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- W2107935250 endingPage "R37" @default.
- W2107935250 startingPage "R37" @default.
- W2107935250 abstract "One of the major genomics challenges is to better understand how correct gene expression is orchestrated. Recent studies have shown how spatial chromatin organization is critical in the regulation of gene expression. Here, we developed a suite of computer programs to identify chromatin conformation signatures with 5C technology http://Dostielab.biochem.mcgill.ca . We identified dynamic HoxA cluster chromatin conformation signatures associated with cellular differentiation. Genome-wide chromatin conformation signature identification might uniquely identify disease-associated states and represent an entirely novel class of human disease biomarkers." @default.
- W2107935250 created "2016-06-24" @default.
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- W2107935250 date "2009-01-01" @default.
- W2107935250 modified "2023-10-13" @default.
- W2107935250 title "Chromatin conformation signatures of cellular differentiation" @default.
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- W2107935250 doi "https://doi.org/10.1186/gb-2009-10-4-r37" @default.
- W2107935250 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2688928" @default.
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