FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2107946144> ?p ?o ?g. }

• W2107946144 endingPage "301" @default.
• W2107946144 startingPage "295" @default.
• W2107946144 abstract "FADD is an important proapoptotic adaptor in death receptor-induced apoptosis. Recently, FADD has been found to participate in a variety of non-apoptotic processes, such as development, cell cycle progression and survival. Its non-apoptotic activities were regulated by the phosphorylated status of the serine residue located at the C-terminal region, a domain distinct from the proapoptotic function related DED and DD domains. However, due to the difficulties in expression and crystallization of natural FADD, by far the molecular structures of all FADD variants did not contain the C-terminal region. To elucidate the structure-function relationship of C-terminal region, we need to obtain an FADD variant that containing C-terminal region. In this study, mouse FADD (80-205) containing DD domain and C-terminal region, designated as C-FADD, was expressed in E. coli with His-tag at the N-terminus and purified by Ni2+ affinity chromatography. The purified protein existed as a homogenous monomer in glutaraldehyde cross-linking analysis and exhibited a typical α-helix spectrum in CD (circular dichroism) assay. In vitro His-tag pull-down assay demonstrated that the purified C-FADD possessed the CK Iα-binding activity which was important for its non-apoptotic function." @default.
• W2107946144 created "2016-06-24" @default.
• W2107946144 creator A5018244700 @default.
• W2107946144 creator A5036921991 @default.
• W2107946144 creator A5036930387 @default.
• W2107946144 creator A5059294101 @default.
• W2107946144 creator A5059618475 @default.
• W2107946144 creator A5059686406 @default.
• W2107946144 creator A5060348081 @default.
• W2107946144 creator A5065620185 @default.
• W2107946144 creator A5072346942 @default.
• W2107946144 creator A5086888914 @default.
• W2107946144 creator A5087135939 @default.
• W2107946144 date "2009-08-01" @default.
• W2107946144 modified "2023-09-27" @default.
• W2107946144 title "Expression, Purification and Characterization of C-FADD" @default.
• W2107946144 cites W1503848289 @default.
• W2107946144 cites W1616910822 @default.
• W2107946144 cites W1848662104 @default.
• W2107946144 cites W1911239883 @default.
• W2107946144 cites W1962507920 @default.
• W2107946144 cites W1967894078 @default.
• W2107946144 cites W1968328677 @default.
• W2107946144 cites W1983750488 @default.
• W2107946144 cites W1986308149 @default.
• W2107946144 cites W1987675396 @default.
• W2107946144 cites W1989235336 @default.
• W2107946144 cites W1989474275 @default.
• W2107946144 cites W1995871393 @default.
• W2107946144 cites W1999710434 @default.
• W2107946144 cites W2004511841 @default.
• W2107946144 cites W2010957706 @default.
• W2107946144 cites W2020576522 @default.
• W2107946144 cites W2025128734 @default.
• W2107946144 cites W2027946516 @default.
• W2107946144 cites W2029501678 @default.
• W2107946144 cites W2029721783 @default.
• W2107946144 cites W2038520262 @default.
• W2107946144 cites W2038974287 @default.
• W2107946144 cites W2058855556 @default.
• W2107946144 cites W2066274736 @default.
• W2107946144 cites W2113414525 @default.
• W2107946144 cites W2122482353 @default.
• W2107946144 cites W2127621359 @default.
• W2107946144 cites W2143680039 @default.
• W2107946144 cites W2150536749 @default.
• W2107946144 cites W2154949807 @default.
• W2107946144 doi "https://doi.org/10.1038/cmi.2009.39" @default.
• W2107946144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4002721" @default.
• W2107946144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19728931" @default.
• W2107946144 hasPublicationYear "2009" @default.
• W2107946144 type Work @default.
• W2107946144 sameAs 2107946144 @default.
• W2107946144 citedByCount "7" @default.
• W2107946144 countsByYear W21079461442012 @default.
• W2107946144 countsByYear W21079461442017 @default.
• W2107946144 countsByYear W21079461442018 @default.
• W2107946144 countsByYear W21079461442021 @default.
• W2107946144 crossrefType "journal-article" @default.
• W2107946144 hasAuthorship W2107946144A5018244700 @default.
• W2107946144 hasAuthorship W2107946144A5036921991 @default.
• W2107946144 hasAuthorship W2107946144A5036930387 @default.
• W2107946144 hasAuthorship W2107946144A5059294101 @default.
• W2107946144 hasAuthorship W2107946144A5059618475 @default.
• W2107946144 hasAuthorship W2107946144A5059686406 @default.
• W2107946144 hasAuthorship W2107946144A5060348081 @default.
• W2107946144 hasAuthorship W2107946144A5065620185 @default.
• W2107946144 hasAuthorship W2107946144A5072346942 @default.
• W2107946144 hasAuthorship W2107946144A5086888914 @default.
• W2107946144 hasAuthorship W2107946144A5087135939 @default.
• W2107946144 hasBestOaLocation W21079461441 @default.
• W2107946144 hasConcept C153911025 @default.
• W2107946144 hasConcept C185592680 @default.
• W2107946144 hasConcept C190283241 @default.
• W2107946144 hasConcept C2776055636 @default.
• W2107946144 hasConcept C2779004061 @default.
• W2107946144 hasConcept C31573885 @default.
• W2107946144 hasConcept C55493867 @default.
• W2107946144 hasConcept C86803240 @default.
• W2107946144 hasConcept C95444343 @default.
• W2107946144 hasConcept C98424977 @default.
• W2107946144 hasConceptScore W2107946144C153911025 @default.
• W2107946144 hasConceptScore W2107946144C185592680 @default.
• W2107946144 hasConceptScore W2107946144C190283241 @default.
• W2107946144 hasConceptScore W2107946144C2776055636 @default.
• W2107946144 hasConceptScore W2107946144C2779004061 @default.
• W2107946144 hasConceptScore W2107946144C31573885 @default.
• W2107946144 hasConceptScore W2107946144C55493867 @default.
• W2107946144 hasConceptScore W2107946144C86803240 @default.
• W2107946144 hasConceptScore W2107946144C95444343 @default.
• W2107946144 hasConceptScore W2107946144C98424977 @default.
• W2107946144 hasIssue "4" @default.
• W2107946144 hasLocation W21079461441 @default.
• W2107946144 hasLocation W21079461442 @default.
• W2107946144 hasLocation W21079461443 @default.
• W2107946144 hasLocation W21079461444 @default.
• W2107946144 hasLocation W21079461445 @default.
• W2107946144 hasOpenAccess W2107946144 @default.

• next