Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107081760> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2107081760 abstract "There is a lack of data on familial aggregation of colorectal cancer (CRC) in Iran. We aimed to determine the frequency of hereditary nonpolyposis colorectal cancer (HNPCC) and familial colorectal cancer (FCC) and to determine the frequency of extracolonic cancers in these families in Isfahan.We reviewed documents of all patients with a pathologically confirmed diagnosis of CRC admitted to Isfahan referral hospitals between 1995 and 2006. We also studied our CRC registry at Poursina Hakim Research Institute from 2003 to 2008. We found HNPCC and FCC families based on the Amsterdam II criteria and interviewed them for family history of CRC and extracolonic tumors. The family history was taken at least up to the second-degree relatives.During 1996 to 2008, a total of 2580 CRC cases have been diagnosed. We found 14 HNPCC and 53 FCC families. Mean age of CRC at diagnosis was 48.0 ± 14.6 and 49.0 ± 13.9 years in the HNPCC and FCC families, respectively (p > 0.05). The total numbers of observed extracolonic tumors were 70 (21.6%; mean age = 53.6 ± 11.0 years) and 157 (13.8%; mean age = 54.8 ± 18.0 years) in HNPCC and FCC families, respectively (p > 0.05). CRC was respectively found in 52 and 76 members of the HNPCC and FCC families, revealing the frequency of HNPCC and FCC as 2.0% (52/2580) and 2.9% (76/2580), respectively.We found a relative high frequency of HNPCC (2.0%) and FCC (2.9%) among CRC cases in our society and high incidence of extracolonic tumors in their families. Further studies focusing on molecular basis in this field and designing a specific screening and national cancer registry program for HNPCC and FCC families should be conducted." @default.
- W2107081760 created "2016-06-24" @default.
- W2107081760 creator A5024669670 @default.
- W2107081760 creator A5039907738 @default.
- W2107081760 creator A5046643448 @default.
- W2107081760 creator A5050562933 @default.
- W2107081760 date "2012-01-01" @default.
- W2107081760 modified "2023-09-23" @default.
- W2107081760 title "Hereditary nonpolyposis colorectal cancer and familial colorectal cancer in Central part of Iran, Isfahan." @default.
- W2107081760 cites W1483346992 @default.
- W2107081760 cites W1606901017 @default.
- W2107081760 cites W1934971502 @default.
- W2107081760 cites W1984128989 @default.
- W2107081760 cites W1998970984 @default.
- W2107081760 cites W2031898049 @default.
- W2107081760 cites W2031952060 @default.
- W2107081760 cites W2056450609 @default.
- W2107081760 cites W2069382191 @default.
- W2107081760 cites W2096371251 @default.
- W2107081760 cites W2099711395 @default.
- W2107081760 cites W2112677111 @default.
- W2107081760 cites W2114334874 @default.
- W2107081760 cites W2121016663 @default.
- W2107081760 cites W2124896165 @default.
- W2107081760 cites W2128793721 @default.
- W2107081760 cites W2136825333 @default.
- W2107081760 cites W2156299764 @default.
- W2107081760 cites W2167230176 @default.
- W2107081760 cites W2278456444 @default.
- W2107081760 cites W2418181926 @default.
- W2107081760 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3523440" @default.
- W2107081760 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23248659" @default.
- W2107081760 hasPublicationYear "2012" @default.
- W2107081760 type Work @default.
- W2107081760 sameAs 2107081760 @default.
- W2107081760 citedByCount "2" @default.
- W2107081760 countsByYear W21070817602016 @default.
- W2107081760 crossrefType "journal-article" @default.
- W2107081760 hasAuthorship W2107081760A5024669670 @default.
- W2107081760 hasAuthorship W2107081760A5039907738 @default.
- W2107081760 hasAuthorship W2107081760A5046643448 @default.
- W2107081760 hasAuthorship W2107081760A5050562933 @default.
- W2107081760 hasConcept C121608353 @default.
- W2107081760 hasConcept C126322002 @default.
- W2107081760 hasConcept C143998085 @default.
- W2107081760 hasConcept C2776135927 @default.
- W2107081760 hasConcept C2779862289 @default.
- W2107081760 hasConcept C2781179581 @default.
- W2107081760 hasConcept C512399662 @default.
- W2107081760 hasConcept C526805850 @default.
- W2107081760 hasConcept C71924100 @default.
- W2107081760 hasConcept C90924648 @default.
- W2107081760 hasConceptScore W2107081760C121608353 @default.
- W2107081760 hasConceptScore W2107081760C126322002 @default.
- W2107081760 hasConceptScore W2107081760C143998085 @default.
- W2107081760 hasConceptScore W2107081760C2776135927 @default.
- W2107081760 hasConceptScore W2107081760C2779862289 @default.
- W2107081760 hasConceptScore W2107081760C2781179581 @default.
- W2107081760 hasConceptScore W2107081760C512399662 @default.
- W2107081760 hasConceptScore W2107081760C526805850 @default.
- W2107081760 hasConceptScore W2107081760C71924100 @default.
- W2107081760 hasConceptScore W2107081760C90924648 @default.
- W2107081760 hasLocation W21070817601 @default.
- W2107081760 hasOpenAccess W2107081760 @default.
- W2107081760 hasPrimaryLocation W21070817601 @default.
- W2107081760 hasRelatedWork W1744426345 @default.
- W2107081760 hasRelatedWork W1964543140 @default.
- W2107081760 hasRelatedWork W1969349011 @default.
- W2107081760 hasRelatedWork W1981931230 @default.
- W2107081760 hasRelatedWork W2012548686 @default.
- W2107081760 hasRelatedWork W2019723965 @default.
- W2107081760 hasRelatedWork W2023536351 @default.
- W2107081760 hasRelatedWork W2025358062 @default.
- W2107081760 hasRelatedWork W2039070457 @default.
- W2107081760 hasRelatedWork W2055552754 @default.
- W2107081760 hasRelatedWork W2057946199 @default.
- W2107081760 hasRelatedWork W2085087786 @default.
- W2107081760 hasRelatedWork W2099711395 @default.
- W2107081760 hasRelatedWork W2111361757 @default.
- W2107081760 hasRelatedWork W2137488624 @default.
- W2107081760 hasRelatedWork W2146502841 @default.
- W2107081760 hasRelatedWork W2278456444 @default.
- W2107081760 hasRelatedWork W2376350388 @default.
- W2107081760 hasRelatedWork W2380453155 @default.
- W2107081760 hasRelatedWork W2897317105 @default.
- W2107081760 isParatext "false" @default.
- W2107081760 isRetracted "false" @default.
- W2107081760 magId "2107081760" @default.
- W2107081760 workType "article" @default.