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- W2107082879 abstract "ABSTRACT Synthesis of glutamate, the cell's major donor of nitrogen groups and principal anion, occupies a significant fraction of bacterial metabolism. In Bacillus subtilis , the gltAB operon, encoding glutamate synthase, requires a specific positive regulator, GltC, for its expression. In addition, the gltAB operon was shown to be repressed by TnrA, a regulator of several other genes of nitrogen metabolism and active under conditions of ammonium (nitrogen) limitation. TnrA was found to bind directly to a site immediately downstream of the gltAB promoter. As is true for other genes, the activity of TnrA at the gltAB promoter was antagonized by glutamine synthetase under certain growth conditions." @default.
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- W2107082879 date "2000-11-01" @default.
- W2107082879 modified "2023-10-12" @default.
- W2107082879 title "Role of TnrA in Nitrogen Source-Dependent Repression of <i>Bacillus subtilis</i> Glutamate Synthase Gene Expression" @default.
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- W2107082879 doi "https://doi.org/10.1128/jb.182.21.5939-5947.2000" @default.
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