceptScore W2106770196C127413603 @default.
- W2106770196 hasConceptScore W2106770196C151995515 @default.
- W2106770196 hasConceptScore W2106770196C159985019 @default.
- W2106770196 hasConceptScore W2106770196C163588942 @default.
- W2106770196 hasConceptScore W2106770196C171250308 @default.
- W2106770196 hasConceptScore W2106770196C178790620 @default.
- W2106770196 hasConceptScore W2106770196C185592680 @default.
- W2106770196 hasConceptScore W2106770196C188027245 @default.
- W2106770196 hasConceptScore W2106770196C192562407 @default.
- W2106770196 hasConceptScore W2106770196C2776741139 @default.
- W2106770196 hasConceptScore W2106770196C2777521759 @default.
- W2106770196 hasConceptScore W2106770196C2777529624 @default.
- W2106770196 hasConceptScore W2106770196C2780666587 @default.
- W2106770196 hasConceptScore W2106770196C2909111407 @default.
- W2106770196 hasConceptScore W2106770196C39519442 @default.
- W2106770196 hasConceptScore W2106770196C42360764 @default.
- W2106770196 hasConceptScore W2106770196C43617362 @default.
- W2106770196 hasConceptScore W2106770196C519063684 @default.
- W2106770196 hasConceptScore W2106770196C521977710 @default.
- W2106770196 hasConceptScore W2106770196C77281830 @default.
- W2106770196 hasConceptScore W2106770196C97355855 @default.
- W2106770196 hasIssue "6" @default.
- W2106770196 hasLocation W21067701961 @default.
- W2106770196 hasOpenAccess W2106770196 @default.
- W2106770196 hasPrimaryLocation W21067701961 @default.
- W2106770196 hasRelatedWork W1972346359 @default.
- W2106770196 hasRelatedWork W1973058058 @default.
- W2106770196 hasRelatedWork W1975968668 @default.
- W2106770196 hasRelatedWork W2026257869 @default.
- W2106770196 hasRelatedWork W2067933130 @default.
- W2106770196 hasRelatedWork W2143034786 @default.
- W2106770196 hasRelatedWork W2471938179 @default.
- W2106770196 hasRelatedWork W2597789968 @default.
- W2106770196 hasRelatedWork W2770683400 @default.
- W2106770196 hasRelatedWork W2980378647 @default.
- W2106770196 hasVolume "23" @default.
- W2106770196 isParatext "false" @default.
- W2106770196 isRetracted "false" @default.
- W2106770196 magId "2106770196" @default.
- W2106770196 workType "article" @default.