Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107577401> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2107577401 endingPage "89" @default.
- W2107577401 startingPage "82" @default.
- W2107577401 abstract "To date there is no generally accepted method to test the validity of algorithms used to compute likelihood ratios (LR) evaluating forensic DNA profiles from low-template and/or degraded samples. An upper bound on the LR is provided by the inverse of the match probability, which is the usual measure of weight of evidence for standard DNA profiles not subject to the stochastic effects that are the hallmark of low-template profiles. However, even for low-template profiles the LR in favour of a true prosecution hypothesis should approach this bound as the number of profiling replicates increases, provided that the queried contributor is the major contributor. Moreover, for sufficiently many replicates the standard LR for mixtures is often surpassed by the low-template LR. It follows that multiple LTDNA replicates can provide stronger evidence for a contributor to a mixture than a standard analysis of a good-quality profile. Here, we examine the performance of the likeLTD software for up to eight replicate profiling runs. We consider simulated and laboratory-generated replicates as well as resampling replicates from a real crime case. We show that LRs generated by likeLTD usually do exceed the mixture LR given sufficient replicates, are bounded above by the inverse match probability and do approach this bound closely when this is expected. We also show good performance of likeLTD even when a large majority of alleles are designated as uncertain, and suggest that there can be advantages to using different profiling sensitivities for different replicates. Overall, our results support both the validity of the underlying mathematical model and its correct implementation in the likeLTD software." @default.
- W2107577401 created "2016-06-24" @default.
- W2107577401 creator A5057999818 @default.
- W2107577401 creator A5077954390 @default.
- W2107577401 creator A5090210099 @default.
- W2107577401 date "2014-11-01" @default.
- W2107577401 modified "2023-10-03" @default.
- W2107577401 title "Verifying likelihoods for low template DNA profiles using multiple replicates" @default.
- W2107577401 cites W1972906909 @default.
- W2107577401 cites W2017753330 @default.
- W2107577401 cites W2064043771 @default.
- W2107577401 cites W2068764850 @default.
- W2107577401 cites W2111640582 @default.
- W2107577401 cites W2114431119 @default.
- W2107577401 cites W2118103837 @default.
- W2107577401 cites W2120523528 @default.
- W2107577401 cites W2128911215 @default.
- W2107577401 cites W2150098756 @default.
- W2107577401 cites W2151343700 @default.
- W2107577401 cites W2159429676 @default.
- W2107577401 cites W2161000848 @default.
- W2107577401 cites W2171014865 @default.
- W2107577401 doi "https://doi.org/10.1016/j.fsigen.2014.06.018" @default.
- W2107577401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4234080" @default.
- W2107577401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25082140" @default.
- W2107577401 hasPublicationYear "2014" @default.
- W2107577401 type Work @default.
- W2107577401 sameAs 2107577401 @default.
- W2107577401 citedByCount "21" @default.
- W2107577401 countsByYear W21075774012015 @default.
- W2107577401 countsByYear W21075774012016 @default.
- W2107577401 countsByYear W21075774012017 @default.
- W2107577401 countsByYear W21075774012018 @default.
- W2107577401 countsByYear W21075774012019 @default.
- W2107577401 countsByYear W21075774012020 @default.
- W2107577401 countsByYear W21075774012021 @default.
- W2107577401 countsByYear W21075774012022 @default.
- W2107577401 crossrefType "journal-article" @default.
- W2107577401 hasAuthorship W2107577401A5057999818 @default.
- W2107577401 hasAuthorship W2107577401A5077954390 @default.
- W2107577401 hasAuthorship W2107577401A5090210099 @default.
- W2107577401 hasBestOaLocation W21075774011 @default.
- W2107577401 hasConcept C105795698 @default.
- W2107577401 hasConcept C111919701 @default.
- W2107577401 hasConcept C11413529 @default.
- W2107577401 hasConcept C134306372 @default.
- W2107577401 hasConcept C150921843 @default.
- W2107577401 hasConcept C187191949 @default.
- W2107577401 hasConcept C2781162219 @default.
- W2107577401 hasConcept C33923547 @default.
- W2107577401 hasConcept C41008148 @default.
- W2107577401 hasConcept C77553402 @default.
- W2107577401 hasConceptScore W2107577401C105795698 @default.
- W2107577401 hasConceptScore W2107577401C111919701 @default.
- W2107577401 hasConceptScore W2107577401C11413529 @default.
- W2107577401 hasConceptScore W2107577401C134306372 @default.
- W2107577401 hasConceptScore W2107577401C150921843 @default.
- W2107577401 hasConceptScore W2107577401C187191949 @default.
- W2107577401 hasConceptScore W2107577401C2781162219 @default.
- W2107577401 hasConceptScore W2107577401C33923547 @default.
- W2107577401 hasConceptScore W2107577401C41008148 @default.
- W2107577401 hasConceptScore W2107577401C77553402 @default.
- W2107577401 hasLocation W21075774011 @default.
- W2107577401 hasLocation W21075774012 @default.
- W2107577401 hasLocation W21075774013 @default.
- W2107577401 hasLocation W21075774014 @default.
- W2107577401 hasLocation W21075774015 @default.
- W2107577401 hasLocation W21075774016 @default.
- W2107577401 hasOpenAccess W2107577401 @default.
- W2107577401 hasPrimaryLocation W21075774011 @default.
- W2107577401 hasRelatedWork W1557169263 @default.
- W2107577401 hasRelatedWork W1602801198 @default.
- W2107577401 hasRelatedWork W2038812594 @default.
- W2107577401 hasRelatedWork W2040868562 @default.
- W2107577401 hasRelatedWork W2088959497 @default.
- W2107577401 hasRelatedWork W2145546708 @default.
- W2107577401 hasRelatedWork W2146615705 @default.
- W2107577401 hasRelatedWork W2348361596 @default.
- W2107577401 hasRelatedWork W2358305873 @default.
- W2107577401 hasRelatedWork W426878624 @default.
- W2107577401 hasVolume "13" @default.
- W2107577401 isParatext "false" @default.
- W2107577401 isRetracted "false" @default.
- W2107577401 magId "2107577401" @default.
- W2107577401 workType "article" @default.