Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107942449> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2107942449 abstract "Peritoneal adhesions prevention. Neurokinin-1 receptor antagonist Background: The fibrinolytic activity plays an important role in Peritoneal Adhesions (PA) develop - ment. Its well known that de substance P decreased the fibrinolysis by binding the neurokinin-1 receptor, improving the PA formation. Objectives: To evaluate the effectiveness of intraperitoneal treatment with a Neurokinin-1 receptor antagonist (NK-R1A) in peritoneal adhesion prevention in animal model. Materials and Methods: In 40 male wistar rats, PA were induced, and then randomly assigned to 2 groups: A group treated with Aprepitant (NK-R1A), and a control group. The animals were killed at 7 or 14 postoperative day, and the number, severity and histopathology of PA were evaluated. Results: NK-R1A decreased the number (40% less) and severity (p = 0.001) of PA when compare to control group. The NK-R1A group had less PA in manipulated and no manipulated organs during surgery. Besides presented less fibrosis (p = 0.001), less inflamation (p = 0.005) and less vascular proliferation (p = 0.047) than control group. Conclusions: The NK- R1A is effective as in PA prevention." @default.
- W2107942449 created "2016-06-24" @default.
- W2107942449 creator A5013483594 @default.
- W2107942449 creator A5021170537 @default.
- W2107942449 creator A5023217772 @default.
- W2107942449 creator A5036814543 @default.
- W2107942449 creator A5075979184 @default.
- W2107942449 creator A5085834919 @default.
- W2107942449 date "2010-08-01" @default.
- W2107942449 modified "2023-09-28" @default.
- W2107942449 title "Prevención de adherencias peritoneales postoperatorias mediante uso de antagonista de receptores de neurokinina tipo 1" @default.
- W2107942449 cites W145196012 @default.
- W2107942449 cites W1611331702 @default.
- W2107942449 cites W1976259402 @default.
- W2107942449 cites W1983869449 @default.
- W2107942449 cites W1986512466 @default.
- W2107942449 cites W1994018944 @default.
- W2107942449 cites W1995027914 @default.
- W2107942449 cites W2010940461 @default.
- W2107942449 cites W2018809558 @default.
- W2107942449 cites W2021190023 @default.
- W2107942449 cites W2036674445 @default.
- W2107942449 cites W2054550088 @default.
- W2107942449 cites W2063846872 @default.
- W2107942449 cites W2070971340 @default.
- W2107942449 cites W2071973910 @default.
- W2107942449 cites W2074865203 @default.
- W2107942449 cites W2078268950 @default.
- W2107942449 cites W2078604158 @default.
- W2107942449 cites W2085556238 @default.
- W2107942449 cites W2100831089 @default.
- W2107942449 cites W2120274577 @default.
- W2107942449 cites W2135788850 @default.
- W2107942449 cites W2149644604 @default.
- W2107942449 cites W2154784975 @default.
- W2107942449 cites W2217593400 @default.
- W2107942449 cites W2257002533 @default.
- W2107942449 doi "https://doi.org/10.4067/s0718-40262010000400008" @default.
- W2107942449 hasPublicationYear "2010" @default.
- W2107942449 type Work @default.
- W2107942449 sameAs 2107942449 @default.
- W2107942449 citedByCount "1" @default.
- W2107942449 countsByYear W21079424492016 @default.
- W2107942449 crossrefType "journal-article" @default.
- W2107942449 hasAuthorship W2107942449A5013483594 @default.
- W2107942449 hasAuthorship W2107942449A5021170537 @default.
- W2107942449 hasAuthorship W2107942449A5023217772 @default.
- W2107942449 hasAuthorship W2107942449A5036814543 @default.
- W2107942449 hasAuthorship W2107942449A5075979184 @default.
- W2107942449 hasAuthorship W2107942449A5085834919 @default.
- W2107942449 hasBestOaLocation W21079424491 @default.
- W2107942449 hasConcept C71924100 @default.
- W2107942449 hasConceptScore W2107942449C71924100 @default.
- W2107942449 hasIssue "4" @default.
- W2107942449 hasLocation W21079424491 @default.
- W2107942449 hasLocation W21079424492 @default.
- W2107942449 hasOpenAccess W2107942449 @default.
- W2107942449 hasPrimaryLocation W21079424491 @default.
- W2107942449 hasRelatedWork W1506200166 @default.
- W2107942449 hasRelatedWork W1995515455 @default.
- W2107942449 hasRelatedWork W2039318446 @default.
- W2107942449 hasRelatedWork W2048182022 @default.
- W2107942449 hasRelatedWork W2080531066 @default.
- W2107942449 hasRelatedWork W2748952813 @default.
- W2107942449 hasRelatedWork W2899084033 @default.
- W2107942449 hasRelatedWork W3031052312 @default.
- W2107942449 hasRelatedWork W3032375762 @default.
- W2107942449 hasRelatedWork W3108674512 @default.
- W2107942449 hasVolume "62" @default.
- W2107942449 isParatext "false" @default.
- W2107942449 isRetracted "false" @default.
- W2107942449 magId "2107942449" @default.
- W2107942449 workType "article" @default.