FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107130449> ?p ?o ?g. }

• W2107130449 endingPage "1543" @default.
• W2107130449 startingPage "1536" @default.
• W2107130449 abstract "Exponential growth in genomics has led to public and private initiatives worldwide that have dramatically increased the number of procreative couples who are aware of their ability to transmit genetic disorders to their future children. Understanding how couples process the meaning of being genetically at-risk for their procreative life lags far behind the advances in genomic and reproductive sciences. Moreover, society, policy makers, and clinicians are not aware of the experiences and nuances involved when modern couples are faced with using Preimplantation Genetic Diagnosis (PGD). The purpose of this study was to discover the decision-making process of genetically at-risk couples as they decide whether to use PGD to prevent the transmission of known single-gene or sex-linked genetic disorders to their children. A qualitative, grounded theory design guided the study in which 22 couples (44 individual partners) from the USA, who were actively considering PGD, participated. Couples were recruited from June 2009 to May 2010 from the Internet and from a large PGD center and a patient newsletter. In-depth semi-structured interviews were completed with each individual partner within the couple dyad, separate from their respective partner. We discovered that couples move through four phases (Identify, Contemplate, Resolve, Engage) of a complex, dynamic, and iterative decision-making process where multiple, sequential decisions are made. In the Identify phase, couples acknowledge the meaning of their at-risk status. Parenthood and reproductive options are explored in the Contemplate phase, where 41% of couples remained for up to 36 months before moving into the Resolve phase. In Resolve, one of three decisions about PGD use is reached, including: Accepting, Declining, or Oscillating. Actualizing decisions occur in the Engage phase. Awareness of the decision-making process among genetically at-risk couples provides foundational work for understanding critical processes and aids in identifying important gaps for intervention and future research." @default.
• W2107130449 created "2016-06-24" @default.
• W2107130449 creator A5008157250 @default.
• W2107130449 creator A5025323387 @default.
• W2107130449 creator A5055521522 @default.
• W2107130449 creator A5069909531 @default.
• W2107130449 creator A5069916710 @default.
• W2107130449 creator A5089297474 @default.
• W2107130449 date "2012-05-01" @default.
• W2107130449 modified "2023-09-30" @default.
• W2107130449 title "The decision-making process of genetically at-risk couples considering preimplantation genetic diagnosis: Initial findings from a grounded theory study" @default.
• W2107130449 cites W1480373472 @default.
• W2107130449 cites W1922738577 @default.
• W2107130449 cites W1970351466 @default.
• W2107130449 cites W1973098720 @default.
• W2107130449 cites W1974346013 @default.
• W2107130449 cites W1977302767 @default.
• W2107130449 cites W1981520497 @default.
• W2107130449 cites W1982048882 @default.
• W2107130449 cites W1982478788 @default.
• W2107130449 cites W2012254260 @default.
• W2107130449 cites W2016180071 @default.
• W2107130449 cites W2018816213 @default.
• W2107130449 cites W2020364975 @default.
• W2107130449 cites W2023798663 @default.
• W2107130449 cites W2032148036 @default.
• W2107130449 cites W2034198428 @default.
• W2107130449 cites W2036336974 @default.
• W2107130449 cites W2037045605 @default.
• W2107130449 cites W2038593932 @default.
• W2107130449 cites W2045492975 @default.
• W2107130449 cites W2050856265 @default.
• W2107130449 cites W2060578731 @default.
• W2107130449 cites W2062268192 @default.
• W2107130449 cites W2081456708 @default.
• W2107130449 cites W2081520406 @default.
• W2107130449 cites W2084085196 @default.
• W2107130449 cites W2086198096 @default.
• W2107130449 cites W2087398999 @default.
• W2107130449 cites W2092864046 @default.
• W2107130449 cites W2094916772 @default.
• W2107130449 cites W2106047276 @default.
• W2107130449 cites W2107309186 @default.
• W2107130449 cites W2109833490 @default.
• W2107130449 cites W2130616852 @default.
• W2107130449 cites W2133103930 @default.
• W2107130449 cites W2141192564 @default.
• W2107130449 cites W2147226578 @default.
• W2107130449 cites W2151368285 @default.
• W2107130449 cites W2155608046 @default.
• W2107130449 cites W2157350681 @default.
• W2107130449 cites W2158452114 @default.
• W2107130449 cites W2160493645 @default.
• W2107130449 cites W2163137418 @default.
• W2107130449 cites W2167218074 @default.
• W2107130449 cites W2168926796 @default.
• W2107130449 cites W2170286226 @default.
• W2107130449 cites W4234708366 @default.
• W2107130449 doi "https://doi.org/10.1016/j.socscimed.2012.02.003" @default.
• W2107130449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3328546" @default.
• W2107130449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22445765" @default.
• W2107130449 hasPublicationYear "2012" @default.
• W2107130449 type Work @default.
• W2107130449 sameAs 2107130449 @default.
• W2107130449 citedByCount "50" @default.
• W2107130449 countsByYear W21071304492013 @default.
• W2107130449 countsByYear W21071304492014 @default.
• W2107130449 countsByYear W21071304492015 @default.
• W2107130449 countsByYear W21071304492016 @default.
• W2107130449 countsByYear W21071304492017 @default.
• W2107130449 countsByYear W21071304492018 @default.
• W2107130449 countsByYear W21071304492019 @default.
• W2107130449 countsByYear W21071304492020 @default.
• W2107130449 countsByYear W21071304492021 @default.
• W2107130449 countsByYear W21071304492022 @default.
• W2107130449 countsByYear W21071304492023 @default.
• W2107130449 crossrefType "journal-article" @default.
• W2107130449 hasAuthorship W2107130449A5008157250 @default.
• W2107130449 hasAuthorship W2107130449A5025323387 @default.
• W2107130449 hasAuthorship W2107130449A5055521522 @default.
• W2107130449 hasAuthorship W2107130449A5069909531 @default.
• W2107130449 hasAuthorship W2107130449A5069916710 @default.
• W2107130449 hasAuthorship W2107130449A5089297474 @default.
• W2107130449 hasBestOaLocation W21071304492 @default.
• W2107130449 hasConcept C138496976 @default.
• W2107130449 hasConcept C144024400 @default.
• W2107130449 hasConcept C156325361 @default.
• W2107130449 hasConcept C15744967 @default.
• W2107130449 hasConcept C190248442 @default.
• W2107130449 hasConcept C2777716012 @default.
• W2107130449 hasConcept C2778805741 @default.
• W2107130449 hasConcept C2779234561 @default.
• W2107130449 hasConcept C2780876879 @default.
• W2107130449 hasConcept C36289849 @default.
• W2107130449 hasConcept C542102704 @default.
• W2107130449 hasConcept C54355233 @default.
• W2107130449 hasConcept C77805123 @default.
• W2107130449 hasConcept C86803240 @default.

• next