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- W2107852010 abstract "The purpose of this study was to examine the allometric analyses of marbofloxacin, moxifloxacin, danofloxacin and difloxacin using pharmacokinetic data from the literature. The parameters of interest (half‐life, clearance and volume of distribution) were correlated across species as a function of body weight using an allometric approach ( Y = aW b ). Results of the allometric analysis indicated similarity between clearance and volume of distribution as they relate to body weight for all drugs. The elimination half‐life was independent of body mass for all fluoroquinolones except moxifloxacin. Results of the analysis suggest that allometric scaling can be used as a tool for predicting pharmacokinetic parameters for fluoroquinolones." @default.
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- W2107852010 date "2007-07-23" @default.
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- W2107852010 title "Allometric scaling of marbofloxacin, moxifloxacin, danofloxacin and difloxacin pharmacokinetics: a retrospective analysis" @default.
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- W2107852010 doi "https://doi.org/10.1111/j.1365-2885.2007.00886.x" @default.
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