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• W2106819306 endingPage "1364" @default.
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• W2106819306 abstract "Raised lipoprotein(a) concentrations are considered to be a risk factor for atherothrombotic diseases. We examined whether baseline concentrations were a risk factor for an adverse outcome in patients admitted with acute coronary syndromes.Five hundred and nineteen patients admitted with suspected acute coronary syndromes were studied and followed prospectively for a median of 3 years. The prognostic significance of a baseline lipoprotein(a) concentration of > or = 30 mg x dl(-1) or lower for subsequent cardiac death was assessed in patients with myocardial infarction (266) and unstable angina (197) and compared with other variables in regression models. In patients with myocardial infarction, a baseline lipoprotein(a) concentration of > or =30 mg x dl(-1) was associated with a 62% increase in subsequent cardiac death compared to the lower concentration group (29.8% vs 18.6%, Log rank P=0.04). In a multivariate regression model a baseline lipoprotein(a) concentration of > or = 30 mg x dl(-1) retained its significance as an independent predictor of cardiac death (P=0.037). In patients with unstable angina, baseline concentrations of > or = 7.9 mg x dl(-1) were found to be significant predictors of cardiac death in univariate (P=0.021) and multivariate (P=0.035) regression models.Baseline lipoprotein(a) concentrations in patients admitted with acute coronary syndromes are associated with an increased risk of cardiac death. For patients with myocardial infarction a concentration of > or = 30 mg x dl(-1) appears appropriate as a risk discriminator; for patients admitted with unstable angina, however, much lower concentrations of lipoprotein(a) appear to be prognostically important." @default.
• W2106819306 created "2016-06-24" @default.
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• W2106819306 creator A5060324140 @default.
• W2106819306 creator A5085605849 @default.
• W2106819306 date "1998-09-01" @default.
• W2106819306 modified "2023-10-03" @default.
• W2106819306 title "Lipoprotein(a) as a risk predictor for cardiac mortality in patients with acute coronary syndromes" @default.
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• W2106819306 doi "https://doi.org/10.1053/euhj.1998.1043" @default.
• W2106819306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9792261" @default.
• W2106819306 hasPublicationYear "1998" @default.
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