Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107115979> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2107115979 endingPage "40" @default.
- W2107115979 startingPage "38" @default.
- W2107115979 abstract "The efficacy of flecainide acetate for conversion of atrial fibrillation into sinus rhythm was assessed in 69 patients (mean age of 63 ± 14 years). Mean duration of the arrhythmia was 49 ± 45 days. Mean cardiothoracic index was 0.49 ± 0.03. Flecainide treatment was started intravenously with a bolus of 2 mg/kg over 10 minutes, followed by oral treatment (200 to 300 mg/day) according to body weight. Conversion to sinus rhythm was obtained in 49 patients (71%). The mean delay between initiation of treatment and restoration of sinus rhythm was 301 minutes (range 5 to 1,600). The left atrial diameter was smaller (40 ± 1 mm) in patients who had successful cardioversion than in those who did not (46 ± 1 mm) (p < 0.05). Patients with atrial fibrillation lasting for less than 10 days had a higher conversion rate (79%) than patients with longstanding atrial fibrillation, in whom the conversion rate was only 38% (p < 0.05). Conversion to sinus rhythm occurred in 33 patients during the first 5 minutes after injection. Adverse effects necessitated discontinuation of treatment in 4 patients (5.8%). Gastrointestinal disorders and dizziness occurred in 5 other patients but did not necessitate discontinuing treatment. In conclusion, flecainide is an effective drug for converting atrial fibrillation into sinus rhythm. Unlike quinidine, flecainide can be administered intravenously. The conversion rate with flecainide is higher in patients with a shorter duration of atrial fibrillation and smaller atria." @default.
- W2107115979 created "2016-06-24" @default.
- W2107115979 creator A5005212352 @default.
- W2107115979 creator A5050577471 @default.
- W2107115979 creator A5057379626 @default.
- W2107115979 creator A5077578713 @default.
- W2107115979 date "1988-08-01" @default.
- W2107115979 modified "2023-10-06" @default.
- W2107115979 title "Restoration of sinus rhythm with flecainide in patients with atrial fibrillation" @default.
- W2107115979 cites W1893993450 @default.
- W2107115979 cites W1972129938 @default.
- W2107115979 cites W1979954581 @default.
- W2107115979 cites W1983235313 @default.
- W2107115979 cites W1986965840 @default.
- W2107115979 cites W1994244988 @default.
- W2107115979 cites W1995457670 @default.
- W2107115979 cites W1995742781 @default.
- W2107115979 cites W2013516943 @default.
- W2107115979 cites W2025618821 @default.
- W2107115979 cites W2026233332 @default.
- W2107115979 cites W2046369244 @default.
- W2107115979 cites W2049671328 @default.
- W2107115979 cites W2061927647 @default.
- W2107115979 cites W2089752666 @default.
- W2107115979 cites W2165015964 @default.
- W2107115979 cites W2249253713 @default.
- W2107115979 cites W2325395722 @default.
- W2107115979 cites W2471446929 @default.
- W2107115979 doi "https://doi.org/10.1016/0002-9149(88)90503-6" @default.
- W2107115979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3136634" @default.
- W2107115979 hasPublicationYear "1988" @default.
- W2107115979 type Work @default.
- W2107115979 sameAs 2107115979 @default.
- W2107115979 citedByCount "60" @default.
- W2107115979 countsByYear W21071159792014 @default.
- W2107115979 countsByYear W21071159792015 @default.
- W2107115979 countsByYear W21071159792018 @default.
- W2107115979 countsByYear W21071159792020 @default.
- W2107115979 countsByYear W21071159792022 @default.
- W2107115979 crossrefType "journal-article" @default.
- W2107115979 hasAuthorship W2107115979A5005212352 @default.
- W2107115979 hasAuthorship W2107115979A5050577471 @default.
- W2107115979 hasAuthorship W2107115979A5057379626 @default.
- W2107115979 hasAuthorship W2107115979A5077578713 @default.
- W2107115979 hasConcept C126322002 @default.
- W2107115979 hasConcept C164705383 @default.
- W2107115979 hasConcept C2775914520 @default.
- W2107115979 hasConcept C2777289489 @default.
- W2107115979 hasConcept C2778715236 @default.
- W2107115979 hasConcept C2779161974 @default.
- W2107115979 hasConcept C2779837460 @default.
- W2107115979 hasConcept C2780339425 @default.
- W2107115979 hasConcept C42219234 @default.
- W2107115979 hasConcept C43376680 @default.
- W2107115979 hasConcept C71924100 @default.
- W2107115979 hasConceptScore W2107115979C126322002 @default.
- W2107115979 hasConceptScore W2107115979C164705383 @default.
- W2107115979 hasConceptScore W2107115979C2775914520 @default.
- W2107115979 hasConceptScore W2107115979C2777289489 @default.
- W2107115979 hasConceptScore W2107115979C2778715236 @default.
- W2107115979 hasConceptScore W2107115979C2779161974 @default.
- W2107115979 hasConceptScore W2107115979C2779837460 @default.
- W2107115979 hasConceptScore W2107115979C2780339425 @default.
- W2107115979 hasConceptScore W2107115979C42219234 @default.
- W2107115979 hasConceptScore W2107115979C43376680 @default.
- W2107115979 hasConceptScore W2107115979C71924100 @default.
- W2107115979 hasIssue "6" @default.
- W2107115979 hasLocation W21071159791 @default.
- W2107115979 hasLocation W21071159792 @default.
- W2107115979 hasOpenAccess W2107115979 @default.
- W2107115979 hasPrimaryLocation W21071159791 @default.
- W2107115979 hasRelatedWork W1972651039 @default.
- W2107115979 hasRelatedWork W1974061424 @default.
- W2107115979 hasRelatedWork W2074475770 @default.
- W2107115979 hasRelatedWork W2141633106 @default.
- W2107115979 hasRelatedWork W2144417211 @default.
- W2107115979 hasRelatedWork W2317055961 @default.
- W2107115979 hasRelatedWork W2398363058 @default.
- W2107115979 hasRelatedWork W2403819404 @default.
- W2107115979 hasRelatedWork W2766800775 @default.
- W2107115979 hasRelatedWork W2919782842 @default.
- W2107115979 hasVolume "62" @default.
- W2107115979 isParatext "false" @default.
- W2107115979 isRetracted "false" @default.
- W2107115979 magId "2107115979" @default.
- W2107115979 workType "article" @default.