Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106838448> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2106838448 endingPage "261" @default.
- W2106838448 startingPage "257" @default.
- W2106838448 abstract "Mast cell amines, platelet-activating factor (PAF), thromboxanes and leukotrienes have been shown to be released during nitric oxide-synthase inhibition in the rat intestine. Mast cells in rat isolated omentum (OMCs) or isolated from the rat peritoneal cavity (PMCs) have been used here to investigate the relationship(s) between these agents. N-nitro-L-arginine methyl ester (L-NAME, 100 μM) caused some degranulation of OMCs, but no enhancement of histamine release from PMCs. PAF (5 μM) and U46619 (1 μM) degranulated OMCs and enhanced histamine release from PMCs. Pre-treatment of the omentum with BN52021 (10 μM) inhibited degranulation of OMCs in response to L-NAME, PAF or U46619. Pretreatment with 1-benzylimidazole (5 or 50 μM) inhibited the effect of L-NAME but not that of PAF. Indomethacin (1 μM) or sodium nitroprusside (10 μM) also inhibited the effects of L-NAME, but nordihydroguaiaretic acid (30 μM) did not. In PMCs BN52021 inhibited PAF-induced, but not U46619-induced, release of histamine. These results suggest that inhibition of nitric oxidesynthase in the omentum by L-NAME allows thromboxanes to release PAF, which in turn degranulates and releases histamine from OMCs." @default.
- W2106838448 created "2016-06-24" @default.
- W2106838448 creator A5014214794 @default.
- W2106838448 creator A5051826015 @default.
- W2106838448 date "1996-01-01" @default.
- W2106838448 modified "2023-09-30" @default.
- W2106838448 title "Inhibition of NO-synthase and degranulation of rat omental mast cells in vitro" @default.
- W2106838448 doi "https://doi.org/10.1155/s0962935196000361" @default.
- W2106838448 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2365813" @default.
- W2106838448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18475736" @default.
- W2106838448 hasPublicationYear "1996" @default.
- W2106838448 type Work @default.
- W2106838448 sameAs 2106838448 @default.
- W2106838448 citedByCount "3" @default.
- W2106838448 countsByYear W21068384482023 @default.
- W2106838448 crossrefType "journal-article" @default.
- W2106838448 hasAuthorship W2106838448A5014214794 @default.
- W2106838448 hasAuthorship W2106838448A5051826015 @default.
- W2106838448 hasBestOaLocation W21068384481 @default.
- W2106838448 hasConcept C1122143 @default.
- W2106838448 hasConcept C126322002 @default.
- W2106838448 hasConcept C134018914 @default.
- W2106838448 hasConcept C170493617 @default.
- W2106838448 hasConcept C185592680 @default.
- W2106838448 hasConcept C2776042228 @default.
- W2106838448 hasConcept C2777622882 @default.
- W2106838448 hasConcept C2779020240 @default.
- W2106838448 hasConcept C2780571441 @default.
- W2106838448 hasConcept C49802076 @default.
- W2106838448 hasConcept C519581460 @default.
- W2106838448 hasConcept C55493867 @default.
- W2106838448 hasConcept C71924100 @default.
- W2106838448 hasConcept C86803240 @default.
- W2106838448 hasConcept C98274493 @default.
- W2106838448 hasConceptScore W2106838448C1122143 @default.
- W2106838448 hasConceptScore W2106838448C126322002 @default.
- W2106838448 hasConceptScore W2106838448C134018914 @default.
- W2106838448 hasConceptScore W2106838448C170493617 @default.
- W2106838448 hasConceptScore W2106838448C185592680 @default.
- W2106838448 hasConceptScore W2106838448C2776042228 @default.
- W2106838448 hasConceptScore W2106838448C2777622882 @default.
- W2106838448 hasConceptScore W2106838448C2779020240 @default.
- W2106838448 hasConceptScore W2106838448C2780571441 @default.
- W2106838448 hasConceptScore W2106838448C49802076 @default.
- W2106838448 hasConceptScore W2106838448C519581460 @default.
- W2106838448 hasConceptScore W2106838448C55493867 @default.
- W2106838448 hasConceptScore W2106838448C71924100 @default.
- W2106838448 hasConceptScore W2106838448C86803240 @default.
- W2106838448 hasConceptScore W2106838448C98274493 @default.
- W2106838448 hasIssue "4" @default.
- W2106838448 hasLocation W21068384481 @default.
- W2106838448 hasLocation W21068384482 @default.
- W2106838448 hasLocation W21068384483 @default.
- W2106838448 hasLocation W21068384484 @default.
- W2106838448 hasOpenAccess W2106838448 @default.
- W2106838448 hasPrimaryLocation W21068384481 @default.
- W2106838448 hasRelatedWork W1938121160 @default.
- W2106838448 hasRelatedWork W197673111 @default.
- W2106838448 hasRelatedWork W1979965990 @default.
- W2106838448 hasRelatedWork W1983315707 @default.
- W2106838448 hasRelatedWork W2000186658 @default.
- W2106838448 hasRelatedWork W2021303519 @default.
- W2106838448 hasRelatedWork W2025832885 @default.
- W2106838448 hasRelatedWork W2093916132 @default.
- W2106838448 hasRelatedWork W2106838448 @default.
- W2106838448 hasRelatedWork W2415590264 @default.
- W2106838448 hasVolume "5" @default.
- W2106838448 isParatext "false" @default.
- W2106838448 isRetracted "false" @default.
- W2106838448 magId "2106838448" @default.
- W2106838448 workType "article" @default.