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- W2108336514 endingPage "239" @default.
- W2108336514 startingPage "209" @default.
- W2108336514 abstract "▪ Abstract Crawling cells of various morphologies displace themselves in their biological environments by a similar overall mechanism of protrusion through actin assembly at the front coordinated with retraction at the rear. Different cell types organize very distinct protruding structures, yet they do so through conserved biochemical mechanisms to regulate actin polymerization dynamics and vary the mechanical properties of these structures. The moving cell must spatially and temporally regulate the biochemical interactions of its protein components to exert control over higher-order dynamic structures created by these proteins and global cellular responses four or more orders of magnitude larger in scale and longer in time than the individual protein-protein interactions that comprise them. To fulfill its biological role, a cell globally responds with high sensitivity to a local perturbation or signal and coordinates its many intracellular actin-based functional structures with the physical environment it experiences to produce directed movement. This review attempts to codify some unifying principles for cell motility that span organizational scales from single protein polymer filaments to whole crawling cells." @default.
- W2108336514 created "2016-06-24" @default.
- W2108336514 creator A5050426581 @default.
- W2108336514 creator A5078436996 @default.
- W2108336514 date "2004-06-01" @default.
- W2108336514 modified "2023-09-30" @default.
- W2108336514 title "Crawling Toward a Unified Model of Cell Motility: Spatial and Temporal Regulation of Actin Dynamics" @default.
- W2108336514 cites W1486817521 @default.
- W2108336514 cites W1496078104 @default.
- W2108336514 cites W1508246694 @default.
- W2108336514 cites W1565036272 @default.
- W2108336514 cites W1569063010 @default.
- W2108336514 cites W1593929303 @default.
- W2108336514 cites W1605957976 @default.
- W2108336514 cites W1626382598 @default.
- W2108336514 cites W1857350744 @default.
- W2108336514 cites W1859722076 @default.
- W2108336514 cites W1952185161 @default.
- W2108336514 cites W1964419797 @default.
- W2108336514 cites W1964678604 @default.
- W2108336514 cites W1966975175 @default.
- W2108336514 cites W1972229751 @default.
- W2108336514 cites W1973512372 @default.
- W2108336514 cites W1977874542 @default.
- W2108336514 cites W1978525637 @default.
- W2108336514 cites W1979126290 @default.
- W2108336514 cites W1984732269 @default.
- W2108336514 cites W1985719686 @default.
- W2108336514 cites W1986606329 @default.
- W2108336514 cites W1992835639 @default.
- W2108336514 cites W1993016783 @default.
- W2108336514 cites W1994571520 @default.
- W2108336514 cites W1997339395 @default.
- W2108336514 cites W1997472077 @default.
- W2108336514 cites W1997778687 @default.
- W2108336514 cites W1999920891 @default.
- W2108336514 cites W2001839227 @default.
- W2108336514 cites W2002208582 @default.
- W2108336514 cites W2003468593 @default.
- W2108336514 cites W2010568463 @default.
- W2108336514 cites W2010955080 @default.
- W2108336514 cites W2012915205 @default.
- W2108336514 cites W2015982738 @default.
- W2108336514 cites W2019267260 @default.
- W2108336514 cites W2020081859 @default.
- W2108336514 cites W2023410605 @default.
- W2108336514 cites W2026173674 @default.
- W2108336514 cites W2027949267 @default.
- W2108336514 cites W2028640392 @default.
- W2108336514 cites W2029189987 @default.
- W2108336514 cites W2031952383 @default.
- W2108336514 cites W2032100189 @default.
- W2108336514 cites W2032363819 @default.
- W2108336514 cites W2034728705 @default.
- W2108336514 cites W2037726485 @default.
- W2108336514 cites W2038049928 @default.
- W2108336514 cites W2038088851 @default.
- W2108336514 cites W2039325880 @default.
- W2108336514 cites W2039701501 @default.
- W2108336514 cites W2039727443 @default.
- W2108336514 cites W2040893843 @default.
- W2108336514 cites W2041915841 @default.
- W2108336514 cites W2045621376 @default.
- W2108336514 cites W2045923054 @default.
- W2108336514 cites W2047886675 @default.
- W2108336514 cites W2049750865 @default.
- W2108336514 cites W2050277545 @default.
- W2108336514 cites W2053429769 @default.
- W2108336514 cites W2053431375 @default.
- W2108336514 cites W2053911894 @default.
- W2108336514 cites W2053994471 @default.
- W2108336514 cites W2054639242 @default.
- W2108336514 cites W2056370235 @default.
- W2108336514 cites W2056954673 @default.
- W2108336514 cites W2060872711 @default.
- W2108336514 cites W2062941196 @default.
- W2108336514 cites W2067340834 @default.
- W2108336514 cites W2067917704 @default.
- W2108336514 cites W2068092779 @default.
- W2108336514 cites W2068684349 @default.
- W2108336514 cites W2070852036 @default.
- W2108336514 cites W2070992372 @default.
- W2108336514 cites W2071156082 @default.
- W2108336514 cites W2071442472 @default.
- W2108336514 cites W2074622507 @default.
- W2108336514 cites W2075336591 @default.
- W2108336514 cites W2077353456 @default.
- W2108336514 cites W2078306077 @default.
- W2108336514 cites W2079244641 @default.
- W2108336514 cites W2086884747 @default.
- W2108336514 cites W2088662752 @default.
- W2108336514 cites W2093741736 @default.
- W2108336514 cites W2094874279 @default.
- W2108336514 cites W2096791952 @default.
- W2108336514 cites W2099158550 @default.
- W2108336514 cites W2099847661 @default.
- W2108336514 cites W2100181443 @default.
- W2108336514 cites W2100324155 @default.