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- W2107192347 abstract "In this paper we describe a microcomputer program (HTP) for predicting the location and orientation of α-helical transmemhrane segments in integral membrane proteins. HTP is a neural network-based tool which gives as output the protein membrane topology based on the statistical propensity of residues to be located in external and internal loops. This method, which uses single protein sequences as input to the network system, correctly predicts the topology of 71 out of 92 membrane proteins of putative membrane orientation, independently of the protein source." @default.
- W2107192347 created "2016-06-24" @default.
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- W2107192347 creator A5060232841 @default.
- W2107192347 date "1996-01-01" @default.
- W2107192347 modified "2023-10-16" @default.
- W2107192347 title "HTP: a neural network-based method for predicting the topology of helical transmembrane domains in proteins" @default.
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- W2107192347 doi "https://doi.org/10.1093/bioinformatics/12.1.41" @default.
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