FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107165228> ?p ?o ?g. }

• W2107165228 endingPage "38" @default.
• W2107165228 startingPage "38" @default.
• W2107165228 abstract "The Damaraland mole-rat (Fukomys damarensis) is a eusocial, subterranean mammal, which exhibits an extreme reproductive skew with a single female (queen) monopolizing reproduction in each colony. Non-reproductive females in the presence of the queen are physiologically suppressed to the extent that they are anovulatory. This blockade is thought to be caused by a disruption in the normal gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus. In order to understand the underlying physiological mechanisms of reproductive suppression in subordinate females we studied the expression of steroid hormone receptors and the androgen-converting enzyme aromatase in forebrain regions involved in the control of reproductive behaviour in female breeders and non-breeders from intact colonies. Additionally, we included in our analysis females that experienced the release from social suppression by being removed from the presence of the queen. We found expression of androgen receptor, estrogen receptor α and aromatase in several forebrain regions of female Damaraland mole-rats. Their distribution matches previous findings in other mammals. Quantification of the hybridisation signal revealed that queens had increased expression of androgen receptors compared to non-breeders and removed non-breeders in most brain regions examined, which include the medial preoptic area (MPOA), the principal nucleus of the bed nucleus of the stria terminalis (BSTp), the ventromedial nucleus of the hypothalamus (VMH), the arcuate nucleus (ARC) and the medial amygdala (MeA). Furthermore, breeders had increased estrogen receptor α expression in the anteroventral periventricular nucleus (AVPV) and in the MeA, while aromatase expression in the AVPV was significantly reduced compared to non-breeders. Absence of social suppression was associated with increased androgen receptor expression in the ARC, increased estrogen receptor α expression in the MeA and BSTp and reduced aromatase expression in the AVPV. This study shows that social suppression and breeding differentially affect the neuroendocrine phenotype of female Damaraland mole-rats. The differential expression pattern of estrogen receptor α and aromatase in the AVPV between breeders and non-breeders supports the view that this region plays an important role in mediating the physiological suppression in subordinate females." @default.
• W2107165228 created "2016-06-24" @default.
• W2107165228 creator A5002212307 @default.
• W2107165228 creator A5021331666 @default.
• W2107165228 creator A5042841583 @default.
• W2107165228 creator A5045390769 @default.
• W2107165228 creator A5048401390 @default.
• W2107165228 date "2014-01-01" @default.
• W2107165228 modified "2023-09-24" @default.
• W2107165228 title "Breeding status and social environment differentially affect the expression of sex steroid receptor and aromatase mRNA in the brain of female Damaraland mole-rats" @default.
• W2107165228 cites W1963435647 @default.
• W2107165228 cites W1964557619 @default.
• W2107165228 cites W1975890243 @default.
• W2107165228 cites W1979535003 @default.
• W2107165228 cites W1984902037 @default.
• W2107165228 cites W1990342353 @default.
• W2107165228 cites W1998286971 @default.
• W2107165228 cites W1998407591 @default.
• W2107165228 cites W2006727096 @default.
• W2107165228 cites W2008563038 @default.
• W2107165228 cites W2012743701 @default.
• W2107165228 cites W2016704563 @default.
• W2107165228 cites W2018762303 @default.
• W2107165228 cites W2020929618 @default.
• W2107165228 cites W2037878404 @default.
• W2107165228 cites W2042282297 @default.
• W2107165228 cites W2043625248 @default.
• W2107165228 cites W2050581082 @default.
• W2107165228 cites W2054011129 @default.
• W2107165228 cites W2062207814 @default.
• W2107165228 cites W2063500033 @default.
• W2107165228 cites W2067130406 @default.
• W2107165228 cites W2073292236 @default.
• W2107165228 cites W2074879886 @default.
• W2107165228 cites W2076082057 @default.
• W2107165228 cites W2078288264 @default.
• W2107165228 cites W2081650344 @default.
• W2107165228 cites W2083501722 @default.
• W2107165228 cites W2085638249 @default.
• W2107165228 cites W2092146757 @default.
• W2107165228 cites W2111516838 @default.
• W2107165228 cites W2111824942 @default.
• W2107165228 cites W2129003675 @default.
• W2107165228 cites W2131622329 @default.
• W2107165228 cites W2141607896 @default.
• W2107165228 cites W2145865543 @default.
• W2107165228 cites W2155616494 @default.
• W2107165228 cites W2158893781 @default.
• W2107165228 doi "https://doi.org/10.1186/1742-9994-11-38" @default.
• W2107165228 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4024188" @default.
• W2107165228 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24839456" @default.
• W2107165228 hasPublicationYear "2014" @default.
• W2107165228 type Work @default.
• W2107165228 sameAs 2107165228 @default.
• W2107165228 citedByCount "19" @default.
• W2107165228 countsByYear W21071652282015 @default.
• W2107165228 countsByYear W21071652282016 @default.
• W2107165228 countsByYear W21071652282017 @default.
• W2107165228 countsByYear W21071652282018 @default.
• W2107165228 countsByYear W21071652282019 @default.
• W2107165228 countsByYear W21071652282022 @default.
• W2107165228 countsByYear W21071652282023 @default.
• W2107165228 crossrefType "journal-article" @default.
• W2107165228 hasAuthorship W2107165228A5002212307 @default.
• W2107165228 hasAuthorship W2107165228A5021331666 @default.
• W2107165228 hasAuthorship W2107165228A5042841583 @default.
• W2107165228 hasAuthorship W2107165228A5045390769 @default.
• W2107165228 hasAuthorship W2107165228A5048401390 @default.
• W2107165228 hasBestOaLocation W21071652281 @default.
• W2107165228 hasConcept C121608353 @default.
• W2107165228 hasConcept C126322002 @default.
• W2107165228 hasConcept C134018914 @default.
• W2107165228 hasConcept C2776166826 @default.
• W2107165228 hasConcept C2777003273 @default.
• W2107165228 hasConcept C2777911890 @default.
• W2107165228 hasConcept C2778652331 @default.
• W2107165228 hasConcept C2779715522 @default.
• W2107165228 hasConcept C2779938979 @default.
• W2107165228 hasConcept C2780902042 @default.
• W2107165228 hasConcept C2781115071 @default.
• W2107165228 hasConcept C529278444 @default.
• W2107165228 hasConcept C530470458 @default.
• W2107165228 hasConcept C54355233 @default.
• W2107165228 hasConcept C71315377 @default.
• W2107165228 hasConcept C71924100 @default.
• W2107165228 hasConcept C84606932 @default.
• W2107165228 hasConcept C86803240 @default.
• W2107165228 hasConceptScore W2107165228C121608353 @default.
• W2107165228 hasConceptScore W2107165228C126322002 @default.
• W2107165228 hasConceptScore W2107165228C134018914 @default.
• W2107165228 hasConceptScore W2107165228C2776166826 @default.
• W2107165228 hasConceptScore W2107165228C2777003273 @default.
• W2107165228 hasConceptScore W2107165228C2777911890 @default.
• W2107165228 hasConceptScore W2107165228C2778652331 @default.
• W2107165228 hasConceptScore W2107165228C2779715522 @default.
• W2107165228 hasConceptScore W2107165228C2779938979 @default.
• W2107165228 hasConceptScore W2107165228C2780902042 @default.
• W2107165228 hasConceptScore W2107165228C2781115071 @default.

• next