FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107445130> ?p ?o ?g. }

• W2107445130 endingPage "NMI.S5862" @default.
• W2107445130 startingPage "NMI.S5862" @default.
• W2107445130 abstract "Background Malnutrition is a major global public health issue and its impact on communities and individuals is more dramatic in Sub-Saharan Africa, where it is compounded by widespread poverty and generalized high prevalence of human immunodeficiency virus (HIV). Therefore, malnutrition should be addressed through a multisectorial approach, and malnourished individuals should have access to nutritional rehabilitation molecules that are affordable, accessible, rich in nutrient and efficient. We thus assessed the efficacy of two affordable and accessible nutritional supplements, spirulina platensis versus soya beans among malnourished HIV-infected adults. Methods Undernourished patients, naïve of, but eligible to antiretroviral treatment (ART), aged 18 to 35 years were enrolled and randomly assigned to two groups. The first group received spirulina (Group A) as food supplement and the second received soya beans (Group B). Patients were initiated ART simultaneously with supplements. Food supplements were auto-administered daily, the quantity being calculated according to weight to provide 1.5 g/kg body weight of proteins with 25% from supplements (spirulina and soya beans). Patients were monitored at baseline and followed-up during twelve weeks for anthropometric parameters, body composition, haemoglobin and serum albumin, CD4 count and viral load. Results Fifty-two patients were enrolled (Group A: 26 and Group B: 26). The mean age was 26.4 ± 4.9 years (Group A) and 28.7 ± 4.8 (Group B) with no significant difference between groups ( P = 0.10). After 12 weeks, weight and BMI significantly improved in both groups ( P < 0.001 within each group). The mean gain in weight and BMI in Group A and B were 4.8 vs. 6.5 kg, ( P = 0.68) and 1.3 vs. 1.90 Kg/m 2 , ( P = 0.82) respectively. In terms of body composition, fat free mass (FFM) did not significantly increase within each group (40.5 vs. 42.2 Kg, P = 0.56 for Group A; 39.2 vs. 39.0 Kg, P = 0.22 for Group B). But when compared between the two groups at the end of the trial, FFM was significantly higher in the spirulina group (42.2 vs. 39.0 Kg, P = 0.01). The haemoglobin level rose significantly within groups ( P < 0.001 for each group) with no difference between groups ( P = 0.77). Serum albumin level did not increase significantly within groups ( P < 0.90 vs. P < 0.82) with no difference between groups ( P = 0.39). The increase in CD4 cell count within groups was significant ( P < 0.01 in both groups), with a significantly higher CD4 count in the spirulina group compared to subjects on soya beans at the end of the study ( P = 0.02). Within each group, HIV viral load significantly reduced at the end of the study ( P < 0.001 and P = 0.04 for spirulina and soya beans groups respectively). Between the groups, the viral load was similar at baseline but significantly reduced in the spirulina group at the end of the study ( P = 0.02). Conclusion We therefore conclude in this preliminary study, firstly, that both spirulina and soja improve on nutritional status of malnourished HIV-infected patients but in terms of quality of nutritional improvement, subjects on spirulina were better off than subjects on soya beans. Secondly, nutritional rehabilitation improves on immune status with a consequent drop in viral load but further investigations on the antiviral effects of this alga and its clinical implications are strongly needed." @default.
• W2107445130 created "2016-06-24" @default.
• W2107445130 creator A5000185410 @default.
• W2107445130 creator A5005706371 @default.
• W2107445130 creator A5012680119 @default.
• W2107445130 creator A5023103983 @default.
• W2107445130 creator A5027840918 @default.
• W2107445130 creator A5058575023 @default.
• W2107445130 creator A5061063097 @default.
• W2107445130 creator A5071591370 @default.
• W2107445130 creator A5079891785 @default.
• W2107445130 creator A5081890342 @default.
• W2107445130 creator A5088641953 @default.
• W2107445130 date "2011-01-01" @default.
• W2107445130 modified "2023-10-16" @default.
• W2107445130 title "Potential of<i>Spirulina Platensis</i>as a Nutritional Supplement in Malnourished HIV-Infected Adults in Sub-Saharan Africa: A Randomised, Single-Blind Study" @default.
• W2107445130 cites W1846408420 @default.
• W2107445130 cites W1966391174 @default.
• W2107445130 cites W1987804135 @default.
• W2107445130 cites W1995255465 @default.
