FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108262331> ?p ?o ?g. }

• W2108262331 endingPage "1591" @default.
• W2108262331 startingPage "1585" @default.
• W2108262331 abstract "We investigated the effect of newborn bovine serum on the intracellular calcium [Ca2+]i response of primary cultured bone cells stimulated by fluid flow. As it has been previously established that these cells exhibit [Ca2+]i responses to fluid flow shear stress in saline media without growth factors or other chemically stimulatory factors, we hypothesized that the addition of serum to the flow medium would enhance the mechanosensitivity of the cells. We examined the effect of a short-term (10–15 min) exposure of the cells to 2 and 10% serum prior to flow stimulation (pretreated) compared to not exposing the cells prior to flow stimulation (unpretreated). The cells were subjected to a well-defined, 90-s flow stimulus with shear stress levels ranging from 0.02 to 3.5 Pa in a laminar flow chamber using a saline medium supplemented with 2 or 10% serum. For pretreatment, the serum concentration was the same from pre-flow to flow exposure. We observed a differential effect in the magnitude of the peak [Ca2+]i response modulated by the concentration of serum in the pre-flow medium. Additionally, ATP-supplemented flow was examined as a comparison to the serum-supplemented flow and exhibited a similar trend in the peak [Ca2+]i flow response that was dependent on ATP concentration and pre-flow exposure conditions. These findings demonstrate that under the conditions of this study, chemical agonist exposure can modulate the [Ca2+]i response in bone cells subjected to fluid flow-induced shear stress." @default.
• W2108262331 created "2016-06-24" @default.
• W2108262331 creator A5010048130 @default.
• W2108262331 creator A5043516951 @default.
• W2108262331 creator A5050395062 @default.
• W2108262331 creator A5065410577 @default.
• W2108262331 date "2000-12-01" @default.
• W2108262331 modified "2023-09-27" @default.
• W2108262331 title "Serum modulates the intracellular calcium response of primary cultured bone cells to shear flow" @default.
• W2108262331 cites W1873184289 @default.
• W2108262331 cites W1932241391 @default.
• W2108262331 cites W1964752630 @default.
• W2108262331 cites W1979530095 @default.
• W2108262331 cites W1985167985 @default.
• W2108262331 cites W2006871238 @default.
• W2108262331 cites W2009462543 @default.
• W2108262331 cites W2022793153 @default.
• W2108262331 cites W2035962745 @default.
• W2108262331 cites W2038802014 @default.
• W2108262331 cites W2044658581 @default.
• W2108262331 cites W2048492086 @default.
• W2108262331 cites W2051876520 @default.
• W2108262331 cites W2055407120 @default.
• W2108262331 cites W2077540123 @default.
• W2108262331 cites W2079440796 @default.
• W2108262331 cites W2081278462 @default.
• W2108262331 cites W2083049128 @default.
• W2108262331 cites W2084087342 @default.
• W2108262331 cites W2085417174 @default.
• W2108262331 cites W2085736684 @default.
• W2108262331 cites W2095458341 @default.
• W2108262331 cites W2141260882 @default.
• W2108262331 cites W2144136652 @default.
• W2108262331 cites W2145937652 @default.
• W2108262331 cites W2153057165 @default.
• W2108262331 cites W2155937147 @default.
• W2108262331 cites W2461168023 @default.
• W2108262331 doi "https://doi.org/10.1016/s0021-9290(00)00144-5" @default.
• W2108262331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11006382" @default.
• W2108262331 hasPublicationYear "2000" @default.
• W2108262331 type Work @default.
• W2108262331 sameAs 2108262331 @default.
• W2108262331 citedByCount "50" @default.
• W2108262331 countsByYear W21082623312012 @default.
• W2108262331 countsByYear W21082623312013 @default.
• W2108262331 countsByYear W21082623312014 @default.
• W2108262331 countsByYear W21082623312016 @default.
• W2108262331 countsByYear W21082623312017 @default.
• W2108262331 countsByYear W21082623312021 @default.
• W2108262331 crossrefType "journal-article" @default.
• W2108262331 hasAuthorship W2108262331A5010048130 @default.
• W2108262331 hasAuthorship W2108262331A5043516951 @default.
• W2108262331 hasAuthorship W2108262331A5050395062 @default.
• W2108262331 hasAuthorship W2108262331A5065410577 @default.
• W2108262331 hasConcept C121332964 @default.
• W2108262331 hasConcept C12554922 @default.
• W2108262331 hasConcept C126322002 @default.
• W2108262331 hasConcept C134018914 @default.
• W2108262331 hasConcept C159985019 @default.
• W2108262331 hasConcept C181080969 @default.
• W2108262331 hasConcept C185592680 @default.
• W2108262331 hasConcept C192562407 @default.
• W2108262331 hasConcept C21141959 @default.
• W2108262331 hasConcept C24998067 @default.
• W2108262331 hasConcept C2777397205 @default.
• W2108262331 hasConcept C519063684 @default.
• W2108262331 hasConcept C55493867 @default.
• W2108262331 hasConcept C71924100 @default.
• W2108262331 hasConcept C76563973 @default.
• W2108262331 hasConcept C79879829 @default.
• W2108262331 hasConcept C86803240 @default.
• W2108262331 hasConcept C97355855 @default.
• W2108262331 hasConceptScore W2108262331C121332964 @default.
• W2108262331 hasConceptScore W2108262331C12554922 @default.
• W2108262331 hasConceptScore W2108262331C126322002 @default.
• W2108262331 hasConceptScore W2108262331C134018914 @default.
• W2108262331 hasConceptScore W2108262331C159985019 @default.
• W2108262331 hasConceptScore W2108262331C181080969 @default.
• W2108262331 hasConceptScore W2108262331C185592680 @default.
• W2108262331 hasConceptScore W2108262331C192562407 @default.
• W2108262331 hasConceptScore W2108262331C21141959 @default.
• W2108262331 hasConceptScore W2108262331C24998067 @default.
• W2108262331 hasConceptScore W2108262331C2777397205 @default.
• W2108262331 hasConceptScore W2108262331C519063684 @default.
• W2108262331 hasConceptScore W2108262331C55493867 @default.
• W2108262331 hasConceptScore W2108262331C71924100 @default.
• W2108262331 hasConceptScore W2108262331C76563973 @default.
• W2108262331 hasConceptScore W2108262331C79879829 @default.
• W2108262331 hasConceptScore W2108262331C86803240 @default.
• W2108262331 hasConceptScore W2108262331C97355855 @default.
• W2108262331 hasIssue "12" @default.
• W2108262331 hasLocation W21082623311 @default.
• W2108262331 hasLocation W21082623312 @default.
• W2108262331 hasOpenAccess W2108262331 @default.
• W2108262331 hasPrimaryLocation W21082623311 @default.
• W2108262331 hasRelatedWork W1984619393 @default.
• W2108262331 hasRelatedWork W2003842308 @default.
• W2108262331 hasRelatedWork W202132418 @default.

• next