Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107032007> ?p ?o ?g. }
- W2107032007 endingPage "1703" @default.
- W2107032007 startingPage "1698" @default.
- W2107032007 abstract "Adult rats chronically fed a high-fat (HF) diet maintain reduced sensitivity to cholecystokinin (CCK). We hypothesized that, similar to adult rats, pups fed a HF diet would also exhibit reduced sensitivity to CCK. To test this, male pups fed low-fat (LF) and HF isoenergetic (16.2 kJ/g) diets were administered CCK intraperitoneally (0.125-1 microg/kg) 1 wk following dietary adaptation. After receiving 0.5 microg/kg CCK, pups fed the HF diet suppressed food intake less (8.9 +/- 5.0%) than pups fed the LF diet (28.9 +/- 4.7%; P < 0.05) relative to intakes after saline administration. We then assessed the development and extinction of changes in CCK sensitivity by switching the diets between the groups. The HF-fed group, when switched to the LF diet, regained sensitivity by wk 4 and suppressed food intake following administration of 0.25 microg/kg CCK (33.1 +/- 5.7%; P < 0.05). The LF-fed group, when switched to the HF diet, lost sensitivity by wk 2 and did not suppress food intake after administrations of CCK compared with saline. Finally, we examined if HF-fed rats have an increased sensitivity to corn oil during brief access tests using a multibottle gustometer. At oil concentrations of 25, 75, and 100%, rats fed the HF diet sampled more oil than LF-fed rats (P < 0.05). These findings demonstrate that male rat pups fed a HF diet exhibit reduced sensitivity to CCK, the development of this reduced sensitivity is quicker than its extinction, and rats consuming a HF diet have increased oral sensitivity to oils." @default.
- W2107032007 created "2016-06-24" @default.
- W2107032007 creator A5047642898 @default.
- W2107032007 creator A5060613483 @default.
- W2107032007 creator A5090665283 @default.
- W2107032007 date "2010-09-01" @default.
- W2107032007 modified "2023-10-01" @default.
- W2107032007 title "Reduced Sensitivity to Cholecystokinin in Male Rats Fed a High-Fat Diet Is Reversible" @default.
- W2107032007 cites W1539768174 @default.
- W2107032007 cites W1777861434 @default.
- W2107032007 cites W1893825827 @default.
- W2107032007 cites W1950114297 @default.
- W2107032007 cites W1969776956 @default.
- W2107032007 cites W1970525327 @default.
- W2107032007 cites W1977860649 @default.
- W2107032007 cites W1978605242 @default.
- W2107032007 cites W1982336607 @default.
- W2107032007 cites W1985885724 @default.
- W2107032007 cites W1993548967 @default.
- W2107032007 cites W1994710817 @default.
- W2107032007 cites W1998429339 @default.
- W2107032007 cites W1999408156 @default.
- W2107032007 cites W2002512569 @default.
- W2107032007 cites W2011847859 @default.
- W2107032007 cites W2013537417 @default.
- W2107032007 cites W2016677234 @default.
- W2107032007 cites W2020661434 @default.
- W2107032007 cites W2022133939 @default.
- W2107032007 cites W2031178063 @default.
- W2107032007 cites W2032118416 @default.
- W2107032007 cites W2032500261 @default.
- W2107032007 cites W2037259478 @default.
- W2107032007 cites W2037566031 @default.
- W2107032007 cites W2040151175 @default.
- W2107032007 cites W2041614066 @default.
- W2107032007 cites W2044174926 @default.
- W2107032007 cites W2050387197 @default.
- W2107032007 cites W2050491079 @default.
- W2107032007 cites W2060798823 @default.
- W2107032007 cites W2062131758 @default.
- W2107032007 cites W2062636052 @default.
- W2107032007 cites W2066486037 @default.
- W2107032007 cites W2066770329 @default.
- W2107032007 cites W2069415022 @default.
- W2107032007 cites W2071614547 @default.
- W2107032007 cites W2072611005 @default.
- W2107032007 cites W2074267937 @default.
- W2107032007 cites W2089328602 @default.
- W2107032007 cites W2099277759 @default.
- W2107032007 cites W2124149838 @default.
- W2107032007 cites W2130507030 @default.
- W2107032007 cites W2158443718 @default.
- W2107032007 cites W2159074139 @default.
- W2107032007 cites W2181394749 @default.
- W2107032007 cites W2187535584 @default.
- W2107032007 cites W2418512602 @default.
- W2107032007 doi "https://doi.org/10.3945/jn.110.124149" @default.
- W2107032007 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20592106" @default.
- W2107032007 hasPublicationYear "2010" @default.
- W2107032007 type Work @default.
- W2107032007 sameAs 2107032007 @default.
- W2107032007 citedByCount "26" @default.
- W2107032007 countsByYear W21070320072012 @default.
- W2107032007 countsByYear W21070320072013 @default.
- W2107032007 countsByYear W21070320072014 @default.
- W2107032007 countsByYear W21070320072015 @default.
- W2107032007 countsByYear W21070320072016 @default.
- W2107032007 countsByYear W21070320072017 @default.
- W2107032007 countsByYear W21070320072019 @default.
- W2107032007 countsByYear W21070320072020 @default.
- W2107032007 countsByYear W21070320072021 @default.
- W2107032007 countsByYear W21070320072022 @default.
- W2107032007 countsByYear W21070320072023 @default.
- W2107032007 crossrefType "journal-article" @default.
- W2107032007 hasAuthorship W2107032007A5047642898 @default.
- W2107032007 hasAuthorship W2107032007A5060613483 @default.
- W2107032007 hasAuthorship W2107032007A5090665283 @default.
- W2107032007 hasBestOaLocation W21070320071 @default.
- W2107032007 hasConcept C126322002 @default.
- W2107032007 hasConcept C134018914 @default.
- W2107032007 hasConcept C170493617 @default.
- W2107032007 hasConcept C185592680 @default.
- W2107032007 hasConcept C2777397205 @default.
- W2107032007 hasConcept C2777593968 @default.
- W2107032007 hasConcept C2778206080 @default.
- W2107032007 hasConcept C3018685816 @default.
- W2107032007 hasConcept C71924100 @default.
- W2107032007 hasConcept C86803240 @default.
- W2107032007 hasConceptScore W2107032007C126322002 @default.
- W2107032007 hasConceptScore W2107032007C134018914 @default.
- W2107032007 hasConceptScore W2107032007C170493617 @default.
- W2107032007 hasConceptScore W2107032007C185592680 @default.
- W2107032007 hasConceptScore W2107032007C2777397205 @default.
- W2107032007 hasConceptScore W2107032007C2777593968 @default.
- W2107032007 hasConceptScore W2107032007C2778206080 @default.
- W2107032007 hasConceptScore W2107032007C3018685816 @default.
- W2107032007 hasConceptScore W2107032007C71924100 @default.
- W2107032007 hasConceptScore W2107032007C86803240 @default.