Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108223603> ?p ?o ?g. }
- W2108223603 abstract "The neurobiology of emotion regulation is complex and multifactorial. Current models suggest that connections between information processing by the brain and its communications with the mind and body are impaired by chronic stress and the system is dysregulated in Major Depressive Disorder (MDD). Despite the high prevalence of MDD, the condition remains poorly managed with current treatment approaches, which have traditionally been aimed at correcting a single level of dysfunction, notably in neurotransmitters. A substantial proportion of patients who achieve symptomatic improvement with conventional therapy continue to report residual depressive symptoms and/or poor psychosocialfunctioning. Few clinical trials have been powered to detect changes in measures of functioning, resulting in a lack of evidence-based guidance for clinicians. The present paper reviews the evidence for an integrated, multipronged approach to the management of depression that may involve pharmacotherapy, psychotherapy, Complementary and Alternative Medicine (CAM) approaches such as yoga/meditation, exercise, diet and dietary supplements, and social support groups. The author advocates for the use of a patient-centric approach founded on a strong patientprovider alliance for the management of MDD. A shared decision-making approach should consider the potential role of pharmacotherapy, psychotherapy and CAM, which may enhance symptomatic remission and functional recovery in patients with MDD. These results may be mediated, at least in part, through improved regulation of the Hypothalamic- Pituitary-Adrenal (HPA) axis, and reduced allostatic stress load." @default.
- W2108223603 created "2016-06-24" @default.
- W2108223603 creator A5085599086 @default.
- W2108223603 date "2013-01-01" @default.
- W2108223603 modified "2023-10-16" @default.
- W2108223603 title "Can an Integrative Approach to the Management of Depression Help Patients Achieve Functional Recovery? A Review of Current Literature" @default.
- W2108223603 cites W102171388 @default.
- W2108223603 cites W110083032 @default.
- W2108223603 cites W115137562 @default.
- W2108223603 cites W149611649 @default.
- W2108223603 cites W155479038 @default.
- W2108223603 cites W1606400180 @default.
- W2108223603 cites W1657698983 @default.
- W2108223603 cites W1686749590 @default.
- W2108223603 cites W1746601541 @default.
- W2108223603 cites W1764262054 @default.
- W2108223603 cites W1770079579 @default.
- W2108223603 cites W1799967065 @default.
- W2108223603 cites W1922949753 @default.
- W2108223603 cites W1963535036 @default.
- W2108223603 cites W1964281704 @default.
- W2108223603 cites W1971568036 @default.
- W2108223603 cites W1972276105 @default.
- W2108223603 cites W1974975426 @default.
- W2108223603 cites W1976073163 @default.
- W2108223603 cites W1978315664 @default.
- W2108223603 cites W1979898139 @default.
- W2108223603 cites W1979951312 @default.
- W2108223603 cites W1980261142 @default.
- W2108223603 cites W1980326460 @default.
- W2108223603 cites W1980568154 @default.
- W2108223603 cites W1981220245 @default.
- W2108223603 cites W1981262591 @default.
- W2108223603 cites W1986348607 @default.
- W2108223603 cites W1988763037 @default.
- W2108223603 cites W1989060739 @default.
- W2108223603 cites W1993449216 @default.
- W2108223603 cites W1993849052 @default.
- W2108223603 cites W1996482595 @default.
- W2108223603 cites W2000832866 @default.
- W2108223603 cites W2001281470 @default.
- W2108223603 cites W2002050752 @default.
- W2108223603 cites W2003928890 @default.
- W2108223603 cites W2006406971 @default.
- W2108223603 cites W2014280119 @default.
- W2108223603 cites W2014318238 @default.
- W2108223603 cites W2018504898 @default.
- W2108223603 cites W2019316537 @default.
- W2108223603 cites W2019856631 @default.
- W2108223603 cites W2021025089 @default.
- W2108223603 cites W2025511195 @default.
- W2108223603 cites W2029769026 @default.
- W2108223603 cites W2030380365 @default.
- W2108223603 cites W2031516346 @default.
- W2108223603 cites W2033020443 @default.
- W2108223603 cites W2035297131 @default.
- W2108223603 cites W2037304868 @default.
- W2108223603 cites W2038219475 @default.
- W2108223603 cites W2042033540 @default.
- W2108223603 cites W2042223411 @default.
- W2108223603 cites W2043223939 @default.
- W2108223603 cites W2043480169 @default.
- W2108223603 cites W2047617012 @default.
- W2108223603 cites W2049991997 @default.
- W2108223603 cites W2055569926 @default.
- W2108223603 cites W2055683864 @default.
- W2108223603 cites W2060918456 @default.
- W2108223603 cites W2060923304 @default.
- W2108223603 cites W2061378977 @default.
- W2108223603 cites W2062251052 @default.
- W2108223603 cites W2066231855 @default.
- W2108223603 cites W2070956502 @default.
- W2108223603 cites W2071256705 @default.
- W2108223603 cites W2075511457 @default.
- W2108223603 cites W2076155081 @default.
- W2108223603 cites W2076205788 @default.
- W2108223603 cites W2077871960 @default.
- W2108223603 cites W2078627160 @default.
- W2108223603 cites W2080805505 @default.
- W2108223603 cites W2083048235 @default.
- W2108223603 cites W2083834140 @default.
- W2108223603 cites W2084161052 @default.
- W2108223603 cites W2084266635 @default.
- W2108223603 cites W2088426100 @default.
- W2108223603 cites W2089036448 @default.
- W2108223603 cites W2090816787 @default.
- W2108223603 cites W2091451566 @default.
- W2108223603 cites W2103485312 @default.
- W2108223603 cites W2108337682 @default.
- W2108223603 cites W2110161496 @default.
- W2108223603 cites W2111373412 @default.
- W2108223603 cites W2111637379 @default.
- W2108223603 cites W2113034809 @default.
- W2108223603 cites W2114371710 @default.
- W2108223603 cites W2115531241 @default.
- W2108223603 cites W2115905656 @default.
- W2108223603 cites W2120582212 @default.
- W2108223603 cites W2121878996 @default.
- W2108223603 cites W2121928096 @default.
- W2108223603 cites W2124571614 @default.