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- W2108105562 abstract "The role of potassium in the progression of cardiovascular disease is complex and controversial. Animal and human data suggest that increases in dietary potassium, decreases in urinary potassium loss, or increases in serum potassium levels through other mechanisms have benefits in several disease states. These include the treatment of hypertension, stroke prevention, arrhythmia prevention, and treatment of congestive heart failure. Recently, the discovery that aldosterone antagonists not only decrease sodium reabsorption and decrease potassium secretion in the nephron, but also decrease pathological injury of such nonepithelial tissues as the myocardium and endothelium, has generated great controversy regarding the actual mechanisms of benefit of these agents. We review the available data and draw conclusions about the relative benefits of modulating potassium balance versus nonrenal effects of aldosterone blockade in patients with cardiovascular disease. The role of potassium in the progression of cardiovascular disease is complex and controversial. Animal and human data suggest that increases in dietary potassium, decreases in urinary potassium loss, or increases in serum potassium levels through other mechanisms have benefits in several disease states. These include the treatment of hypertension, stroke prevention, arrhythmia prevention, and treatment of congestive heart failure. Recently, the discovery that aldosterone antagonists not only decrease sodium reabsorption and decrease potassium secretion in the nephron, but also decrease pathological injury of such nonepithelial tissues as the myocardium and endothelium, has generated great controversy regarding the actual mechanisms of benefit of these agents. We review the available data and draw conclusions about the relative benefits of modulating potassium balance versus nonrenal effects of aldosterone blockade in patients with cardiovascular disease." @default.
- W2108105562 created "2016-06-24" @default.
- W2108105562 creator A5043430229 @default.
- W2108105562 creator A5067577526 @default.
- W2108105562 creator A5081385051 @default.
- W2108105562 date "2005-02-01" @default.
- W2108105562 modified "2023-10-16" @default.
- W2108105562 title "The cardiovascular implications of hypokalemia" @default.
- W2108105562 cites W1546295489 @default.
- W2108105562 cites W1769893219 @default.
- W2108105562 cites W1852223915 @default.
- W2108105562 cites W1909376383 @default.
- W2108105562 cites W1936822231 @default.
- W2108105562 cites W1967943229 @default.
- W2108105562 cites W1968387283 @default.
- W2108105562 cites W1969860470 @default.
- W2108105562 cites W1975399478 @default.
- W2108105562 cites W1988547926 @default.
- W2108105562 cites W1989210780 @default.
- W2108105562 cites W1989722803 @default.
- W2108105562 cites W1994180037 @default.
- W2108105562 cites W1996120650 @default.
- W2108105562 cites W1996984354 @default.
- W2108105562 cites W1997902250 @default.
- W2108105562 cites W2000060059 @default.
- W2108105562 cites W2000392454 @default.
- W2108105562 cites W2002087415 @default.
- W2108105562 cites W2002120276 @default.
- W2108105562 cites W2003514699 @default.
- W2108105562 cites W2004217851 @default.
- W2108105562 cites W2005510151 @default.
- W2108105562 cites W2005862934 @default.
- W2108105562 cites W2007574712 @default.
- W2108105562 cites W2008341839 @default.
- W2108105562 cites W2010641595 @default.
- W2108105562 cites W2011831250 @default.
- W2108105562 cites W2012916945 @default.
- W2108105562 cites W2013154098 @default.
- W2108105562 cites W2016162102 @default.
- W2108105562 cites W2016768719 @default.
- W2108105562 cites W2018227516 @default.
- W2108105562 cites W2020121600 @default.
- W2108105562 cites W2024047808 @default.
- W2108105562 cites W2028960923 @default.
- W2108105562 cites W2029023549 @default.
- W2108105562 cites W2030706533 @default.
- W2108105562 cites W2031626805 @default.
- W2108105562 cites W2032512398 @default.
- W2108105562 cites W2032627401 @default.
- W2108105562 cites W2035349326 @default.
- W2108105562 cites W2035507272 @default.
- W2108105562 cites W2037405672 @default.
- W2108105562 cites W2038498871 @default.
- W2108105562 cites W2039144493 @default.
- W2108105562 cites W2039859816 @default.
- W2108105562 cites W2043277910 @default.
- W2108105562 cites W2050729995 @default.
- W2108105562 cites W2053816472 @default.
- W2108105562 cites W2056734891 @default.
- W2108105562 cites W2057527228 @default.
- W2108105562 cites W2059014716 @default.
- W2108105562 cites W2059919002 @default.
- W2108105562 cites W2060988580 @default.
- W2108105562 cites W2061135005 @default.
- W2108105562 cites W2070629776 @default.
- W2108105562 cites W2072427686 @default.
- W2108105562 cites W2074564417 @default.
- W2108105562 cites W2076118250 @default.
- W2108105562 cites W2080924078 @default.
- W2108105562 cites W2082281095 @default.
- W2108105562 cites W2083033877 @default.
- W2108105562 cites W2087715923 @default.
- W2108105562 cites W2089392247 @default.
- W2108105562 cites W2093009414 @default.
- W2108105562 cites W2094713088 @default.
- W2108105562 cites W2096084342 @default.
- W2108105562 cites W2106374986 @default.
- W2108105562 cites W2106493153 @default.
- W2108105562 cites W2110570357 @default.
- W2108105562 cites W2111945961 @default.
- W2108105562 cites W2112287360 @default.
- W2108105562 cites W2120968620 @default.
- W2108105562 cites W2124370258 @default.
- W2108105562 cites W2126896570 @default.
- W2108105562 cites W2128287943 @default.
- W2108105562 cites W2129079993 @default.
- W2108105562 cites W2133040751 @default.
- W2108105562 cites W2134297068 @default.
- W2108105562 cites W2134589927 @default.
- W2108105562 cites W2135795059 @default.
- W2108105562 cites W2136714451 @default.
- W2108105562 cites W2140739392 @default.
- W2108105562 cites W2141611093 @default.
- W2108105562 cites W2141790142 @default.
- W2108105562 cites W2143358505 @default.
- W2108105562 cites W2144519494 @default.
- W2108105562 cites W2147554218 @default.
- W2108105562 cites W2147737910 @default.