FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106936194> ?p ?o ?g. }

• W2106936194 endingPage "265" @default.
• W2106936194 startingPage "256" @default.
• W2106936194 abstract "The percentage of reduced coenzyme Q(10) (CoQ(10)H(2)) in total coenzyme Q(10) (TQ(10)) is decreased in plasma of patients with prematurity, hyperlipidemia, and liver disease. CoQ(10)H(2) is, however, easily oxidized and difficult to measure, and therefore reliable quantification of plasma CoQ(10)H(2) is of clinical importance.Venous blood was collected into evacuated tubes containing heparin, which were immediately placed on ice and promptly centrifuged at 4 degrees C. The plasma was harvested and stored in screw-top polypropylene tubes at -80 degrees C until analysis. After extraction with 1-propanol and centrifugation, the supernatant was injected directly into an HPLC system with coulometric detection.The in-line reduction procedure permitted transformation of CoQ(10) into CoQ(10)H(2) and avoided artifactual oxidation of CoQ(10)H(2). The electrochemical reduction yielded 99% CoQ(10)H(2). Only 100 microL of plasma was required to simultaneously measure CoQ(10)H(2) and CoQ(10) over an analytical range of 10 microg/L to 4 mg/L. Intra- and interassay CVs for CoQ(10) in human plasma were 1.2-4.9% across this range. Analytical recoveries were 95.8-101.0%. The percentage of CoQ(10)H(2) in TQ(10) was approximately 96% in apparently healthy individuals. The method allowed analysis of up to 40 samples within an 8-h period.This optimized method for CoQ(10)H(2) analysis provides rapid and precise results with the potential for high throughput. This method is specific and sufficiently sensitive for use in both clinical and research laboratories." @default.
• W2106936194 created "2016-06-24" @default.
• W2106936194 creator A5019154790 @default.
• W2106936194 creator A5019341812 @default.
• W2106936194 creator A5054586325 @default.
• W2106936194 creator A5064917718 @default.
• W2106936194 creator A5076542952 @default.
• W2106936194 date "2001-02-01" @default.
• W2106936194 modified "2023-10-06" @default.
• W2106936194 title "HPLC Analysis of Reduced and Oxidized Coenzyme Q10 in Human Plasma" @default.
• W2106936194 cites W1438668346 @default.
• W2106936194 cites W1961531184 @default.
• W2106936194 cites W1965621099 @default.
• W2106936194 cites W1969512437 @default.
• W2106936194 cites W1983421623 @default.
• W2106936194 cites W1993308019 @default.
• W2106936194 cites W2004675210 @default.
• W2106936194 cites W2015716483 @default.
• W2106936194 cites W2023381396 @default.
• W2106936194 cites W2033819095 @default.
• W2106936194 cites W2034277702 @default.
• W2106936194 cites W2036843014 @default.
• W2106936194 cites W2045662195 @default.
• W2106936194 cites W2049338320 @default.
• W2106936194 cites W2054389625 @default.
• W2106936194 cites W2063503610 @default.
• W2106936194 cites W2074384724 @default.
• W2106936194 cites W2083259478 @default.
• W2106936194 cites W2088522264 @default.
• W2106936194 cites W2114700007 @default.
• W2106936194 cites W2134341096 @default.
• W2106936194 cites W2137672734 @default.
• W2106936194 cites W2153636008 @default.
• W2106936194 cites W2164156793 @default.
• W2106936194 cites W2169723026 @default.
• W2106936194 cites W2325331402 @default.
• W2106936194 doi "https://doi.org/10.1093/clinchem/47.2.256" @default.
• W2106936194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11159774" @default.
• W2106936194 hasPublicationYear "2001" @default.
• W2106936194 type Work @default.
• W2106936194 sameAs 2106936194 @default.
• W2106936194 citedByCount "148" @default.
• W2106936194 countsByYear W21069361942012 @default.
• W2106936194 countsByYear W21069361942013 @default.
• W2106936194 countsByYear W21069361942014 @default.
• W2106936194 countsByYear W21069361942015 @default.
• W2106936194 countsByYear W21069361942016 @default.
• W2106936194 countsByYear W21069361942017 @default.
• W2106936194 countsByYear W21069361942018 @default.
• W2106936194 countsByYear W21069361942019 @default.
• W2106936194 countsByYear W21069361942020 @default.
• W2106936194 countsByYear W21069361942021 @default.
• W2106936194 countsByYear W21069361942022 @default.
• W2106936194 crossrefType "journal-article" @default.
• W2106936194 hasAuthorship W2106936194A5019154790 @default.
• W2106936194 hasAuthorship W2106936194A5019341812 @default.
• W2106936194 hasAuthorship W2106936194A5054586325 @default.
• W2106936194 hasAuthorship W2106936194A5064917718 @default.
• W2106936194 hasAuthorship W2106936194A5076542952 @default.
• W2106936194 hasBestOaLocation W21069361941 @default.
• W2106936194 hasConcept C14471203 @default.
• W2106936194 hasConcept C179998833 @default.
• W2106936194 hasConcept C185592680 @default.
• W2106936194 hasConcept C2779384338 @default.
• W2106936194 hasConcept C28859421 @default.
• W2106936194 hasConcept C29311851 @default.
• W2106936194 hasConcept C3020134792 @default.
• W2106936194 hasConcept C43617362 @default.
• W2106936194 hasConcept C55493867 @default.
• W2106936194 hasConcept C95986675 @default.
• W2106936194 hasConceptScore W2106936194C14471203 @default.
• W2106936194 hasConceptScore W2106936194C179998833 @default.
• W2106936194 hasConceptScore W2106936194C185592680 @default.
• W2106936194 hasConceptScore W2106936194C2779384338 @default.
• W2106936194 hasConceptScore W2106936194C28859421 @default.
• W2106936194 hasConceptScore W2106936194C29311851 @default.
• W2106936194 hasConceptScore W2106936194C3020134792 @default.
• W2106936194 hasConceptScore W2106936194C43617362 @default.
• W2106936194 hasConceptScore W2106936194C55493867 @default.
• W2106936194 hasConceptScore W2106936194C95986675 @default.
• W2106936194 hasIssue "2" @default.
• W2106936194 hasLocation W21069361941 @default.
• W2106936194 hasLocation W21069361942 @default.
• W2106936194 hasOpenAccess W2106936194 @default.
• W2106936194 hasPrimaryLocation W21069361941 @default.
• W2106936194 hasRelatedWork W1571248236 @default.
• W2106936194 hasRelatedWork W1969164368 @default.
• W2106936194 hasRelatedWork W1983508766 @default.
• W2106936194 hasRelatedWork W2026449451 @default.
• W2106936194 hasRelatedWork W2036400894 @default.
• W2106936194 hasRelatedWork W2049201081 @default.
• W2106936194 hasRelatedWork W2075754794 @default.
• W2106936194 hasRelatedWork W2096641431 @default.
• W2106936194 hasRelatedWork W2143157021 @default.
• W2106936194 hasRelatedWork W772560632 @default.
• W2106936194 hasVolume "47" @default.
• W2106936194 isParatext "false" @default.
• W2106936194 isRetracted "false" @default.

• next