FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108192693> ?p ?o ?g. }

• W2108192693 endingPage "1" @default.
• W2108192693 startingPage "1" @default.
• W2108192693 abstract "The fermentation inhibition of yeast or bacteria by lignocellulose-derived degradation products, during hexose/pentose co-fermentation, is a major bottleneck for cost-effective lignocellulosic biorefineries. To engineer microbial strains for improved performance, it is critical to understand the mechanisms of inhibition that affect fermentative organisms in the presence of major components of a lignocellulosic hydrolysate. The development of a synthetic lignocellulosic hydrolysate (SH) media with a composition similar to the actual biomass hydrolysate will be an important advancement to facilitate these studies. In this work, we characterized the nutrients and plant-derived decomposition products present in AFEX™ pretreated corn stover hydrolysate (ACH). The SH was formulated based on the ACH composition and was further used to evaluate the inhibitory effects of various families of decomposition products during Saccharomyces cerevisiae 424A (LNH-ST) fermentation.The ACH contained high levels of nitrogenous compounds, notably amides, pyrazines, and imidazoles. In contrast, a relatively low content of furans and aromatic and aliphatic acids were found in the ACH. Though most of the families of decomposition products were inhibitory to xylose fermentation, due to their abundance, the nitrogenous compounds showed the most inhibition. From these compounds, amides (products of the ammonolysis reaction) contributed the most to the reduction of the fermentation performance. However, this result is associated to a concentration effect, as the corresponding carboxylic acids (products of hydrolysis) promoted greater inhibition when present at the same molar concentration as the amides. Due to its complexity, the formulated SH did not perfectly match the fermentation profile of the actual hydrolysate, especially the growth curve. However, the SH formulation was effective for studying the inhibitory effect of various compounds on yeast fermentation.The formulation of SHs is an important advancement for future multi-omics studies and for better understanding the mechanisms of fermentation inhibition in lignocellulosic hydrolysates. The SH formulated in this work was instrumental for defining the most important inhibitors in the ACH. Major AFEX decomposition products are less inhibitory to yeast fermentation than the products of dilute acid or steam explosion pretreatments; thus, ACH is readily fermentable by yeast without any detoxification." @default.
• W2108192693 created "2016-06-24" @default.
• W2108192693 creator A5015618811 @default.
• W2108192693 creator A5019907588 @default.
• W2108192693 creator A5026256433 @default.
• W2108192693 creator A5030184764 @default.
• W2108192693 creator A5036217344 @default.
• W2108192693 creator A5043335750 @default.
• W2108192693 creator A5053537762 @default.
• W2108192693 creator A5054369328 @default.
• W2108192693 creator A5075963720 @default.
• W2108192693 date "2015-01-01" @default.
• W2108192693 modified "2023-10-09" @default.
• W2108192693 title "Designer synthetic media for studying microbial-catalyzed biofuel production" @default.
• W2108192693 cites W1616327266 @default.
• W2108192693 cites W1968658600 @default.
• W2108192693 cites W1970351604 @default.
• W2108192693 cites W1970458175 @default.
• W2108192693 cites W1970607902 @default.
• W2108192693 cites W1974049396 @default.
• W2108192693 cites W1982531184 @default.
• W2108192693 cites W2002747229 @default.
• W2108192693 cites W2005291574 @default.
• W2108192693 cites W2012043656 @default.
• W2108192693 cites W2017547171 @default.
• W2108192693 cites W2020507652 @default.
• W2108192693 cites W2021362854 @default.
• W2108192693 cites W2023283652 @default.
• W2108192693 cites W2025900438 @default.
• W2108192693 cites W2054221383 @default.
• W2108192693 cites W2058452807 @default.
• W2108192693 cites W2061543020 @default.
• W2108192693 cites W2062164932 @default.
• W2108192693 cites W2065645659 @default.
• W2108192693 cites W2067916249 @default.
• W2108192693 cites W2076286098 @default.
• W2108192693 cites W2080254779 @default.
• W2108192693 cites W2080820247 @default.
• W2108192693 cites W2084025613 @default.
• W2108192693 cites W2092438050 @default.
• W2108192693 cites W20964975 @default.
• W2108192693 cites W2096845940 @default.
• W2108192693 cites W2099627070 @default.
• W2108192693 cites W2102366182 @default.
• W2108192693 cites W2103802304 @default.
• W2108192693 cites W2105791900 @default.
• W2108192693 cites W2107910846 @default.
• W2108192693 cites W2111870842 @default.
• W2108192693 cites W2113935469 @default.
• W2108192693 cites W2121356177 @default.
• W2108192693 cites W2128200002 @default.
• W2108192693 cites W2139350233 @default.
• W2108192693 cites W2142455741 @default.
• W2108192693 cites W2145235639 @default.
• W2108192693 cites W2155081901 @default.
• W2108192693 cites W2156755411 @default.
• W2108192693 cites W2158718690 @default.
• W2108192693 doi "https://doi.org/10.1186/s13068-014-0179-6" @default.
• W2108192693 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4311453" @default.
• W2108192693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25642283" @default.
• W2108192693 hasPublicationYear "2015" @default.
• W2108192693 type Work @default.
• W2108192693 sameAs 2108192693 @default.
• W2108192693 citedByCount "184" @default.
• W2108192693 countsByYear W21081926932015 @default.
• W2108192693 countsByYear W21081926932016 @default.
• W2108192693 countsByYear W21081926932017 @default.
• W2108192693 countsByYear W21081926932018 @default.
• W2108192693 countsByYear W21081926932019 @default.
• W2108192693 countsByYear W21081926932020 @default.
• W2108192693 countsByYear W21081926932021 @default.
• W2108192693 countsByYear W21081926932022 @default.
• W2108192693 countsByYear W21081926932023 @default.
• W2108192693 crossrefType "journal-article" @default.
• W2108192693 hasAuthorship W2108192693A5015618811 @default.
• W2108192693 hasAuthorship W2108192693A5019907588 @default.
• W2108192693 hasAuthorship W2108192693A5026256433 @default.
• W2108192693 hasAuthorship W2108192693A5030184764 @default.
• W2108192693 hasAuthorship W2108192693A5036217344 @default.
• W2108192693 hasAuthorship W2108192693A5043335750 @default.
• W2108192693 hasAuthorship W2108192693A5053537762 @default.
• W2108192693 hasAuthorship W2108192693A5054369328 @default.
• W2108192693 hasAuthorship W2108192693A5075963720 @default.
• W2108192693 hasBestOaLocation W21081926931 @default.
• W2108192693 hasConcept C100544194 @default.
• W2108192693 hasConcept C115540264 @default.
• W2108192693 hasConcept C150903083 @default.
• W2108192693 hasConcept C185592680 @default.
• W2108192693 hasConcept C2776726243 @default.
• W2108192693 hasConcept C2778234585 @default.
• W2108192693 hasConcept C2779222958 @default.
• W2108192693 hasConcept C2780261296 @default.
• W2108192693 hasConcept C2780294150 @default.
• W2108192693 hasConcept C28800991 @default.
• W2108192693 hasConcept C31903555 @default.
• W2108192693 hasConcept C53991642 @default.
• W2108192693 hasConcept C55493867 @default.
• W2108192693 hasConcept C6557445 @default.

• next