Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107168983> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2107168983 endingPage "2745" @default.
- W2107168983 startingPage "2739" @default.
- W2107168983 abstract "Of the known risk factors for chronic kidney disease (CKD), race represents one that is non-modifiable, while smoking is another that is modifiable. Moreover, smoking tends to increase red blood cell mass, which is frequently diminished in CKD. No studies have examined the interplay of race with smoking on anaemia management in patients with CKD.We examined the effects of smoking on anaemia management in CKD and its variation across race in a previously conducted study of CKD patients (n = 1312) initiated on weekly epoetin alfa and followed for 16 weeks. Smoking status was classified as current vs non-smoker. Race was classified as African-American vs non-African-American. Changes in estimated glomerular filtration rate, urinary albumin excretion, and erythropoietic response to weekly epoetin alfa were examined.Overall, African-Americans had lower baseline Hb than non-African-Americans. African-American non-smokers did not mount an erythropoetic response comparable to other non-smokers by final Hb (mean 11.29 g/dl vs 11.64 g/dl, P<0.001) or week 16 Hb (mean 11.61 g/dl vs 11.86 g/dl, P = 0.02). However, African-American smokers had a more significant erythropoietic response than their non-smoking counterparts and were comparable to their smoking non-African-American counterparts. There was no effect of smoking on renal function or urinary protein excretion over the course of the study.African-American non-smokers exhibit a diminished response to standard epoetin alfa dosing than non-smokers in other races. However, African-American smokers with CKD exhibit a response to epoetin alfa comparable to patients of other races. These findings may have implications for African-Americans who have CKD-related anaemia." @default.
- W2107168983 created "2016-06-24" @default.
- W2107168983 creator A5019406645 @default.
- W2107168983 creator A5020433696 @default.
- W2107168983 creator A5028635098 @default.
- W2107168983 creator A5082369645 @default.
- W2107168983 creator A5086744652 @default.
- W2107168983 creator A5089603612 @default.
- W2107168983 date "2005-10-04" @default.
- W2107168983 modified "2023-09-24" @default.
- W2107168983 title "Racial variations in erythropoietic response to epoetin alfa in chronic kidney disease and the impact of smoking" @default.
- W2107168983 cites W1572874245 @default.
- W2107168983 cites W1974218285 @default.
- W2107168983 cites W1978192411 @default.
- W2107168983 cites W1988296336 @default.
- W2107168983 cites W2023113567 @default.
- W2107168983 cites W2041030953 @default.
- W2107168983 cites W2085191348 @default.
- W2107168983 cites W2099422638 @default.
- W2107168983 cites W2101619401 @default.
- W2107168983 cites W2120235169 @default.
- W2107168983 cites W2123865460 @default.
- W2107168983 cites W2163873216 @default.
- W2107168983 cites W2170414722 @default.
- W2107168983 cites W2333113037 @default.
- W2107168983 cites W4232139259 @default.
- W2107168983 doi "https://doi.org/10.1093/ndt/gfi128" @default.
- W2107168983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16188897" @default.
- W2107168983 hasPublicationYear "2005" @default.
- W2107168983 type Work @default.
- W2107168983 sameAs 2107168983 @default.
- W2107168983 citedByCount "8" @default.
- W2107168983 countsByYear W21071689832012 @default.
- W2107168983 countsByYear W21071689832020 @default.
- W2107168983 crossrefType "journal-article" @default.
- W2107168983 hasAuthorship W2107168983A5019406645 @default.
- W2107168983 hasAuthorship W2107168983A5020433696 @default.
- W2107168983 hasAuthorship W2107168983A5028635098 @default.
- W2107168983 hasAuthorship W2107168983A5082369645 @default.
- W2107168983 hasAuthorship W2107168983A5086744652 @default.
- W2107168983 hasAuthorship W2107168983A5089603612 @default.
- W2107168983 hasBestOaLocation W21071689831 @default.
- W2107168983 hasConcept C126322002 @default.
- W2107168983 hasConcept C159641895 @default.
- W2107168983 hasConcept C2549261 @default.
- W2107168983 hasConcept C2776164570 @default.
- W2107168983 hasConcept C2778534260 @default.
- W2107168983 hasConcept C2778653478 @default.
- W2107168983 hasConcept C2987028688 @default.
- W2107168983 hasConcept C71924100 @default.
- W2107168983 hasConcept C77411442 @default.
- W2107168983 hasConcept C90924648 @default.
- W2107168983 hasConcept C95457728 @default.
- W2107168983 hasConceptScore W2107168983C126322002 @default.
- W2107168983 hasConceptScore W2107168983C159641895 @default.
- W2107168983 hasConceptScore W2107168983C2549261 @default.
- W2107168983 hasConceptScore W2107168983C2776164570 @default.
- W2107168983 hasConceptScore W2107168983C2778534260 @default.
- W2107168983 hasConceptScore W2107168983C2778653478 @default.
- W2107168983 hasConceptScore W2107168983C2987028688 @default.
- W2107168983 hasConceptScore W2107168983C71924100 @default.
- W2107168983 hasConceptScore W2107168983C77411442 @default.
- W2107168983 hasConceptScore W2107168983C90924648 @default.
- W2107168983 hasConceptScore W2107168983C95457728 @default.
- W2107168983 hasIssue "12" @default.
- W2107168983 hasLocation W21071689831 @default.
- W2107168983 hasLocation W21071689832 @default.
- W2107168983 hasOpenAccess W2107168983 @default.
- W2107168983 hasPrimaryLocation W21071689831 @default.
- W2107168983 hasRelatedWork W1964706798 @default.
- W2107168983 hasRelatedWork W2014074349 @default.
- W2107168983 hasRelatedWork W2040029744 @default.
- W2107168983 hasRelatedWork W2100854655 @default.
- W2107168983 hasRelatedWork W2130171323 @default.
- W2107168983 hasRelatedWork W2320002543 @default.
- W2107168983 hasRelatedWork W2414110362 @default.
- W2107168983 hasRelatedWork W2588445257 @default.
- W2107168983 hasRelatedWork W4206651050 @default.
- W2107168983 hasRelatedWork W4318274818 @default.
- W2107168983 hasVolume "20" @default.
- W2107168983 isParatext "false" @default.
- W2107168983 isRetracted "false" @default.
- W2107168983 magId "2107168983" @default.
- W2107168983 workType "article" @default.