FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106842975> ?p ?o ?g. }

• W2106842975 endingPage "6331" @default.
• W2106842975 startingPage "6325" @default.
• W2106842975 abstract "Mouse adenovirus type 1 (MAV-1) mutants with deletions of conserved regions of early region 1A (E1A) or with point mutations that eliminate translation of E1A were used to determine the role of E1A in MAV-1 replication. MAV-1 E1A mutants expressing no E1A protein grew to titers comparable to wild-type MAV-1 titers on mouse fibroblasts (3T6 fibroblasts and fibroblasts derived from Rb+/+, Rb+/-, and Rb-/- transgenic embryos). To test the hypothesis that E1A could induce a quiescent cell to reenter the cell cycle, fibroblasts were serum starved to stop DNA replication and cellular replication and then infected with the E1A mutant and wild-type viruses. All grew to equivalent titers. Steady-state levels of MAV-1 early mRNAs (E1A, E1B, E2, E3, and E4) from 3T6 cells infected with wild-type or E1A mutant virus were examined by Northern analysis. Steady-state levels of mRNAs from the mutant-infected cells were comparable to or greater than the levels found in wild-type virus infections for most of the early regions and for two late genes. The E2 mRNA levels were slightly reduced in all mutant infections relative to wild-type infections. E1A mRNA was not detected from infections with the MAV-1 E1A null mutant, pmE109, or from infections with similar MAV-1 E1A null mutants, pmE112 and pmE113. The implications for the lack of a requirement of E1A in cell culture are discussed." @default.
• W2106842975 created "2016-06-24" @default.
• W2106842975 creator A5004508225 @default.
• W2106842975 creator A5012570749 @default.
• W2106842975 creator A5033773798 @default.
• W2106842975 date "1998-08-01" @default.
• W2106842975 modified "2023-09-27" @default.
• W2106842975 title "Mouse Adenovirus Type 1 Early Region 1A Is Dispensable for Growth in Cultured Fibroblasts" @default.
• W2106842975 cites W1019447032 @default.
• W2106842975 cites W1484339355 @default.
• W2106842975 cites W1488940968 @default.
• W2106842975 cites W1489610462 @default.
• W2106842975 cites W1503003173 @default.
• W2106842975 cites W1522200518 @default.
• W2106842975 cites W1529032080 @default.
• W2106842975 cites W1542161618 @default.
• W2106842975 cites W1551802041 @default.
• W2106842975 cites W1587690029 @default.
• W2106842975 cites W1758747526 @default.
• W2106842975 cites W1762351857 @default.
• W2106842975 cites W1818730568 @default.
• W2106842975 cites W1830652552 @default.
• W2106842975 cites W1838547105 @default.
• W2106842975 cites W1869766858 @default.
• W2106842975 cites W1907299583 @default.
• W2106842975 cites W1911213431 @default.
• W2106842975 cites W1911649157 @default.
• W2106842975 cites W1917927191 @default.
• W2106842975 cites W1920231241 @default.
• W2106842975 cites W1926037744 @default.
• W2106842975 cites W1938755197 @default.
• W2106842975 cites W1967404701 @default.
• W2106842975 cites W1968219959 @default.
• W2106842975 cites W1971436037 @default.
• W2106842975 cites W1974584555 @default.
• W2106842975 cites W1978055329 @default.
• W2106842975 cites W1980807416 @default.
• W2106842975 cites W1982205026 @default.
• W2106842975 cites W1985526147 @default.
• W2106842975 cites W1987160102 @default.
• W2106842975 cites W1987975025 @default.
• W2106842975 cites W1999876280 @default.
• W2106842975 cites W2003424331 @default.
• W2106842975 cites W2018289835 @default.
• W2106842975 cites W2021026547 @default.
• W2106842975 cites W2026885676 @default.
• W2106842975 cites W2032258076 @default.
• W2106842975 cites W2040003193 @default.
• W2106842975 cites W2050795594 @default.
• W2106842975 cites W2055490337 @default.
• W2106842975 cites W2057058623 @default.
• W2106842975 cites W2058795593 @default.
• W2106842975 cites W2059953918 @default.
• W2106842975 cites W2063367127 @default.
• W2106842975 cites W2063798194 @default.
• W2106842975 cites W2065262709 @default.
• W2106842975 cites W2068972558 @default.
• W2106842975 cites W2069812292 @default.
• W2106842975 cites W2072581924 @default.
• W2106842975 cites W2078396346 @default.
• W2106842975 cites W2080582035 @default.
• W2106842975 cites W2083522684 @default.
• W2106842975 cites W2091766380 @default.
• W2106842975 cites W2094554969 @default.
• W2106842975 cites W2094807913 @default.
• W2106842975 cites W2096690760 @default.
• W2106842975 cites W2100837269 @default.
• W2106842975 cites W2102154746 @default.
• W2106842975 cites W2116951270 @default.
• W2106842975 cites W2124528320 @default.
• W2106842975 cites W2126948870 @default.
• W2106842975 cites W2127199932 @default.
• W2106842975 cites W2140089674 @default.
• W2106842975 cites W2144144425 @default.
• W2106842975 cites W2145312783 @default.
• W2106842975 cites W2146998438 @default.
• W2106842975 cites W2153176195 @default.
• W2106842975 cites W2155009866 @default.
• W2106842975 cites W2166329605 @default.
• W2106842975 cites W2443338041 @default.
• W2106842975 cites W2917803657 @default.
• W2106842975 cites W342448828 @default.
• W2106842975 cites W4229602207 @default.
• W2106842975 cites W4242346382 @default.
• W2106842975 cites W4242501310 @default.
• W2106842975 cites W4243071325 @default.
• W2106842975 cites W4244118502 @default.
• W2106842975 cites W4248919231 @default.
• W2106842975 cites W904109129 @default.
• W2106842975 doi "https://doi.org/10.1128/jvi.72.8.6325-6331.1998" @default.
• W2106842975 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/109774" @default.
• W2106842975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9658071" @default.
• W2106842975 hasPublicationYear "1998" @default.
• W2106842975 type Work @default.
• W2106842975 sameAs 2106842975 @default.
• W2106842975 citedByCount "13" @default.
• W2106842975 countsByYear W21068429752014 @default.
• W2106842975 countsByYear W21068429752016 @default.

• next