FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106919150> ?p ?o ?g. }

• W2106919150 endingPage "1292" @default.
• W2106919150 startingPage "1285" @default.
• W2106919150 abstract "Obesity has been suggested to be a low-grade systemic inflammatory state, therefore we studied the interaction between human adipocytes and monocytes via adipose tissue (AT)-derived capillary endothelium. Cells composing the stroma-vascular fraction (SVF) of human ATs were characterized by fluorescence-activated cell sorter (FACS) analysis and two cell subsets (resident macrophages and endothelial cells [ECs]) were isolated using antibody-coupled microbeads. Media conditioned by mature adipocytes maintained in fibrin gels were applied to AT-derived ECs. Thereafter, the expression of endothelial adhesion molecules was analyzed as well as the adhesion and transmigration of human monocytes. FACS analysis showed that 11% of the SVF is composed of CD14+/CD31+ cells, characterized as resident macrophages. A positive correlation was found between the BMI and the percentage of resident macrophages, suggesting that fat tissue growth is associated with a recruitment of blood monocytes. Incubation of AT-derived ECs with adipocyte-conditioned medium resulted in the upregulation of EC adhesion molecules and the increased chemotaxis of blood monocytes, an effect mimicked by recombinant human leptin. These results indicate that adipokines, such as leptin, activate ECs, leading to an enhanced diapedesis of blood monocytes, and suggesting that fat mass growth might be linked to inflammatory processes." @default.
• W2106919150 created "2016-06-24" @default.
• W2106919150 creator A5034498244 @default.
• W2106919150 creator A5046458986 @default.
• W2106919150 creator A5050471583 @default.
• W2106919150 creator A5058047255 @default.
• W2106919150 creator A5058587113 @default.
• W2106919150 creator A5090462051 @default.
• W2106919150 creator A5091400495 @default.
• W2106919150 date "2004-05-01" @default.
• W2106919150 modified "2023-10-11" @default.
• W2106919150 title "From Blood Monocytes to Adipose Tissue-Resident Macrophages" @default.
• W2106919150 cites W1531394161 @default.
• W2106919150 cites W1606650298 @default.
• W2106919150 cites W1898391394 @default.
• W2106919150 cites W1981444005 @default.
• W2106919150 cites W1986841296 @default.
• W2106919150 cites W1992393383 @default.
• W2106919150 cites W1999067029 @default.
• W2106919150 cites W1999239339 @default.
• W2106919150 cites W1999771650 @default.
• W2106919150 cites W2019960170 @default.
• W2106919150 cites W2027530704 @default.
• W2106919150 cites W2050726791 @default.
• W2106919150 cites W2059511498 @default.
• W2106919150 cites W2079793296 @default.
• W2106919150 cites W2089581497 @default.
• W2106919150 cites W2089783517 @default.
• W2106919150 cites W2096216712 @default.
• W2106919150 cites W2096599017 @default.
• W2106919150 cites W2097849868 @default.
• W2106919150 cites W2119316150 @default.
• W2106919150 cites W2125302795 @default.
• W2106919150 cites W2147846101 @default.
• W2106919150 cites W2148896219 @default.
• W2106919150 cites W2149672568 @default.
• W2106919150 cites W2154753838 @default.
• W2106919150 cites W2156658448 @default.
• W2106919150 cites W2165139442 @default.
• W2106919150 cites W4238497443 @default.
• W2106919150 cites W4238544378 @default.
• W2106919150 cites W4249727000 @default.
• W2106919150 doi "https://doi.org/10.2337/diabetes.53.5.1285" @default.
• W2106919150 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15111498" @default.
• W2106919150 hasPublicationYear "2004" @default.
• W2106919150 type Work @default.
• W2106919150 sameAs 2106919150 @default.
• W2106919150 citedByCount "561" @default.
• W2106919150 countsByYear W21069191502012 @default.
• W2106919150 countsByYear W21069191502013 @default.
• W2106919150 countsByYear W21069191502014 @default.
• W2106919150 countsByYear W21069191502015 @default.
• W2106919150 countsByYear W21069191502016 @default.
• W2106919150 countsByYear W21069191502017 @default.
• W2106919150 countsByYear W21069191502018 @default.
• W2106919150 countsByYear W21069191502019 @default.
• W2106919150 countsByYear W21069191502020 @default.
• W2106919150 countsByYear W21069191502021 @default.
• W2106919150 countsByYear W21069191502022 @default.
• W2106919150 countsByYear W21069191502023 @default.
• W2106919150 crossrefType "journal-article" @default.
• W2106919150 hasAuthorship W2106919150A5034498244 @default.
• W2106919150 hasAuthorship W2106919150A5046458986 @default.
• W2106919150 hasAuthorship W2106919150A5050471583 @default.
• W2106919150 hasAuthorship W2106919150A5058047255 @default.
• W2106919150 hasAuthorship W2106919150A5058587113 @default.
• W2106919150 hasAuthorship W2106919150A5090462051 @default.
• W2106919150 hasAuthorship W2106919150A5091400495 @default.
• W2106919150 hasBestOaLocation W21069191501 @default.
• W2106919150 hasConcept C126322002 @default.
• W2106919150 hasConcept C134018914 @default.
• W2106919150 hasConcept C151955695 @default.
• W2106919150 hasConcept C16224149 @default.
• W2106919150 hasConcept C170493617 @default.
• W2106919150 hasConcept C171089720 @default.
• W2106919150 hasConcept C17675752 @default.
• W2106919150 hasConcept C185592680 @default.
• W2106919150 hasConcept C194832188 @default.
• W2106919150 hasConcept C202751555 @default.
• W2106919150 hasConcept C203014093 @default.
• W2106919150 hasConcept C2776175234 @default.
• W2106919150 hasConcept C2776914184 @default.
• W2106919150 hasConcept C2776992346 @default.
• W2106919150 hasConcept C2778513237 @default.
• W2106919150 hasConcept C2779244956 @default.
• W2106919150 hasConcept C2780613262 @default.
• W2106919150 hasConcept C2780745355 @default.
• W2106919150 hasConcept C2781184567 @default.
• W2106919150 hasConcept C511355011 @default.
• W2106919150 hasConcept C54166955 @default.
• W2106919150 hasConcept C553184892 @default.
• W2106919150 hasConcept C55493867 @default.
• W2106919150 hasConcept C71924100 @default.
• W2106919150 hasConcept C86803240 @default.
• W2106919150 hasConcept C95444343 @default.
• W2106919150 hasConceptScore W2106919150C126322002 @default.
• W2106919150 hasConceptScore W2106919150C134018914 @default.
• W2106919150 hasConceptScore W2106919150C151955695 @default.

• next