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- W2108074448 abstract "Abstract Objective —To evaluate the use of scintigraphy involving technetium Tc 99m diethylenetriamine pentaacetic acid ( 99m Tc-DTPA) or technetium Tc 99m dimercaptosuccinic acid ( 99m Tc-DMSA) for the determination of kidney morphology and function in green iguanas ( Iguana iguana ). Animals —10 healthy iguanas weighing > 1.6 kg. Procedure —Renal scintigraphy was performed by use of 99m Tc-DTPA in 6 of the iguanas and by use of 99m Tc-DMSA in all 10 iguanas. After the injection of 99m Tc-DMSA, scans were performed for each iguana at intervals during a 20-hour period. Renal biopsies were performed in all 10 iguanas after the final scintigraphic evaluation. Results —In iguanas, the use of 99m Tc-DTPA for renal scintigraphy was nondiagnostic because of serum protein binding and poor renal uptake of the isotope; mean ± SD 99m Tc-DTPA bound to serum proteins was 48.9 ± 9.9%. Renal uptake of 99m Tc-DMSA produced distinct visualization of both kidneys. Renal uptake and soft tissue clearance of 99m Tc-DMSA increased over the 20-hour imaging period; mean ± SD renal uptake of 99m Tc-DMSA was 11.31 ± 3.06% at 20 hours. In each of the 10 iguanas, ultrasonographic and histologic examinations of biopsy specimens from both kidneys revealed no abnormalities. Conclusions and Clinical Relevance —Results indicate that the kidneys of iguanas can be evaluated scintigraphically by use of 99m Tc-DMSA; this technique may be potentially useful for the diagnosis of renal failure in iguanas. ( Am J Vet Res 2005;66:87–92)" @default.
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- W2108074448 title "Evaluation of the use of technetium Tc 99m diethylenetriamine pentaacetic acid and technetium Tc 99m dimercaptosuccinic acid for scintigraphic imaging of the kidneys in green iguanas ( Iguana iguana )" @default.
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- W2108074448 doi "https://doi.org/10.2460/ajvr.2005.66.87" @default.
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