FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107029656> ?p ?o ?g. }

• W2107029656 endingPage "23" @default.
• W2107029656 startingPage "17" @default.
• W2107029656 abstract "Artemisinic aldehyde Δ11 (13) reductase (DBR2) is the checkpoint enzyme catalyzing artemisinic aldehyde to form dihydroartemisinic aldehyde directly involved in artemisinin biosynthetic pathway. In the present study, DBR2 was employed to engineer the biosynthetic pathway of artemisinin in transgenic plants of Artemisia annua L. Seven independent transgenic plants of A. annua with DBR2 overexpression driven by the cauliflower mosaic virus 35S promoter were obtained by Agrobacterium-mediated genetic transformation and confirmed by genomic PCR. The results of real-time qPCR analysis showed that the expression levels of DBR2 gene in all the seven transgenic lines were significantly higher than in nontransgenic control. The high-performance liquid chromatography analysis of artemisinin and its relative metabolites demonstrated that the contents of artemisinin and its direct precursor dihydroartemisinic acid were remarkably increased in the transgenic plants of A. annua with DBR2 overexpression. Interestingly, it was also found that the contents of arteannuin B and its direct precursor artemisinic acid in the branch pathway competing against artemisinin biosynthesis were also improved in DBR2-overexpressed A. annua plants. The transgenic results in the present study indicated that DBR2 is a useful structural gene in engineering the artemisinin biosynthetic pathway to develop genetically modified A. annua with the higher yield of artemisinin." @default.
• W2107029656 created "2016-06-24" @default.
• W2107029656 creator A5011156551 @default.
• W2107029656 creator A5011540763 @default.
• W2107029656 creator A5012718640 @default.
• W2107029656 creator A5021333738 @default.
• W2107029656 creator A5026295078 @default.
• W2107029656 creator A5030863883 @default.
• W2107029656 creator A5036800142 @default.
• W2107029656 creator A5076096328 @default.
• W2107029656 creator A5082045824 @default.
• W2107029656 date "2014-07-07" @default.
• W2107029656 modified "2023-10-09" @default.
• W2107029656 title "Overexpression of artemisinic aldehyde Δ11 (13) reductase gene-enhanced artemisinin and its relative metabolite biosynthesis in transgenic<i>Artemisia annua</i>L." @default.
• W2107029656 cites W1828295543 @default.
• W2107029656 cites W1969962785 @default.
• W2107029656 cites W1981404580 @default.
• W2107029656 cites W1984156348 @default.
• W2107029656 cites W1992324215 @default.
• W2107029656 cites W1992733039 @default.
• W2107029656 cites W2033812623 @default.
• W2107029656 cites W2034553168 @default.
• W2107029656 cites W2041671544 @default.
• W2107029656 cites W2049477468 @default.
• W2107029656 cites W2050000402 @default.
• W2107029656 cites W2050652584 @default.
• W2107029656 cites W2052269448 @default.
• W2107029656 cites W2057823601 @default.
• W2107029656 cites W2059889045 @default.
• W2107029656 cites W2071924031 @default.
• W2107029656 cites W2075579534 @default.
• W2107029656 cites W2083945129 @default.
• W2107029656 cites W2094333425 @default.
• W2107029656 cites W2096481443 @default.
• W2107029656 cites W2104903380 @default.
• W2107029656 cites W2108488573 @default.
• W2107029656 cites W2129447528 @default.
• W2107029656 cites W2146451828 @default.
• W2107029656 cites W2149202606 @default.
• W2107029656 cites W2152443621 @default.
• W2107029656 cites W4234457544 @default.
• W2107029656 doi "https://doi.org/10.1002/bab.1234" @default.
• W2107029656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25040292" @default.
• W2107029656 hasPublicationYear "2014" @default.
• W2107029656 type Work @default.
• W2107029656 sameAs 2107029656 @default.
• W2107029656 citedByCount "33" @default.
• W2107029656 countsByYear W21070296562015 @default.
• W2107029656 countsByYear W21070296562016 @default.
• W2107029656 countsByYear W21070296562017 @default.
• W2107029656 countsByYear W21070296562018 @default.
• W2107029656 countsByYear W21070296562019 @default.
• W2107029656 countsByYear W21070296562020 @default.
• W2107029656 countsByYear W21070296562021 @default.
• W2107029656 countsByYear W21070296562022 @default.
• W2107029656 countsByYear W21070296562023 @default.
• W2107029656 crossrefType "journal-article" @default.
• W2107029656 hasAuthorship W2107029656A5011156551 @default.
• W2107029656 hasAuthorship W2107029656A5011540763 @default.
• W2107029656 hasAuthorship W2107029656A5012718640 @default.
• W2107029656 hasAuthorship W2107029656A5021333738 @default.
• W2107029656 hasAuthorship W2107029656A5026295078 @default.
• W2107029656 hasAuthorship W2107029656A5030863883 @default.
• W2107029656 hasAuthorship W2107029656A5036800142 @default.
• W2107029656 hasAuthorship W2107029656A5076096328 @default.
• W2107029656 hasAuthorship W2107029656A5082045824 @default.
• W2107029656 hasConcept C102230213 @default.
• W2107029656 hasConcept C104317684 @default.
• W2107029656 hasConcept C122172344 @default.
• W2107029656 hasConcept C134651460 @default.
• W2107029656 hasConcept C181199279 @default.
• W2107029656 hasConcept C185592680 @default.
• W2107029656 hasConcept C203014093 @default.
• W2107029656 hasConcept C204241405 @default.
• W2107029656 hasConcept C2776120307 @default.
• W2107029656 hasConcept C2778048844 @default.
• W2107029656 hasConcept C2778371730 @default.
• W2107029656 hasConcept C2779691961 @default.
• W2107029656 hasConcept C553450214 @default.
• W2107029656 hasConcept C55493867 @default.
• W2107029656 hasConcept C6350086 @default.
• W2107029656 hasConcept C86803240 @default.
• W2107029656 hasConceptScore W2107029656C102230213 @default.
• W2107029656 hasConceptScore W2107029656C104317684 @default.
• W2107029656 hasConceptScore W2107029656C122172344 @default.
• W2107029656 hasConceptScore W2107029656C134651460 @default.
• W2107029656 hasConceptScore W2107029656C181199279 @default.
• W2107029656 hasConceptScore W2107029656C185592680 @default.
• W2107029656 hasConceptScore W2107029656C203014093 @default.
• W2107029656 hasConceptScore W2107029656C204241405 @default.
• W2107029656 hasConceptScore W2107029656C2776120307 @default.
• W2107029656 hasConceptScore W2107029656C2778048844 @default.
• W2107029656 hasConceptScore W2107029656C2778371730 @default.
• W2107029656 hasConceptScore W2107029656C2779691961 @default.
• W2107029656 hasConceptScore W2107029656C553450214 @default.
• W2107029656 hasConceptScore W2107029656C55493867 @default.
• W2107029656 hasConceptScore W2107029656C6350086 @default.
• W2107029656 hasConceptScore W2107029656C86803240 @default.

• next