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• W2108308132 abstract "Yeasts and filamentous fungi are endowed with two different trehalose-hydrolysing activities, termed acid and neutral trehalases according to their optimal pH for enzymatic activity. A wealth of information already exists on fungal neutral trehalases, while data on localization, regulation and function of fungal acid trehalases have remained elusive. The gene encoding the latter enzyme has now been isolated from two yeast species and two filamentous fungi, and sequences encoding putative acid trehalase can be retrieved from available public sequences. Despite weak similarities between amino acids sequences, this type of trehalase potentially harbours either a transmembrane segment or a signal peptide at the N-terminal sequence, as deduced from domain prediction algorithms. This feature, together with the demonstration that acid trehalase from yeasts and filamentous fungi is localized at the cell surface, is consistent with its main role in the utilisation of exogenous trehalose as a carbon source. The growth on this disaccharide is in fact pretty effective in most fungi except in Saccharomyces cerevisiae. This yeast species actually exhibits a ‘Kluyver effect’ on trehalose. Moreover, an oscillatory behaviour reminiscent of what is observed in aerobic glucose-limited continuous cultures at low dilution rate is also observed in batch growth on trehalose. Finally, the S. cerevisiae acid trehalase may also participate in the catabolism of endogenous trehalose by a mechanism that likely requires the export of the disaccharide, its extracellular hydrolysis, and the subsequent uptake of the glucose released. Based on these recent findings, we suggest to rename ‘acid’ and ‘neutral’ trehalases as ‘extracellular’ and ‘cytosolic’ trehalases, which is more adequate to describe their localization and function in the fungal cell." @default.
• W2108308132 created "2016-06-24" @default.
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• W2108308132 date "2005-04-01" @default.
• W2108308132 modified "2023-09-25" @default.
• W2108308132 title "Acid trehalase in yeasts and filamentous fungi: Localization, regulation and physiological function" @default.
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• W2108308132 cites W1519084876 @default.
• W2108308132 cites W1578731554 @default.
• W2108308132 cites W1583200728 @default.
• W2108308132 cites W1607747455 @default.
• W2108308132 cites W1845736521 @default.
• W2108308132 cites W1957827495 @default.
• W2108308132 cites W1966975428 @default.
• W2108308132 cites W1968828966 @default.
• W2108308132 cites W1972353744 @default.
• W2108308132 cites W1977950017 @default.
• W2108308132 cites W1978909753 @default.
• W2108308132 cites W1979096574 @default.
• W2108308132 cites W1986343331 @default.
• W2108308132 cites W1987021757 @default.
• W2108308132 cites W1992397700 @default.
• W2108308132 cites W1999412919 @default.
• W2108308132 cites W2008203775 @default.
• W2108308132 cites W2008961852 @default.
• W2108308132 cites W2014847553 @default.
• W2108308132 cites W2017087434 @default.
• W2108308132 cites W2021664197 @default.
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• W2108308132 cites W2033053971 @default.
• W2108308132 cites W2041481661 @default.
• W2108308132 cites W2045850300 @default.
• W2108308132 cites W2048946374 @default.
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• W2108308132 cites W2071252308 @default.
• W2108308132 cites W2072440127 @default.
• W2108308132 cites W2073414410 @default.
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• W2108308132 cites W2137683543 @default.
• W2108308132 cites W2140455347 @default.
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• W2108308132 doi "https://doi.org/10.1016/j.femsyr.2005.01.002" @default.
• W2108308132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15780651" @default.
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