FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107645694> ?p ?o ?g. }

• W2107645694 endingPage "1219" @default.
• W2107645694 startingPage "1215" @default.
• W2107645694 abstract "Unexplained weight loss is common in patients with chronic obstructive pulmonary disease (COPD). Since leptin, an obesity gene product, is known to play important roles in the control of body weight and energy expenditure, we investigated serum leptin levels, along with circulating tumor necrosis factor-alpha (TNF-alpha) and soluble TNF receptor (sTNF-R55 and -R75) levels, in 31 patients with COPD and 15 age-matched healthy controls. The body mass index (BMI) and percent body fat (%fat) were significantly lower in the COPD patients than in the healthy controls (BMI = 18.1 +/- 2.7 kg/m2 versus 22.8 +/- 2.2 kg/m2 [mean +/- SD]; p < 0.0001; %fat = 16.9 +/- 5.8% versus 24.3 +/- 4.9%; p < 0.001). Serum leptin levels were significantly lower in the COPD patients than in the healthy controls (1.14 +/- 1.17 ng/ml versus 2.47 +/- 2.01 ng/ml; p < 0.05). In contrast, serum TNF-alpha levels (6.59 +/- 1.92 pg/ml versus 5.41 +/- 1.60 pg/ml; p < 0.05), plasma sTNF-R55 (1.16 +/- 0.47 ng/ml versus 0.67 +/- 0.13 ng/ml; p < 0.0001) and sTNF-R75 (3.65 +/- 1.29 ng/ml versus 2.25 +/- 0.43 ng/ml; p < 0.0001) levels were significantly higher in the COPD patients than in the healthy controls. Importantly, circulating leptin levels (log transformed) did correlate well with BMI and %fat, but not with TNF-alpha or with sTNF-R levels in the COPD patients. These data suggest that circulating leptin is independent of the TNF-alpha system and is regulated physiologically even in the presence of cachexia in patients with COPD." @default.
• W2107645694 created "2016-06-24" @default.
• W2107645694 creator A5001536372 @default.
• W2107645694 creator A5003232533 @default.
• W2107645694 creator A5003797388 @default.
• W2107645694 creator A5018970596 @default.
• W2107645694 creator A5029144756 @default.
• W2107645694 creator A5037418302 @default.
• W2107645694 creator A5064905150 @default.
• W2107645694 creator A5065417690 @default.
• W2107645694 date "1999-04-01" @default.
• W2107645694 modified "2023-10-16" @default.
• W2107645694 title "Circulating Leptin in Patients with Chronic Obstructive Pulmonary Disease" @default.
• W2107645694 cites W1590709474 @default.
• W2107645694 cites W1693798087 @default.
• W2107645694 cites W1921714027 @default.
• W2107645694 cites W1965860042 @default.
• W2107645694 cites W1977389491 @default.
• W2107645694 cites W1978345359 @default.
• W2107645694 cites W1987656388 @default.
• W2107645694 cites W1993203791 @default.
• W2107645694 cites W2005063633 @default.
• W2107645694 cites W2005926500 @default.
• W2107645694 cites W2014163208 @default.
• W2107645694 cites W2014444795 @default.
• W2107645694 cites W2015639803 @default.
• W2107645694 cites W2027998544 @default.
• W2107645694 cites W2031525111 @default.
• W2107645694 cites W2032295274 @default.
• W2107645694 cites W2039314937 @default.
• W2107645694 cites W2055072883 @default.
• W2107645694 cites W2063663267 @default.
• W2107645694 cites W2066781195 @default.
• W2107645694 cites W2066829964 @default.
• W2107645694 cites W2067813652 @default.
• W2107645694 cites W2070864665 @default.
• W2107645694 cites W2084397540 @default.
• W2107645694 cites W2086614008 @default.
• W2107645694 cites W2094989225 @default.
• W2107645694 cites W2101340193 @default.
• W2107645694 cites W2109555667 @default.
• W2107645694 cites W2120243498 @default.
• W2107645694 cites W2125510262 @default.
• W2107645694 cites W2129399962 @default.
• W2107645694 cites W2140597408 @default.
• W2107645694 cites W2144245161 @default.
• W2107645694 cites W2167628665 @default.
• W2107645694 cites W2171383864 @default.
• W2107645694 cites W2334337188 @default.
• W2107645694 cites W2342974898 @default.
• W2107645694 cites W2414581796 @default.
• W2107645694 cites W4230887170 @default.
• W2107645694 cites W4236577020 @default.
• W2107645694 cites W4236639597 @default.
• W2107645694 cites W4244059976 @default.
• W2107645694 cites W4245866536 @default.
• W2107645694 cites W4253342378 @default.
• W2107645694 doi "https://doi.org/10.1164/ajrccm.159.4.9806134" @default.
• W2107645694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10194168" @default.
• W2107645694 hasPublicationYear "1999" @default.
• W2107645694 type Work @default.
• W2107645694 sameAs 2107645694 @default.
• W2107645694 citedByCount "181" @default.
• W2107645694 countsByYear W21076456942012 @default.
• W2107645694 countsByYear W21076456942013 @default.
• W2107645694 countsByYear W21076456942014 @default.
• W2107645694 countsByYear W21076456942015 @default.
• W2107645694 countsByYear W21076456942016 @default.
• W2107645694 countsByYear W21076456942017 @default.
• W2107645694 countsByYear W21076456942018 @default.
• W2107645694 countsByYear W21076456942019 @default.
• W2107645694 countsByYear W21076456942020 @default.
• W2107645694 countsByYear W21076456942021 @default.
• W2107645694 countsByYear W21076456942022 @default.
• W2107645694 countsByYear W21076456942023 @default.
• W2107645694 crossrefType "journal-article" @default.
• W2107645694 hasAuthorship W2107645694A5001536372 @default.
• W2107645694 hasAuthorship W2107645694A5003232533 @default.
• W2107645694 hasAuthorship W2107645694A5003797388 @default.
• W2107645694 hasAuthorship W2107645694A5018970596 @default.
• W2107645694 hasAuthorship W2107645694A5029144756 @default.
• W2107645694 hasAuthorship W2107645694A5037418302 @default.
• W2107645694 hasAuthorship W2107645694A5064905150 @default.
• W2107645694 hasAuthorship W2107645694A5065417690 @default.
• W2107645694 hasConcept C126322002 @default.
• W2107645694 hasConcept C134018914 @default.
• W2107645694 hasConcept C17991360 @default.
• W2107645694 hasConcept C2776178081 @default.
• W2107645694 hasConcept C2776780178 @default.
• W2107645694 hasConcept C2777714996 @default.
• W2107645694 hasConcept C2780221984 @default.
• W2107645694 hasConcept C2780613262 @default.
• W2107645694 hasConcept C2780942790 @default.
• W2107645694 hasConcept C511355011 @default.
• W2107645694 hasConcept C71924100 @default.
• W2107645694 hasConceptScore W2107645694C126322002 @default.
• W2107645694 hasConceptScore W2107645694C134018914 @default.
• W2107645694 hasConceptScore W2107645694C17991360 @default.

• next