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- W2108227340 abstract "The innate recognition of fungal pathogens is mediated by a variety of pattern recognition receptors (PRRs), although much interest has focussed on the Toll-like Receptors (TLR). More recently, however, there is growing appreciation that the non-TLRs have a major role in the control of infection with these organisms. One such molecule is Dectin-1, a C-type lectin-like receptor which induces numerous cellular responses upon recognition of fungal beta-glucans. Here we review our current understanding of the functions of Dectin-1 and the underlying molecular mechanisms, as well as explore the role of this receptor in antifungal immunity." @default.
- W2108227340 created "2016-06-24" @default.
- W2108227340 creator A5001566482 @default.
- W2108227340 creator A5004410792 @default.
- W2108227340 date "2008-01-01" @default.
- W2108227340 modified "2023-10-16" @default.
- W2108227340 title "Dectin-1 and its role in antifungal immunity" @default.
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- W2108227340 doi "https://doi.org/10.1080/13693780802140907" @default.
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