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- W2107162637 abstract "Potential toxicity of radioactive albumin and relatively high radiation dose of chelated 169Yb, particularly under certain pathological conditions, could be overcome by 111In chelated with diethylenetriaminepentaacetic acid. To approximately 10 mCi of cyclotron produced 111In in weak HC1 0·5 mg of DTPA was added, and the pH was adjusted to seven and made isotonic. Sterilized and pyrogen tested 111 In-DTPA in doses of about 500 μCi in 0·5–2 ml volume were injected intrathecally to obtain cisternograms at 2, 6, 24 and 48 hours. Results were highly satisfactory. The 2·81 day half-life of 111In permits adequate quality control and allows studies for desired length of time. 111In-DTPA having minimal foreign chemicals and desirable photon characteristics could be regarded as an ideal radiopharmaceutical for cerebrospinal fluid imaging." @default.
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- W2107162637 date "1972-09-01" @default.
- W2107162637 modified "2023-10-18" @default.
- W2107162637 title "Chelated<sup>111</sup>In: an ideal radiopharmaceutical for cisternography" @default.
- W2107162637 cites W2054778572 @default.
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- W2107162637 doi "https://doi.org/10.1259/0007-1285-45-537-677" @default.
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