FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106912912> ?p ?o ?g. }

• W2106912912 endingPage "165" @default.
• W2106912912 startingPage "150" @default.
• W2106912912 abstract "The cellular and molecular study of dorsal neural tube ablation reported here demonstrates a critical role for midline closure in hindbrain repatterning. This was revealed by detailed analysis of the transcriptional response of two genes, Pax-3 and slug, during repair of the neural tube following ablation. The reexpression of Pax-3 appears to rely on a single surface ectoderm/neuroepithelial contact, while this is insufficient for reexpression of slug. In fact, slug up-regulation only occurred upon midline closure and, strikingly, corresponded to down-regulation of Pax-3. We examined whether a candidate dorsalizing molecule, Bmp-4, was responsible for this reciprocal regulation of Pax-3 and slug at midline closure. However, Bmp-4 was not reexpressed following ablation, indicating not only that it is not responsible for the observed repatterning but that it lies in regulatory pathways distinct from Pax-3 and slug. We additionally examined the expression of Pax-6, which, together with assessment of the pattern of cranial ganglia, roof plate morphology, and positioning of branchiomotor exit points, demonstrates that neural crest regeneration is accompanied by reestablishment of a normal dorsoventral pattern within the neural tube. Thus, both local and longer range patterning appears to be restored following ablation, which is reliant dorsally on midline closure of the neural tube." @default.
• W2106912912 created "2016-06-24" @default.
• W2106912912 creator A5000598610 @default.
• W2106912912 creator A5011748145 @default.
• W2106912912 creator A5034447135 @default.
• W2106912912 creator A5065445096 @default.
• W2106912912 date "1997-03-01" @default.
• W2106912912 modified "2023-10-18" @default.
• W2106912912 title "A Role for Midline Closure in the Reestablishment of Dorsoventral Pattern Following Dorsal Hindbrain Ablation" @default.
• W2106912912 cites W1911954838 @default.
• W2106912912 cites W1972255525 @default.
• W2106912912 cites W1985876982 @default.
• W2106912912 cites W1989685638 @default.
• W2106912912 cites W1994351488 @default.
• W2106912912 cites W2006417453 @default.
• W2106912912 cites W2009806996 @default.
• W2106912912 cites W2016686483 @default.
• W2106912912 cites W2030447376 @default.
• W2106912912 cites W2040773128 @default.
• W2106912912 cites W2048020747 @default.
• W2106912912 cites W2048083836 @default.
• W2106912912 cites W2053504519 @default.
• W2106912912 cites W2065200502 @default.
• W2106912912 cites W2069957508 @default.
• W2106912912 cites W2072325944 @default.
• W2106912912 cites W2079230542 @default.
• W2106912912 cites W2091223115 @default.
• W2106912912 cites W2096548029 @default.
• W2106912912 cites W2115164560 @default.
• W2106912912 cites W2139203676 @default.
• W2106912912 cites W2140034535 @default.
• W2106912912 cites W2149913475 @default.
• W2106912912 cites W2164682485 @default.
• W2106912912 cites W2385672755 @default.
• W2106912912 cites W2416447723 @default.
• W2106912912 cites W4243652998 @default.
• W2106912912 doi "https://doi.org/10.1006/dbio.1996.8460" @default.
• W2106912912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9126291" @default.
• W2106912912 hasPublicationYear "1997" @default.
• W2106912912 type Work @default.
• W2106912912 sameAs 2106912912 @default.
• W2106912912 citedByCount "21" @default.
• W2106912912 countsByYear W21069129122012 @default.
• W2106912912 crossrefType "journal-article" @default.
• W2106912912 hasAuthorship W2106912912A5000598610 @default.
• W2106912912 hasAuthorship W2106912912A5011748145 @default.
• W2106912912 hasAuthorship W2106912912A5034447135 @default.
• W2106912912 hasAuthorship W2106912912A5065445096 @default.
• W2106912912 hasBestOaLocation W21069129121 @default.
• W2106912912 hasConcept C103607123 @default.
• W2106912912 hasConcept C104317684 @default.
• W2106912912 hasConcept C105702510 @default.
• W2106912912 hasConcept C121587040 @default.
• W2106912912 hasConcept C126322002 @default.
• W2106912912 hasConcept C136834591 @default.
• W2106912912 hasConcept C150194340 @default.
• W2106912912 hasConcept C169760540 @default.
• W2106912912 hasConcept C196843134 @default.
• W2106912912 hasConcept C197849852 @default.
• W2106912912 hasConcept C200707615 @default.
• W2106912912 hasConcept C2777075493 @default.
• W2106912912 hasConcept C2778902805 @default.
• W2106912912 hasConcept C2779329299 @default.
• W2106912912 hasConcept C2780594696 @default.
• W2106912912 hasConcept C2781381752 @default.
• W2106912912 hasConcept C28328180 @default.
• W2106912912 hasConcept C502942594 @default.
• W2106912912 hasConcept C54355233 @default.
• W2106912912 hasConcept C64632358 @default.
• W2106912912 hasConcept C71924100 @default.
• W2106912912 hasConcept C86803240 @default.
• W2106912912 hasConcept C87073359 @default.
• W2106912912 hasConcept C95444343 @default.
• W2106912912 hasConceptScore W2106912912C103607123 @default.
• W2106912912 hasConceptScore W2106912912C104317684 @default.
• W2106912912 hasConceptScore W2106912912C105702510 @default.
• W2106912912 hasConceptScore W2106912912C121587040 @default.
• W2106912912 hasConceptScore W2106912912C126322002 @default.
• W2106912912 hasConceptScore W2106912912C136834591 @default.
• W2106912912 hasConceptScore W2106912912C150194340 @default.
• W2106912912 hasConceptScore W2106912912C169760540 @default.
• W2106912912 hasConceptScore W2106912912C196843134 @default.
• W2106912912 hasConceptScore W2106912912C197849852 @default.
• W2106912912 hasConceptScore W2106912912C200707615 @default.
• W2106912912 hasConceptScore W2106912912C2777075493 @default.
• W2106912912 hasConceptScore W2106912912C2778902805 @default.
• W2106912912 hasConceptScore W2106912912C2779329299 @default.
• W2106912912 hasConceptScore W2106912912C2780594696 @default.
• W2106912912 hasConceptScore W2106912912C2781381752 @default.
• W2106912912 hasConceptScore W2106912912C28328180 @default.
• W2106912912 hasConceptScore W2106912912C502942594 @default.
• W2106912912 hasConceptScore W2106912912C54355233 @default.
• W2106912912 hasConceptScore W2106912912C64632358 @default.
• W2106912912 hasConceptScore W2106912912C71924100 @default.
• W2106912912 hasConceptScore W2106912912C86803240 @default.
• W2106912912 hasConceptScore W2106912912C87073359 @default.
• W2106912912 hasConceptScore W2106912912C95444343 @default.
• W2106912912 hasIssue "2" @default.

• next