FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108356735> ?p ?o ?g. }

• W2108356735 endingPage "576" @default.
• W2108356735 startingPage "572" @default.
• W2108356735 abstract "1. The effects of 1,4-dihydropyridine calcium antagonists with different biological half-lives, amlodipine and nifedipine retard on 24 h blood pressure (BP), heart rate (HR) and autonomic nerve activity in patients with essential hypertension were compared. 2. Twenty patients (six men and 14 women; mean (+/- SEM) age 63 +/- 2 years) with essential hypertension were enrolled in the present study. Their ambulatory BP and electrocardiograms were monitored for 24 h at intervals of 30 min with a portable recorder after a 4 week drug-free period, after a 4 week treatment period with amlodipine (2.5 or 5 mg once daily) and after a 4 week treatment period with nifedipine retard (10 or 20 mg twice daily). The order of the three periods was randomized. Autonomic nerve activity was evaluated by power spectral analysis of HR variability, using the high frequency (HF) component as an index of parasympathetic activity and the ratio of the low frequency (LF) to the HF component as an index of sympathovagal balance. 3. Amlodipine and nifedipine retard significantly lowered the 24 h BP to a similar extent (amlodipine: -12.7 +/- 2.6/-5.6 +/- 1.4 mmHg, P < 0.01/P < 0.01; nifedipine retard: -15.1 +/- 2.1/-6.9 +/- 1.5 mmHg, P < 0.01/P < 0.01). Amlodipine did not change the 24 h average HR, while nifedipine retard significantly increased it (+3.3 +/- 1.2 b.p.m., P < 0.05). Amlodipine also did not change the HF component or the ratio of the LF to the HF component. However, nifedipine retard significantly decreased the HF component (P < 0.01) and increased the ratio of the LF to the HF component (P < 0.05). 4. These results suggest that nifedipine retard caused a decrease in parasympathetic activity and an increase in sympathetic activity with reflex tachycardia in these patients with essential hypertension, while amlodipine did not produce such effects on the autonomic nervous system." @default.
• W2108356735 created "2016-06-24" @default.
• W2108356735 creator A5021763876 @default.
• W2108356735 creator A5057681787 @default.
• W2108356735 creator A5061549158 @default.
• W2108356735 creator A5063030973 @default.
• W2108356735 date "1998-08-01" @default.
• W2108356735 modified "2023-10-16" @default.
• W2108356735 title "EFFECTS OF AMLODIPINE AND NIFEDIPINE RETARD ON AUTONOMIC NERVE ACTIVITY IN HYPERTENSIVE PATIENTS" @default.
• W2108356735 cites W1968096578 @default.
• W2108356735 cites W1969838275 @default.
• W2108356735 cites W1975594270 @default.
• W2108356735 cites W1976926964 @default.
• W2108356735 cites W1986765615 @default.
• W2108356735 cites W1992945980 @default.
• W2108356735 cites W1996528326 @default.
• W2108356735 cites W1997791597 @default.
• W2108356735 cites W2003593457 @default.
• W2108356735 cites W2011765859 @default.
• W2108356735 cites W2032619089 @default.
• W2108356735 cites W2039542922 @default.
• W2108356735 cites W2059629032 @default.
• W2108356735 cites W2060356482 @default.
• W2108356735 cites W2062618262 @default.
• W2108356735 cites W2070434001 @default.
• W2108356735 cites W2077886785 @default.
• W2108356735 cites W2078584337 @default.
• W2108356735 cites W2092805838 @default.
• W2108356735 cites W2102043873 @default.
• W2108356735 cites W2106073810 @default.
• W2108356735 cites W2153638346 @default.
• W2108356735 cites W2158741046 @default.
• W2108356735 cites W2166089332 @default.
• W2108356735 cites W2172117134 @default.
• W2108356735 cites W2285072859 @default.
• W2108356735 cites W2318480619 @default.
• W2108356735 cites W2727581825 @default.
• W2108356735 cites W4231250029 @default.
• W2108356735 cites W4294159793 @default.
• W2108356735 cites W4301857746 @default.
• W2108356735 doi "https://doi.org/10.1111/j.1440-1681.1998.tb02254.x" @default.
• W2108356735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9673431" @default.
• W2108356735 hasPublicationYear "1998" @default.
• W2108356735 type Work @default.
• W2108356735 sameAs 2108356735 @default.
• W2108356735 citedByCount "33" @default.
• W2108356735 countsByYear W21083567352012 @default.
• W2108356735 countsByYear W21083567352013 @default.
• W2108356735 countsByYear W21083567352014 @default.
• W2108356735 countsByYear W21083567352015 @default.
• W2108356735 countsByYear W21083567352016 @default.
• W2108356735 crossrefType "journal-article" @default.
• W2108356735 hasAuthorship W2108356735A5021763876 @default.
• W2108356735 hasAuthorship W2108356735A5057681787 @default.
• W2108356735 hasAuthorship W2108356735A5061549158 @default.
• W2108356735 hasAuthorship W2108356735A5063030973 @default.
• W2108356735 hasConcept C126322002 @default.
• W2108356735 hasConcept C164705383 @default.
• W2108356735 hasConcept C2777097880 @default.
• W2108356735 hasConcept C2777953023 @default.
• W2108356735 hasConcept C2779066535 @default.
• W2108356735 hasConcept C2779646130 @default.
• W2108356735 hasConcept C2779740467 @default.
• W2108356735 hasConcept C2781212610 @default.
• W2108356735 hasConcept C35785553 @default.
• W2108356735 hasConcept C42219234 @default.
• W2108356735 hasConcept C519063684 @default.
• W2108356735 hasConcept C71924100 @default.
• W2108356735 hasConcept C84393581 @default.
• W2108356735 hasConceptScore W2108356735C126322002 @default.
• W2108356735 hasConceptScore W2108356735C164705383 @default.
• W2108356735 hasConceptScore W2108356735C2777097880 @default.
• W2108356735 hasConceptScore W2108356735C2777953023 @default.
• W2108356735 hasConceptScore W2108356735C2779066535 @default.
• W2108356735 hasConceptScore W2108356735C2779646130 @default.
• W2108356735 hasConceptScore W2108356735C2779740467 @default.
• W2108356735 hasConceptScore W2108356735C2781212610 @default.
• W2108356735 hasConceptScore W2108356735C35785553 @default.
• W2108356735 hasConceptScore W2108356735C42219234 @default.
• W2108356735 hasConceptScore W2108356735C519063684 @default.
• W2108356735 hasConceptScore W2108356735C71924100 @default.
• W2108356735 hasConceptScore W2108356735C84393581 @default.
• W2108356735 hasIssue "7-8" @default.
• W2108356735 hasLocation W21083567351 @default.
• W2108356735 hasLocation W21083567352 @default.
• W2108356735 hasOpenAccess W2108356735 @default.
• W2108356735 hasPrimaryLocation W21083567351 @default.
• W2108356735 hasRelatedWork W136460646 @default.
• W2108356735 hasRelatedWork W1968228317 @default.
• W2108356735 hasRelatedWork W2018353516 @default.
• W2108356735 hasRelatedWork W2108356735 @default.
• W2108356735 hasRelatedWork W2113821080 @default.
• W2108356735 hasRelatedWork W2353156659 @default.
• W2108356735 hasRelatedWork W2370240998 @default.
• W2108356735 hasRelatedWork W2394469040 @default.
• W2108356735 hasRelatedWork W2395640815 @default.
• W2108356735 hasRelatedWork W2431920331 @default.
• W2108356735 hasVolume "25" @default.

• next