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- W2107384925 abstract "BackgroundPortal vein embolization (PVE) is used before extensive hepatic resections to increase the volume of the future remnant liver within acceptable safety margins (conventionally >0.6% of the patient's weight). The objective was to determine whether pre‐operative PVE impacts on post‐operative liver function independently from the increase in liver volume.MethodsThe post‐operative liver function of patients who underwent an anatomical right liver resection with (n = 28) and without (n = 53) PVE were retrospectively analysed. Donors of the right liver were also analysed (LD) (n = 17).ResultsPatient characteristics were similar, except for age, weight and American Society of Anesthesiologists (ASA) score that were lower in LD. Post‐operative factor V and bilirubin levels were, respectively, higher and lower in patients with PVE compared with patients without PVE or LD (P < 0.05). Patients with PVE had an increased blood loss, blood transfusions and sinusoidal obstruction syndrome. The day‐3 bilirubin level was 40% lower in the PVE group compared with the no‐PVE group after adjustment for body weight, chemotherapy, operating time, Pringle time, blood transfusions, remnant liver volume, pre‐operative bilirubin level and pre‐operative prothrombin ratio (P = 0.001).ConclusionsFor equivalent volumes, the immediate post‐operative hepatic function appears to be better in livers prepared with PVE than in unprepared livers. Future studies should analyse whether the conventional inferior volume limit that allows a safe liver resection may be lowered when a PVE is performed." @default.
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- W2107384925 date "2015-11-01" @default.
- W2107384925 modified "2023-10-18" @default.
- W2107384925 title "Improved liver function after portal vein embolization and an elective right hepatectomy" @default.
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- W2107384925 doi "https://doi.org/10.1111/hpb.12501" @default.
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