• W2107445130 cites W2003358339 @default.
• W2107445130 cites W2005150070 @default.
• W2107445130 cites W2011233600 @default.
• W2107445130 cites W2017434644 @default.
• W2107445130 cites W2033756224 @default.
• W2107445130 cites W2033935843 @default.
• W2107445130 cites W2038253321 @default.
• W2107445130 cites W2042733040 @default.
• W2107445130 cites W2058217770 @default.
• W2107445130 cites W2060919596 @default.
• W2107445130 cites W2070558085 @default.
• W2107445130 cites W2077878295 @default.
• W2107445130 cites W2096099449 @default.
• W2107445130 cites W2097770102 @default.
• W2107445130 cites W2107656039 @default.
• W2107445130 cites W2137820243 @default.
• W2107445130 cites W2142702699 @default.
• W2107445130 cites W2143494023 @default.
• W2107445130 cites W2146655659 @default.
• W2107445130 cites W2147535816 @default.
• W2107445130 cites W2148464428 @default.
• W2107445130 cites W2165770342 @default.
• W2107445130 cites W2255816830 @default.
• W2107445130 cites W2308488797 @default.
• W2107445130 cites W2328773688 @default.
• W2107445130 cites W2331078321 @default.
• W2107445130 cites W2515171174 @default.
• W2107445130 cites W4239888395 @default.
• W2107445130 doi "https://doi.org/10.4137/nmi.s5862" @default.
• W2107445130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3738485" @default.
• W2107445130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23946659" @default.
• W2107445130 hasPublicationYear "2011" @default.
• W2107445130 type Work @default.
• W2107445130 sameAs 2107445130 @default.
• W2107445130 citedByCount "35" @default.
• W2107445130 countsByYear W21074451302014 @default.
• W2107445130 countsByYear W21074451302015 @default.
• W2107445130 countsByYear W21074451302016 @default.
• W2107445130 countsByYear W21074451302017 @default.
• W2107445130 countsByYear W21074451302018 @default.
• W2107445130 countsByYear W21074451302019 @default.
• W2107445130 countsByYear W21074451302020 @default.
• W2107445130 countsByYear W21074451302021 @default.
• W2107445130 countsByYear W21074451302022 @default.
• W2107445130 countsByYear W21074451302023 @default.
• W2107445130 crossrefType "journal-article" @default.
• W2107445130 hasAuthorship W2107445130A5000185410 @default.
• W2107445130 hasAuthorship W2107445130A5005706371 @default.
• W2107445130 hasAuthorship W2107445130A5012680119 @default.
• W2107445130 hasAuthorship W2107445130A5023103983 @default.
• W2107445130 hasAuthorship W2107445130A5027840918 @default.
• W2107445130 hasAuthorship W2107445130A5058575023 @default.
• W2107445130 hasAuthorship W2107445130A5061063097 @default.
• W2107445130 hasAuthorship W2107445130A5071591370 @default.
• W2107445130 hasAuthorship W2107445130A5079891785 @default.
• W2107445130 hasAuthorship W2107445130A5081890342 @default.
• W2107445130 hasAuthorship W2107445130A5088641953 @default.
• W2107445130 hasBestOaLocation W21074451301 @default.
• W2107445130 hasConcept C126322002 @default.
• W2107445130 hasConcept C168563851 @default.
• W2107445130 hasConcept C18903297 @default.
• W2107445130 hasConcept C203014093 @default.
• W2107445130 hasConcept C206139338 @default.
• W2107445130 hasConcept C2779784034 @default.
• W2107445130 hasConcept C2908924572 @default.
• W2107445130 hasConcept C3013748606 @default.
• W2107445130 hasConcept C551997983 @default.
• W2107445130 hasConcept C61427482 @default.
• W2107445130 hasConcept C71924100 @default.
• W2107445130 hasConcept C86803240 @default.
• W2107445130 hasConceptScore W2107445130C126322002 @default.
• W2107445130 hasConceptScore W2107445130C168563851 @default.
• W2107445130 hasConceptScore W2107445130C18903297 @default.
• W2107445130 hasConceptScore W2107445130C203014093 @default.
• W2107445130 hasConceptScore W2107445130C206139338 @default.
• W2107445130 hasConceptScore W2107445130C2779784034 @default.
• W2107445130 hasConceptScore W2107445130C2908924572 @default.
• W2107445130 hasConceptScore W2107445130C3013748606 @default.

• next