FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108394907> ?p ?o ?g. }

• W2108394907 endingPage "511" @default.
• W2108394907 startingPage "505" @default.
• W2108394907 abstract "To evaluate the toxicity and efficacy of a modified deGramont regimen of 5-fluorouracil (5-FU), leucovorin, and oxaliplatin in patients with advanced colorectal cancer who have progressed on at least one but not more than two prior chemotherapy regimens.Patients with stage 4 colorectal cancer were treated with oxaliplatin 85 mg/m2 by a 2-hour intravenous infusion, followed by leucovorin 500 mg/m2 by a 2-hour intravenous infusion, followed by 5-FU 400 mg/m2 by bolus injection, followed by 5-FU 2.4 g/m2 administered by a 46-hour continuous infusion. Cycles were administered every 2 weeks.Seventy patients were treated and 68 patients had previously received irinotecan. Eleven percent of patients had a partial response, 33% of CEA-evaluable patients had a > or = 50% drop in their CEA level. The median time to progression was 6.2 months, and the median overall survival was 8.7 months. Toxicity was mild to moderate, as 14% of patients experienced grade 3 or 4 neutropenia and 3% of patients experienced grade 3 neuropathy.The modified deGramont regimen of 5-FU, leucovorin, and oxaliplatin is tolerable and is associated with a modest degree of antitumor activity in patients who have progressed on both 5-FU and irinotecan." @default.
• W2108394907 created "2016-06-24" @default.
• W2108394907 creator A5002447665 @default.
• W2108394907 creator A5017947396 @default.
• W2108394907 creator A5026505060 @default.
• W2108394907 creator A5049314303 @default.
• W2108394907 creator A5055389521 @default.
• W2108394907 creator A5066315785 @default.
• W2108394907 creator A5070720153 @default.
• W2108394907 creator A5075051023 @default.
• W2108394907 creator A5088474933 @default.
• W2108394907 creator A5090604653 @default.
• W2108394907 date "2003-01-01" @default.
• W2108394907 modified "2023-10-16" @default.
• W2108394907 title "A Phase II Study of Modified deGramont 5-Fluorouracil, Leucovorin, and Oxaliplatin in Previously Treated Patients with Metastatic Colorectal Cancer" @default.
• W2108394907 cites W1912318374 @default.
• W2108394907 cites W2006824814 @default.
• W2108394907 cites W2007615142 @default.
• W2108394907 cites W2032146688 @default.
• W2108394907 cites W2033465919 @default.
• W2108394907 cites W2059972525 @default.
• W2108394907 cites W2090025081 @default.
• W2108394907 cites W2096122707 @default.
• W2108394907 cites W2121368761 @default.
• W2108394907 cites W2125387113 @default.
• W2108394907 cites W2128447158 @default.
• W2108394907 cites W2134112440 @default.
• W2108394907 cites W2162313061 @default.
• W2108394907 cites W2229860171 @default.
• W2108394907 cites W2240214496 @default.
• W2108394907 cites W2314927739 @default.
• W2108394907 cites W4246299175 @default.
• W2108394907 doi "https://doi.org/10.1081/cnv-120022359" @default.
• W2108394907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14533439" @default.
• W2108394907 hasPublicationYear "2003" @default.
• W2108394907 type Work @default.
• W2108394907 sameAs 2108394907 @default.
• W2108394907 citedByCount "6" @default.
• W2108394907 crossrefType "journal-article" @default.
• W2108394907 hasAuthorship W2108394907A5002447665 @default.
• W2108394907 hasAuthorship W2108394907A5017947396 @default.
• W2108394907 hasAuthorship W2108394907A5026505060 @default.
• W2108394907 hasAuthorship W2108394907A5049314303 @default.
• W2108394907 hasAuthorship W2108394907A5055389521 @default.
• W2108394907 hasAuthorship W2108394907A5066315785 @default.
• W2108394907 hasAuthorship W2108394907A5070720153 @default.
• W2108394907 hasAuthorship W2108394907A5075051023 @default.
• W2108394907 hasAuthorship W2108394907A5088474933 @default.
• W2108394907 hasAuthorship W2108394907A5090604653 @default.
• W2108394907 hasConcept C121608353 @default.
• W2108394907 hasConcept C126322002 @default.
• W2108394907 hasConcept C141071460 @default.
• W2108394907 hasConcept C2776694085 @default.
• W2108394907 hasConcept C2777063308 @default.
• W2108394907 hasConcept C2780259306 @default.
• W2108394907 hasConcept C2780456651 @default.
• W2108394907 hasConcept C2780962732 @default.
• W2108394907 hasConcept C2781413609 @default.
• W2108394907 hasConcept C29730261 @default.
• W2108394907 hasConcept C31760486 @default.
• W2108394907 hasConcept C43376680 @default.
• W2108394907 hasConcept C526805850 @default.
• W2108394907 hasConcept C71924100 @default.
• W2108394907 hasConcept C90924648 @default.
• W2108394907 hasConceptScore W2108394907C121608353 @default.
• W2108394907 hasConceptScore W2108394907C126322002 @default.
• W2108394907 hasConceptScore W2108394907C141071460 @default.
• W2108394907 hasConceptScore W2108394907C2776694085 @default.
• W2108394907 hasConceptScore W2108394907C2777063308 @default.
• W2108394907 hasConceptScore W2108394907C2780259306 @default.
• W2108394907 hasConceptScore W2108394907C2780456651 @default.
• W2108394907 hasConceptScore W2108394907C2780962732 @default.
• W2108394907 hasConceptScore W2108394907C2781413609 @default.
• W2108394907 hasConceptScore W2108394907C29730261 @default.
• W2108394907 hasConceptScore W2108394907C31760486 @default.
• W2108394907 hasConceptScore W2108394907C43376680 @default.
• W2108394907 hasConceptScore W2108394907C526805850 @default.
• W2108394907 hasConceptScore W2108394907C71924100 @default.
• W2108394907 hasConceptScore W2108394907C90924648 @default.
• W2108394907 hasIssue "4" @default.
• W2108394907 hasLocation W21083949071 @default.
• W2108394907 hasLocation W21083949072 @default.
• W2108394907 hasOpenAccess W2108394907 @default.
• W2108394907 hasPrimaryLocation W21083949071 @default.
• W2108394907 hasRelatedWork W1912318374 @default.
• W2108394907 hasRelatedWork W2027936171 @default.
• W2108394907 hasRelatedWork W2032188922 @default.
• W2108394907 hasRelatedWork W2052181765 @default.
• W2108394907 hasRelatedWork W2072176886 @default.
• W2108394907 hasRelatedWork W2108394907 @default.
• W2108394907 hasRelatedWork W2111606472 @default.
• W2108394907 hasRelatedWork W2111837783 @default.
• W2108394907 hasRelatedWork W2112727687 @default.
• W2108394907 hasRelatedWork W2164906123 @default.
• W2108394907 hasVolume "21" @default.
• W2108394907 isParatext "false" @default.
• W2108394907 isRetracted "false" @default.
• W2108394907 magId "2108394907" @default.

• next