Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107698514> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2107698514 endingPage "219" @default.
- W2107698514 startingPage "207" @default.
- W2107698514 abstract "7 T(1;13)70H/+ and 13+/+ male mice were given 2 doses of 250 rad acute X-rays separated by 24 h. The +/+ mice were analysed in 2 groups during the first meiotic division for induced translocations, on average 177 and 233 days after irradiation, and the T70H/+ mice were analysed in parallel with the second group of +/+ males. One testis was treated with normal air-drying procedures yielding a random sample of cells. The other testis was processed according to a new technique, which enable separate analysis of the various locations along the seminiferous epithelium where groups of cells are synchronously in the diakinesis-metaphase I stage of meiosis. The number of cells in such groups was estimated. Both capita epididymes were used for a sperm count. In agreement with an earlier finding, fewer induced translocations were recovered from the T70H/+ mice than from +/+ mice (10.6 versus 19.2%, air-drying technique). Estimates of the group sizes in combination with the occurrence of induced translocations yielded the following information. A synchronously moving group of diakinesis-metaphase I cells originates from, on average, 1.25 stem cells (Appendix). We found an indication for a reduction in group size by 33% when a clone originated from a stem cell carrying an induced translocation compared with a wild-type clone (see Appendix). Both, the data on group size and the sperm counts indicate that, 7 months after the irradiation, the seminiferous epithelium has not totally recovered. Final recovery seems to be slower or absent in the T70H/+ males. The data obtained from the T70H/+ heterozygotes indicate the stem-cell spermatogonia to be responsible for the reduction of the rate or translocation induction with this karyotype, either due to a reduced formation rate or due to a diminished capacity of some of the induced translocation-carrying stem cells to proliferate into a clone reaching the meiotic divisions." @default.
- W2107698514 created "2016-06-24" @default.
- W2107698514 creator A5043662908 @default.
- W2107698514 creator A5076010133 @default.
- W2107698514 creator A5076781838 @default.
- W2107698514 date "1981-09-01" @default.
- W2107698514 modified "2023-10-17" @default.
- W2107698514 title "Clonal analysis of radiation-induced translocations in stem-cell spermatogonia of normal and T70H translocation heterozygous mice" @default.
- W2107698514 cites W1487908113 @default.
- W2107698514 cites W1494180256 @default.
- W2107698514 cites W1966751798 @default.
- W2107698514 cites W1969477574 @default.
- W2107698514 cites W1985743709 @default.
- W2107698514 cites W1986368616 @default.
- W2107698514 cites W1988030150 @default.
- W2107698514 cites W1992235183 @default.
- W2107698514 cites W2007306633 @default.
- W2107698514 cites W2018437991 @default.
- W2107698514 cites W2046275054 @default.
- W2107698514 cites W2051902571 @default.
- W2107698514 cites W2066688238 @default.
- W2107698514 cites W2091235724 @default.
- W2107698514 cites W2091685764 @default.
- W2107698514 cites W2093364385 @default.
- W2107698514 cites W2097987804 @default.
- W2107698514 cites W2132748776 @default.
- W2107698514 cites W2148139589 @default.
- W2107698514 cites W2153959891 @default.
- W2107698514 cites W2155218255 @default.
- W2107698514 doi "https://doi.org/10.1016/0027-5107(81)90006-3" @default.
- W2107698514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7300849" @default.
- W2107698514 hasPublicationYear "1981" @default.
- W2107698514 type Work @default.
- W2107698514 sameAs 2107698514 @default.
- W2107698514 citedByCount "9" @default.
- W2107698514 crossrefType "journal-article" @default.
- W2107698514 hasAuthorship W2107698514A5043662908 @default.
- W2107698514 hasAuthorship W2107698514A5076010133 @default.
- W2107698514 hasAuthorship W2107698514A5076781838 @default.
- W2107698514 hasConcept C104317684 @default.
- W2107698514 hasConcept C138626823 @default.
- W2107698514 hasConcept C148196450 @default.
- W2107698514 hasConcept C153911025 @default.
- W2107698514 hasConcept C16685009 @default.
- W2107698514 hasConcept C2781087480 @default.
- W2107698514 hasConcept C28328180 @default.
- W2107698514 hasConcept C30481170 @default.
- W2107698514 hasConcept C54355233 @default.
- W2107698514 hasConcept C70278784 @default.
- W2107698514 hasConcept C71924100 @default.
- W2107698514 hasConcept C81089528 @default.
- W2107698514 hasConcept C86803240 @default.
- W2107698514 hasConceptScore W2107698514C104317684 @default.
- W2107698514 hasConceptScore W2107698514C138626823 @default.
- W2107698514 hasConceptScore W2107698514C148196450 @default.
- W2107698514 hasConceptScore W2107698514C153911025 @default.
- W2107698514 hasConceptScore W2107698514C16685009 @default.
- W2107698514 hasConceptScore W2107698514C2781087480 @default.
- W2107698514 hasConceptScore W2107698514C28328180 @default.
- W2107698514 hasConceptScore W2107698514C30481170 @default.
- W2107698514 hasConceptScore W2107698514C54355233 @default.
- W2107698514 hasConceptScore W2107698514C70278784 @default.
- W2107698514 hasConceptScore W2107698514C71924100 @default.
- W2107698514 hasConceptScore W2107698514C81089528 @default.
- W2107698514 hasConceptScore W2107698514C86803240 @default.
- W2107698514 hasIssue "2" @default.
- W2107698514 hasLocation W21076985141 @default.
- W2107698514 hasLocation W21076985142 @default.
- W2107698514 hasOpenAccess W2107698514 @default.
- W2107698514 hasPrimaryLocation W21076985141 @default.
- W2107698514 hasRelatedWork W2011105529 @default.
- W2107698514 hasRelatedWork W2033959934 @default.
- W2107698514 hasRelatedWork W2107698514 @default.
- W2107698514 hasRelatedWork W2143346382 @default.
- W2107698514 hasRelatedWork W2146790633 @default.
- W2107698514 hasRelatedWork W2155327507 @default.
- W2107698514 hasRelatedWork W2169559709 @default.
- W2107698514 hasRelatedWork W2186563013 @default.
- W2107698514 hasRelatedWork W2532978894 @default.
- W2107698514 hasRelatedWork W2092874662 @default.
- W2107698514 hasVolume "83" @default.
- W2107698514 isParatext "false" @default.
- W2107698514 isRetracted "false" @default.
- W2107698514 magId "2107698514" @default.
- W2107698514 workType "article" @default.