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- W2107786601 abstract "Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is responsible for SARS infection. Nucleocapsid (N) protein of SARS-CoV encapsidates the viral RNA and plays an important role in virus particle assembly and release. In this study, the N protein of SARS-CoV was found to associate with B23, a phosphoprotein in nucleolus, in vitro and in vivo. Mapping studies localized the critical N sequences for this interaction to amino acid residues 175–210, which included a serine/arginine (SR)-rich domain. In vitro phosphorylation assay showed that the N protein inhibited the B23 phosphorylation at Thr199." @default.
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- W2107786601 date "2008-05-01" @default.
- W2107786601 modified "2023-09-28" @default.
- W2107786601 title "The nucleocapsid protein of SARS-associated coronavirus inhibits B23 phosphorylation" @default.
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- W2107786601 doi "https://doi.org/10.1016/j.bbrc.2008.01.096" @default.
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