FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107890915> ?p ?o ?g. }

• W2107890915 abstract "To evaluate patient selection criteria, methodology, safety and clinical outcomes of stereotactic body radiotherapy (SBRT) for treatment of vertebral metastases.Eight centers from the United States (n=5), Canada (n=2) and Germany (n=1) participated in the retrospective study and analyzed 301 patients with 387 vertebral metastases. No patient had been exposed to prior radiation at the treatment site. All patients were treated with linac-based SBRT using cone-beam CT image-guidance and online correction of set-up errors in six degrees of freedom.387 spinal metastases were treated and the median follow-up was 11.8 months. The median number of consecutive vertebrae treated in a single volume was one (range, 1-6), and the median total dose was 24 Gy (range 8-60 Gy) in 3 fractions (range 1-20). The median EQD210 was 38 Gy (range 12-81 Gy). Median overall survival (OS) was 19.5 months and local tumor control (LC) at two years was 83.9%. On multivariate analysis for OS, male sex (p<0.001; HR=0.44), performance status <90 (p<0.001; HR=0.46), presence of visceral metastases (p=0.007; HR=0.50), uncontrolled systemic disease (p=0.007; HR=0.45), >1 vertebra treated with SBRT (p=0.04; HR=0.62) were correlated with worse outcomes. For LC, an interval between primary diagnosis of cancer and SBRT of ≤ 30 months (p=0.01; HR=0.27) and histology of primary disease (NSCLC, renal cell cancer, melanoma, other) (p=0.01; HR=0.21) were correlated with worse LC. Vertebral compression fractures progressed and developed de novo in 4.1% and 3.6%, respectively. Other adverse events were rare and no radiation induced myelopathy reported.This multi-institutional cohort study reports high rates of efficacy with spine SBRT. At this time the optimal fractionation within high dose practice is unknown." @default.
• W2107890915 created "2016-06-24" @default.
• W2107890915 creator A5001384287 @default.
• W2107890915 creator A5003967834 @default.
• W2107890915 creator A5004824920 @default.
• W2107890915 creator A5015138770 @default.
• W2107890915 creator A5017468691 @default.
• W2107890915 creator A5023510680 @default.
• W2107890915 creator A5025335132 @default.
• W2107890915 creator A5029207414 @default.
• W2107890915 creator A5043879863 @default.
• W2107890915 creator A5044374896 @default.
• W2107890915 creator A5063267716 @default.
• W2107890915 creator A5063901580 @default.
• W2107890915 creator A5080794668 @default.
• W2107890915 date "2014-10-16" @default.
• W2107890915 modified "2023-10-17" @default.
• W2107890915 title "Safety and efficacy of stereotactic body radiotherapy as primary treatment for vertebral metastases: a multi-institutional analysis" @default.
• W2107890915 cites W1515042192 @default.
• W2107890915 cites W1570829890 @default.
• W2107890915 cites W1589157904 @default.
• W2107890915 cites W1823223265 @default.
• W2107890915 cites W1946825180 @default.
• W2107890915 cites W1976883212 @default.
• W2107890915 cites W1977465552 @default.
• W2107890915 cites W1988227247 @default.
• W2107890915 cites W1992007584 @default.
• W2107890915 cites W1993494057 @default.
• W2107890915 cites W1994009716 @default.
• W2107890915 cites W1999874349 @default.
• W2107890915 cites W2005638449 @default.
• W2107890915 cites W2009202244 @default.
• W2107890915 cites W2013490582 @default.
• W2107890915 cites W2018038855 @default.
• W2107890915 cites W2022441355 @default.
• W2107890915 cites W2023987851 @default.
• W2107890915 cites W2025110241 @default.
• W2107890915 cites W2040112669 @default.
• W2107890915 cites W2042444022 @default.
• W2107890915 cites W2047058530 @default.
• W2107890915 cites W2047842438 @default.
• W2107890915 cites W2054974480 @default.
• W2107890915 cites W2069641832 @default.
• W2107890915 cites W2091387599 @default.
• W2107890915 cites W2104701073 @default.
• W2107890915 cites W2108145085 @default.
• W2107890915 cites W2110069491 @default.
• W2107890915 cites W2110996227 @default.
• W2107890915 cites W2113235727 @default.
• W2107890915 cites W2128150701 @default.
• W2107890915 cites W2130693156 @default.
• W2107890915 cites W2136392842 @default.
• W2107890915 cites W2140902814 @default.
• W2107890915 cites W2143853878 @default.
• W2107890915 cites W2169751903 @default.
• W2107890915 cites W2171155897 @default.
• W2107890915 cites W4255489545 @default.
• W2107890915 doi "https://doi.org/10.1186/s13014-014-0226-2" @default.
• W2107890915 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4205292" @default.
• W2107890915 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25319530" @default.
• W2107890915 hasPublicationYear "2014" @default.
• W2107890915 type Work @default.
• W2107890915 sameAs 2107890915 @default.
• W2107890915 citedByCount "140" @default.
• W2107890915 countsByYear W21078909152015 @default.
• W2107890915 countsByYear W21078909152016 @default.
• W2107890915 countsByYear W21078909152017 @default.
• W2107890915 countsByYear W21078909152018 @default.
• W2107890915 countsByYear W21078909152019 @default.
• W2107890915 countsByYear W21078909152020 @default.
• W2107890915 countsByYear W21078909152021 @default.
• W2107890915 countsByYear W21078909152022 @default.
• W2107890915 countsByYear W21078909152023 @default.
• W2107890915 crossrefType "journal-article" @default.
• W2107890915 hasAuthorship W2107890915A5001384287 @default.
• W2107890915 hasAuthorship W2107890915A5003967834 @default.
• W2107890915 hasAuthorship W2107890915A5004824920 @default.
• W2107890915 hasAuthorship W2107890915A5015138770 @default.
• W2107890915 hasAuthorship W2107890915A5017468691 @default.
• W2107890915 hasAuthorship W2107890915A5023510680 @default.
• W2107890915 hasAuthorship W2107890915A5025335132 @default.
• W2107890915 hasAuthorship W2107890915A5029207414 @default.
• W2107890915 hasAuthorship W2107890915A5043879863 @default.
• W2107890915 hasAuthorship W2107890915A5044374896 @default.
• W2107890915 hasAuthorship W2107890915A5063267716 @default.
• W2107890915 hasAuthorship W2107890915A5063901580 @default.
• W2107890915 hasAuthorship W2107890915A5080794668 @default.
• W2107890915 hasBestOaLocation W21078909151 @default.
• W2107890915 hasConcept C126322002 @default.
• W2107890915 hasConcept C126838900 @default.
• W2107890915 hasConcept C141071460 @default.
• W2107890915 hasConcept C167135981 @default.
• W2107890915 hasConcept C2780387249 @default.
• W2107890915 hasConcept C2989005 @default.
• W2107890915 hasConcept C38180746 @default.
• W2107890915 hasConcept C509974204 @default.
• W2107890915 hasConcept C71924100 @default.
• W2107890915 hasConceptScore W2107890915C126322002 @default.
• W2107890915 hasConceptScore W2107890915C126838900 @default.
• W2107890915 hasConceptScore W2107890915C141071460 @default.

• next