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• W2107029558 abstract "Abstract Background Pain is common in head and neck cancer (HNC) patients and may be attributed to the malignancy and/or cancer treatment. Pain mechanisms and patient report of pain in HNC are expected to include both nociceptive and neuropathic components. The purpose of this study was to assess the trajectory of orofacial and other pain during and following treatment, using patient reports of neuropathic pain and nociceptive pain and pain impact. Methods 124 consecutive HNC patients receiving radiation therapy (RT) (95 men, 29 women; mean age: 54.7 ± 12.3 years) participated in a patient-reported outcome (PRO) assessment. Patients completed the McGill Pain Questionnaire three times during therapy and 3 months following study entry. Results The majority of patients related their pain to the tumor and/or cancer treatment. Whereas 59% reported their pain to be less severe than they expected, 29% were not satisfied with their level of pain despite pain management during cancer therapy. Worst pain was 3.0 ± 1.3 on a 0- to 5-point verbal descriptor scale. Pain intensity was present at entry, highest at 2-week follow-up, declining towards the end of treatment and persisting at 3-month follow-up. The most common neuropathic pain descriptors chosen were aching (20%) and burning (27%); nociceptive words chosen were dull (22%), sore (32%), tender (35%), and throbbing (23%), and affective/evaluative descriptors were tiring (25%) and annoying (41%). 57% of patients reported continuous pain, and combined continuous and intermittent pain was reported by 79% of patients. Discussion This study provides evidence that patients with HNC experience nociceptive and neuropathic pain during RT despite ongoing pain management. The affective and evaluative descriptors chosen for head and neck pain indicate considerable impact on quality of life even with low to moderate levels of pain intensity. These findings suggest that clinicians should consider contemporary management for both nociceptive and neuropathic pain in head and neck cancer patients." @default.
• W2107029558 created "2016-06-24" @default.
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• W2107029558 date "2009-07-14" @default.
• W2107029558 modified "2023-10-09" @default.
• W2107029558 title "Neuropathic and nociceptive pain in head and neck cancer patients receiving radiation therapy" @default.
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• W2107029558 doi "https://doi.org/10.1186/1758-3284-1-26" @default.
• W2107029558 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2717963" @default.
• W2107029558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19594943" @default.
• W2107029558 hasPublicationYear "2009" @default.
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