FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107934345> ?p ?o ?g. }

• W2107934345 endingPage "478" @default.
• W2107934345 startingPage "471" @default.
• W2107934345 abstract "In patients with inflammatory myopathy and dysphagia, our aims were to determine: (1) the diagnostic utility of clinical and laboratory indicators; (2) the biomechanical properties of the pharyngo-oesophageal segment; (3) the usefulness of pharyngeal videomanometry in distinguishing neuropathic from myopathic dysphagia; and (4) clinical outcome.Clinical, laboratory, and videomanometric assessment was performed in 13 patients with myositis and dysphagia, in 17 disease controls with dysphagia (due to proven CNS disease), and in 22 healthy age matched controls. The diagnostic accuracy of creatine kinase (CPK), erythrocyte sedimentation rate, antinuclear antibody, and electromyography (EMG) were compared with the gold standard muscle biopsy. The biomechanical properties of the pharyngo-oesophageal segment were assessed by videomanometry.Mean time from dysphagia onset to the diagnosis of myositis was 55 months (range 1-180). One third had no extrapharyngeal muscle weakness; 25% had normal CPK, and EMG was unhelpful in 28%. Compared with neurogenic controls, myositis patients had more prevalent cricopharyngeal restrictive disorders (69% v 14%; p=0.0003), reduced upper oesophageal sphincter (UOS) opening (p=0.01), and elevated hypopharyngeal intrabolus pressures (p=0.001). Videomanometric features favouring a myopathic over a neuropathic aetiology were: preserved pharyngeal swallow response, complete UOS relaxation, and normal swallow coordination. The 12 month mortality was 31%.The notable lack of supportive clinical signs and significant false negative rates for laboratory tests contribute to the marked delay in diagnosis. The myopathic process is strongly associated with restricted sphincter opening suggesting that cricopharyngeal disruption is a useful adjunct to immunosuppressive therapy. The condition has a poor prognosis." @default.
• W2107934345 created "2016-06-24" @default.
• W2107934345 creator A5007241984 @default.
• W2107934345 creator A5007573856 @default.
• W2107934345 creator A5054734081 @default.
• W2107934345 creator A5063069868 @default.
• W2107934345 creator A5064688280 @default.
• W2107934345 date "2003-04-01" @default.
• W2107934345 modified "2023-09-27" @default.
• W2107934345 title "Biomechanics, diagnosis, and treatment outcome in inflammatory myopathy presenting as oropharyngeal dysphagia" @default.
• W2107934345 cites W1705986225 @default.
• W2107934345 cites W1841211243 @default.
• W2107934345 cites W1885846526 @default.
• W2107934345 cites W1967848078 @default.
• W2107934345 cites W1974076742 @default.
• W2107934345 cites W1990649091 @default.
• W2107934345 cites W1997532070 @default.
• W2107934345 cites W2008024632 @default.
• W2107934345 cites W2010210890 @default.
• W2107934345 cites W203522410 @default.
• W2107934345 cites W2041037194 @default.
• W2107934345 cites W2056543374 @default.
• W2107934345 cites W2056882838 @default.
• W2107934345 cites W2059003430 @default.
• W2107934345 cites W2070113718 @default.
• W2107934345 cites W2103599363 @default.
• W2107934345 cites W2110083315 @default.
• W2107934345 cites W2128778082 @default.
• W2107934345 cites W2132830969 @default.
• W2107934345 cites W2153858571 @default.
• W2107934345 cites W2157803408 @default.
• W2107934345 cites W2338321070 @default.
• W2107934345 cites W2430953019 @default.
• W2107934345 cites W34911563 @default.
• W2107934345 cites W3022664073 @default.
• W2107934345 doi "https://doi.org/10.1136/gut.52.4.471" @default.
• W2107934345 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1773618" @default.
• W2107934345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12631653" @default.
• W2107934345 hasPublicationYear "2003" @default.
• W2107934345 type Work @default.
• W2107934345 sameAs 2107934345 @default.
• W2107934345 citedByCount "81" @default.
• W2107934345 countsByYear W21079343452012 @default.
• W2107934345 countsByYear W21079343452013 @default.
• W2107934345 countsByYear W21079343452014 @default.
• W2107934345 countsByYear W21079343452015 @default.
• W2107934345 countsByYear W21079343452016 @default.
• W2107934345 countsByYear W21079343452017 @default.
• W2107934345 countsByYear W21079343452018 @default.
• W2107934345 countsByYear W21079343452019 @default.
• W2107934345 countsByYear W21079343452020 @default.
• W2107934345 countsByYear W21079343452021 @default.
• W2107934345 countsByYear W21079343452022 @default.
• W2107934345 countsByYear W21079343452023 @default.
• W2107934345 crossrefType "journal-article" @default.
• W2107934345 hasAuthorship W2107934345A5007241984 @default.
• W2107934345 hasAuthorship W2107934345A5007573856 @default.
• W2107934345 hasAuthorship W2107934345A5054734081 @default.
• W2107934345 hasAuthorship W2107934345A5063069868 @default.
• W2107934345 hasAuthorship W2107934345A5064688280 @default.
• W2107934345 hasBestOaLocation W21079343451 @default.
• W2107934345 hasConcept C112497637 @default.
• W2107934345 hasConcept C126322002 @default.
• W2107934345 hasConcept C141071460 @default.
• W2107934345 hasConcept C2775934546 @default.
• W2107934345 hasConcept C2776717089 @default.
• W2107934345 hasConcept C2777300911 @default.
• W2107934345 hasConcept C2777327098 @default.
• W2107934345 hasConcept C2777515770 @default.
• W2107934345 hasConcept C2779999465 @default.
• W2107934345 hasConcept C2780181341 @default.
• W2107934345 hasConcept C2780247198 @default.
• W2107934345 hasConcept C2780596822 @default.
• W2107934345 hasConcept C2781232998 @default.
• W2107934345 hasConcept C71924100 @default.
• W2107934345 hasConcept C90924648 @default.
• W2107934345 hasConcept C99508421 @default.
• W2107934345 hasConceptScore W2107934345C112497637 @default.
• W2107934345 hasConceptScore W2107934345C126322002 @default.
• W2107934345 hasConceptScore W2107934345C141071460 @default.
• W2107934345 hasConceptScore W2107934345C2775934546 @default.
• W2107934345 hasConceptScore W2107934345C2776717089 @default.
• W2107934345 hasConceptScore W2107934345C2777300911 @default.
• W2107934345 hasConceptScore W2107934345C2777327098 @default.
• W2107934345 hasConceptScore W2107934345C2777515770 @default.
• W2107934345 hasConceptScore W2107934345C2779999465 @default.
• W2107934345 hasConceptScore W2107934345C2780181341 @default.
• W2107934345 hasConceptScore W2107934345C2780247198 @default.
• W2107934345 hasConceptScore W2107934345C2780596822 @default.
• W2107934345 hasConceptScore W2107934345C2781232998 @default.
• W2107934345 hasConceptScore W2107934345C71924100 @default.
• W2107934345 hasConceptScore W2107934345C90924648 @default.
• W2107934345 hasConceptScore W2107934345C99508421 @default.
• W2107934345 hasIssue "4" @default.
• W2107934345 hasLocation W21079343451 @default.
• W2107934345 hasLocation W21079343452 @default.
• W2107934345 hasLocation W21079343453 @default.
• W2107934345 hasLocation W21079343454 @default.

• next