FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107699001> ?p ?o ?g. }

• W2107699001 endingPage "1582" @default.
• W2107699001 startingPage "1569" @default.
• W2107699001 abstract "Summary The induction of Bacillus subtilis genes controlled by the extracytoplasmic function alternative sigma factor σ W is strongly impaired in a strain deleted for the ClpP peptidase gene and in a double knockout of the ClpX and ClpE ATPase genes. Truncated soluble forms of the σ W anti‐sigma factor RsiW are stabilized in a clpP minus strain as revealed by the green fluorescent reporter protein fused to the N‐terminus of RsiW and by pulse‐chase experiments. Conserved alanine residues are present in the transmembrane region of RsiW, and mutations in these positions abolish induction of σ W ‐controlled genes. Following alkaline shock, a truncated cytoplasmic form of RsiW is detectable in a strain expressing a triple alanine mutant allele of rsiW . These data point to a mechanism where the trans ‐membrane segment of RsiW contains a cryptic proteolytic tag that is uncovered as a result of intramembrane proteolysis of RsiW by RasP (YluC). After RasP‐clipped RsiW is detached from the membrane, this proteolytic tag becomes crucial for the complete degradation of RsiW by cytoplasmic proteases and the release of σ W . ClpXP plays a major role in this third proteolytic step of stress‐induced degradation of RsiW. Overexpression of SsrA‐tagged green fluorescent protein as a ClpXP substrate protein reduces alkali induction of a σ W ‐controlled gene by a factor of about three, indicating that a titration mechanism is able to tune the σ W ‐mediated stress response to the cellular state." @default.
• W2107699001 created "2016-06-24" @default.
• W2107699001 creator A5006016288 @default.
• W2107699001 creator A5008389029 @default.
• W2107699001 creator A5053764065 @default.
• W2107699001 date "2006-08-08" @default.
• W2107699001 modified "2023-10-04" @default.
• W2107699001 title "Involvement of Clp protease activity in modulating the Bacillus subtilis ?^Wstress response" @default.
• W2107699001 cites W1527050015 @default.
• W2107699001 cites W1536772488 @default.
• W2107699001 cites W1539516473 @default.
• W2107699001 cites W1558571934 @default.
• W2107699001 cites W1569886462 @default.
• W2107699001 cites W1845220076 @default.
• W2107699001 cites W1863386058 @default.
• W2107699001 cites W1883026703 @default.
• W2107699001 cites W1909878702 @default.
• W2107699001 cites W1964118366 @default.
• W2107699001 cites W1967824952 @default.
• W2107699001 cites W2006395260 @default.
• W2107699001 cites W2012630600 @default.
• W2107699001 cites W2013882590 @default.
• W2107699001 cites W2016848577 @default.
• W2107699001 cites W2019623096 @default.
• W2107699001 cites W2029480898 @default.
• W2107699001 cites W2031790892 @default.
• W2107699001 cites W2033565485 @default.
• W2107699001 cites W2038663142 @default.
• W2107699001 cites W2038897801 @default.
• W2107699001 cites W2041431215 @default.
• W2107699001 cites W2050642108 @default.
• W2107699001 cites W2056552659 @default.
• W2107699001 cites W2068166540 @default.
• W2107699001 cites W2081801019 @default.
• W2107699001 cites W2086590919 @default.
• W2107699001 cites W2098570486 @default.
• W2107699001 cites W2100975834 @default.
• W2107699001 cites W2104815620 @default.
• W2107699001 cites W2114878533 @default.
• W2107699001 cites W2115703815 @default.
• W2107699001 cites W2116572617 @default.
• W2107699001 cites W2123802756 @default.
• W2107699001 cites W2124949743 @default.
• W2107699001 cites W2125273006 @default.
• W2107699001 cites W2127597865 @default.
• W2107699001 cites W2131342761 @default.
• W2107699001 cites W2134331533 @default.
• W2107699001 cites W2144010612 @default.
• W2107699001 cites W2144047169 @default.
• W2107699001 cites W2147057508 @default.
• W2107699001 cites W2151980833 @default.
• W2107699001 cites W2162222463 @default.
• W2107699001 cites W4241640895 @default.
• W2107699001 doi "https://doi.org/10.1111/j.1365-2958.2006.05323.x" @default.
• W2107699001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16899079" @default.
• W2107699001 hasPublicationYear "2006" @default.
• W2107699001 type Work @default.
• W2107699001 sameAs 2107699001 @default.
• W2107699001 citedByCount "77" @default.
• W2107699001 countsByYear W21076990012012 @default.
• W2107699001 countsByYear W21076990012013 @default.
• W2107699001 countsByYear W21076990012014 @default.
• W2107699001 countsByYear W21076990012015 @default.
• W2107699001 countsByYear W21076990012016 @default.
• W2107699001 countsByYear W21076990012017 @default.
• W2107699001 countsByYear W21076990012018 @default.
• W2107699001 countsByYear W21076990012019 @default.
• W2107699001 countsByYear W21076990012020 @default.
• W2107699001 countsByYear W21076990012021 @default.
• W2107699001 countsByYear W21076990012022 @default.
• W2107699001 countsByYear W21076990012023 @default.
• W2107699001 crossrefType "journal-article" @default.
• W2107699001 hasAuthorship W2107699001A5006016288 @default.
• W2107699001 hasAuthorship W2107699001A5008389029 @default.
• W2107699001 hasAuthorship W2107699001A5053764065 @default.
• W2107699001 hasConcept C101635128 @default.
• W2107699001 hasConcept C101762097 @default.
• W2107699001 hasConcept C104317684 @default.
• W2107699001 hasConcept C143065580 @default.
• W2107699001 hasConcept C150194340 @default.
• W2107699001 hasConcept C153911025 @default.
• W2107699001 hasConcept C170493617 @default.
• W2107699001 hasConcept C181199279 @default.
• W2107699001 hasConcept C182220744 @default.
• W2107699001 hasConcept C190062978 @default.
• W2107699001 hasConcept C23265538 @default.
• W2107699001 hasConcept C24530287 @default.
• W2107699001 hasConcept C2776714187 @default.
• W2107699001 hasConcept C2777272437 @default.
• W2107699001 hasConcept C2781307694 @default.
• W2107699001 hasConcept C47319516 @default.
• W2107699001 hasConcept C523546767 @default.
• W2107699001 hasConcept C54355233 @default.
• W2107699001 hasConcept C55493867 @default.
• W2107699001 hasConcept C86803240 @default.
• W2107699001 hasConcept C95444343 @default.
• W2107699001 hasConceptScore W2107699001C101635128 @default.
• W2107699001 hasConceptScore W2107699001C101762097 @default.

• next