FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108321458> ?p ?o ?g. }

• W2108321458 endingPage "1690.e1" @default.
• W2108321458 startingPage "1680" @default.
• W2108321458 abstract "Nonselective β blockers (NSBBs) reduce portal pressure and the risk for variceal hemorrhage in patients with cirrhosis. However, development of spontaneous bacterial peritonitis (SBP) in these patients could preclude treatment with NSBBs because of their effects on the circulatory reserve. We investigated the effects of NSBBs in patients with cirrhosis and ascites with and without SBP.We performed a retrospective analysis of data from 607 consecutive patients with cirrhosis who had their first paracentesis at the Medical University of Vienna from 2006 through 2011. Cox models were calculated to investigate the effect of NSBBs on transplant-free survival time and adjusted for Child-Pugh stage and presence of varices.NSBBs increased transplant-free survival in patients without SBP (hazard ratio = 0.75; 95% confidence interval: 0.581-0.968; P = .027) and reduced days of nonelective hospitalization (19.4 days/year for patients on NSBBs vs 23.9 days/year for patients not taking NSBBs). NSBBs had only moderate effects on systemic hemodynamics at patients' first paracentesis. However, at the first diagnosis of SBP, the proportion of hemodynamically compromised patients with systolic arterial pressure <100 mm Hg was higher among those who received NSBBs (38% vs 18% of those not taking NSBBs; P = .002), as was the proportion of patients with arterial pressure <82 mm Hg (64% of those taking NSBBs vs 44% of those not taking NSBBs; P = .006). Among patients with SBP, NSBBs reduced transplant-free survival (hazard ratio = 1.58; 95% confidence interval: 1.098-2.274; P = .014) and increased days of nonelective hospitalization (29.6 days/person-year in patients on NSBBs vs 23.7 days/person-year in those not taking NSBBs). A higher proportion of patients on NSBBs had hepatorenal syndrome (24% vs 11% in those not taking NSBBs; P = .027) and grade C acute kidney injury (20% vs 8% for those not taking NSBBs; P = .021).Among patients with cirrhosis and SBP, NSBBs increase the proportion who are hemodynamically compromised, time of hospitalization, and risks for hepatorenal syndrome and acute kidney injury. They also reduce transplant-free survival. Patients with cirrhosis and SBP should not receive NSBBs." @default.
• W2108321458 created "2016-06-24" @default.
• W2108321458 creator A5017952403 @default.
• W2108321458 creator A5018983251 @default.
• W2108321458 creator A5030421035 @default.
• W2108321458 creator A5030477696 @default.
• W2108321458 creator A5036486301 @default.
• W2108321458 creator A5040507331 @default.
• W2108321458 creator A5046244856 @default.
• W2108321458 creator A5062137762 @default.
• W2108321458 creator A5068098596 @default.
• W2108321458 creator A5073880705 @default.
• W2108321458 creator A5078132520 @default.
• W2108321458 creator A5087316703 @default.
• W2108321458 creator A5088941698 @default.
• W2108321458 date "2014-06-01" @default.
• W2108321458 modified "2023-10-17" @default.
• W2108321458 title "Nonselective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients With Cirrhosis and Spontaneous Bacterial Peritonitis" @default.
• W2108321458 cites W1228830179 @default.
• W2108321458 cites W1855579400 @default.
• W2108321458 cites W1963554573 @default.
• W2108321458 cites W1964051982 @default.
• W2108321458 cites W1965709993 @default.
• W2108321458 cites W1966583064 @default.
• W2108321458 cites W1967300023 @default.
• W2108321458 cites W1994589471 @default.
• W2108321458 cites W1994974867 @default.
• W2108321458 cites W1995649092 @default.
• W2108321458 cites W2006041438 @default.
• W2108321458 cites W2006916640 @default.
• W2108321458 cites W2008860610 @default.
• W2108321458 cites W2017557941 @default.
• W2108321458 cites W2020757210 @default.
• W2108321458 cites W2032323546 @default.
• W2108321458 cites W2035042251 @default.
• W2108321458 cites W2047239918 @default.
• W2108321458 cites W2048954476 @default.
• W2108321458 cites W2056453370 @default.
• W2108321458 cites W2062363596 @default.
• W2108321458 cites W2065178093 @default.
• W2108321458 cites W2068633232 @default.
• W2108321458 cites W2072478284 @default.
• W2108321458 cites W2079748214 @default.
• W2108321458 cites W2083181466 @default.
• W2108321458 cites W2111820868 @default.
• W2108321458 cites W2136034922 @default.
• W2108321458 cites W2148609006 @default.
• W2108321458 cites W2149266696 @default.
• W2108321458 cites W2153643268 @default.
• W2108321458 cites W2156259187 @default.
• W2108321458 cites W2158454416 @default.
• W2108321458 cites W2166467296 @default.
• W2108321458 cites W2170056055 @default.
• W2108321458 cites W2171716651 @default.
• W2108321458 cites W2334200094 @default.
• W2108321458 cites W27517105 @default.
• W2108321458 cites W3115875733 @default.
• W2108321458 doi "https://doi.org/10.1053/j.gastro.2014.03.005" @default.
• W2108321458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24631577" @default.
• W2108321458 hasPublicationYear "2014" @default.
• W2108321458 type Work @default.
• W2108321458 sameAs 2108321458 @default.
• W2108321458 citedByCount "320" @default.
• W2108321458 countsByYear W21083214582014 @default.
• W2108321458 countsByYear W21083214582015 @default.
• W2108321458 countsByYear W21083214582016 @default.
• W2108321458 countsByYear W21083214582017 @default.
• W2108321458 countsByYear W21083214582018 @default.
• W2108321458 countsByYear W21083214582019 @default.
• W2108321458 countsByYear W21083214582020 @default.
• W2108321458 countsByYear W21083214582021 @default.
• W2108321458 countsByYear W21083214582022 @default.
• W2108321458 countsByYear W21083214582023 @default.
• W2108321458 crossrefType "journal-article" @default.
• W2108321458 hasAuthorship W2108321458A5017952403 @default.
• W2108321458 hasAuthorship W2108321458A5018983251 @default.
• W2108321458 hasAuthorship W2108321458A5030421035 @default.
• W2108321458 hasAuthorship W2108321458A5030477696 @default.
• W2108321458 hasAuthorship W2108321458A5036486301 @default.
• W2108321458 hasAuthorship W2108321458A5040507331 @default.
• W2108321458 hasAuthorship W2108321458A5046244856 @default.
• W2108321458 hasAuthorship W2108321458A5062137762 @default.
• W2108321458 hasAuthorship W2108321458A5068098596 @default.
• W2108321458 hasAuthorship W2108321458A5073880705 @default.
• W2108321458 hasAuthorship W2108321458A5078132520 @default.
• W2108321458 hasAuthorship W2108321458A5087316703 @default.
• W2108321458 hasAuthorship W2108321458A5088941698 @default.
• W2108321458 hasConcept C126322002 @default.
• W2108321458 hasConcept C141071460 @default.
• W2108321458 hasConcept C207103383 @default.
• W2108321458 hasConcept C2776258039 @default.
• W2108321458 hasConcept C2776988256 @default.
• W2108321458 hasConcept C2777214474 @default.
• W2108321458 hasConcept C2777364826 @default.
• W2108321458 hasConcept C2778808290 @default.
• W2108321458 hasConcept C2779065481 @default.
• W2108321458 hasConcept C2780496750 @default.
• W2108321458 hasConcept C44249647 @default.

• next