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- W2107848765 abstract "An ideal vector in gene therapy should exhibit high serum stability, excellent biocompatibility, a desired transfection efficacy and permeability into targeted tissues. Here, we describe a class of low-molecular-weight fluorodendrimers for efficient gene delivery. These materials self-assemble into uniform nanospheres and allow for efficient transfection at low charge ratios and very low DNA doses with minimal cytotoxicity. Our results demonstrate that these vectors combine the features of synthetic gene vectors such as liposomes and cationic polymers and present promising potential for clinical gene therapy." @default.
- W2107848765 created "2016-06-24" @default.
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- W2107848765 date "2015-08-10" @default.
- W2107848765 modified "2023-10-16" @default.
- W2107848765 title "Self‐Assembled Fluorodendrimers Combine the Features of Lipid and Polymeric Vectors in Gene Delivery" @default.
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- W2107848765 doi "https://doi.org/10.1002/anie.201501461" @default.
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