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- W2108367044 abstract "The prepregnancy body mass index (BMI, kg/m2) is one of the few modifiable risk factors for preterm birth (PTB). The objective of this study was to determine the relationship between WHO categories of BMI and spontaneous preterm birth (SPTB). From our perinatal database (2005 - 2010), we analyzed data on 11,967 women who delivered singleton births after excluding women who had a medically indicated PTB or delivered < 20 weeks. SPTB was defined as a PTB resulting from PPROM or spontaneous preterm labor. We used the WHO international classification of BMI (see figure). We analyzed the data using univariable and multivariable logistic regression analysis, adjusting for maternal age, race/ethnicity, parity, cigarette smoking, history of PTB, chronic medical disease, uterine anomalies, cervical incompetence and infertility. SPTB accounted for 65% of all PTBs. The incidence of SPTB was highest among women who had severe or moderate thinness, 28% and 22%, respectively. Compared to women with normal range BMI, the categories significantly associated with an increased risk of SPTB were: severe thinness (AOR = 2.7, 95% CI = 1.3 to 5.8, P = 0.01) and moderate thinness (AOR = 2.1, 95% CI 1.3 to 3.5, P = 0.003). We also found that obese class I was associated with a decreased risk (AOR = 0.75, 95% CI = 0.60 to 0.93, P = 0.01). Women with BMI < 17 are more than twice as likely to have SPTB compared to women with normal range BMI. Because severe and moderate thinness prior to pregnancy is potentially modifiable, interventions for women in these categories to achieve a healthy preconception weight should be evaluated." @default.
- W2108367044 created "2016-06-24" @default.
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- W2108367044 date "2013-01-01" @default.
- W2108367044 modified "2023-10-16" @default.
- W2108367044 title "520: Severe and moderate thinness (prepregnancy body mass index <17) as risk factors for spontaneous preterm birth" @default.
- W2108367044 doi "https://doi.org/10.1016/j.ajog.2012.10.686" @default.
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