FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108429043> ?p ?o ?g. }

• W2108429043 endingPage "2862" @default.
• W2108429043 startingPage "2857" @default.
• W2108429043 abstract "Pseudomonas aeruginosa is one of the most important opportunistic pathogens involved in nosocomial infections, cystic fibrosis patients included. Hospital isolates frequently present multidrug-resistance (MDR) phenotypes as the consequence of constant antibiotic selective pressure. The kinetics of emergence of P. aeruginosa MDR mutants under antibiotic selective pressure indicated that long-term incubation in the presence of the bacteriostatic antibiotic tetracycline increases the mutation rate per cell per day of P. aeruginosa PAO1 by several orders of magnitude. The tetracycline-resistant mutants obtained were stable, showed decreased susceptibility to antibiotics belonging to different structural families, and contained an outer-membrane protein not present in the wild-type P. aeruginosa strain PAO1. These data are consistent with the hypothesis that incubation in the presence of tetracycline favours the emergence of MDR mutants in P. aeruginosa. The results are relevant for understanding the rapid emergence of antibiotic-resistant mutants among bacterial populations during infections. Their relationship to other models of increased mutagenesis under stress is discussed with respect to the adaptive mutation phenomenon." @default.
• W2108429043 created "2016-06-24" @default.
• W2108429043 creator A5060958743 @default.
• W2108429043 creator A5083627238 @default.
• W2108429043 creator A5087607394 @default.
• W2108429043 date "1999-10-01" @default.
• W2108429043 modified "2023-10-03" @default.
• W2108429043 title "Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa" @default.
• W2108429043 cites W130764347 @default.
• W2108429043 cites W1501170769 @default.
• W2108429043 cites W1564690891 @default.
• W2108429043 cites W1832974928 @default.
• W2108429043 cites W1848355102 @default.
• W2108429043 cites W1878232800 @default.
• W2108429043 cites W1967842571 @default.
• W2108429043 cites W1974134043 @default.
• W2108429043 cites W1998132713 @default.
• W2108429043 cites W2007889243 @default.
• W2108429043 cites W2020988366 @default.
• W2108429043 cites W2026049706 @default.
• W2108429043 cites W2042167030 @default.
• W2108429043 cites W2043698490 @default.
• W2108429043 cites W2072774078 @default.
• W2108429043 cites W2078785671 @default.
• W2108429043 cites W2082914266 @default.
• W2108429043 cites W2085164535 @default.
• W2108429043 cites W2091015559 @default.
• W2108429043 cites W2091265903 @default.
• W2108429043 cites W2098167270 @default.
• W2108429043 cites W2099982440 @default.
• W2108429043 cites W2103872347 @default.
• W2108429043 cites W2124392784 @default.
• W2108429043 cites W2125391335 @default.
• W2108429043 cites W2127588278 @default.
• W2108429043 cites W2133279754 @default.
• W2108429043 cites W2135064031 @default.
• W2108429043 cites W2146288504 @default.
• W2108429043 cites W2154414887 @default.
• W2108429043 cites W2159680005 @default.
• W2108429043 cites W2166628294 @default.
• W2108429043 cites W2169380146 @default.
• W2108429043 cites W4375842955 @default.
• W2108429043 cites W56353252 @default.
• W2108429043 doi "https://doi.org/10.1099/00221287-145-10-2857" @default.
• W2108429043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10537207" @default.
• W2108429043 hasPublicationYear "1999" @default.
• W2108429043 type Work @default.
• W2108429043 sameAs 2108429043 @default.
• W2108429043 citedByCount "103" @default.
• W2108429043 countsByYear W21084290432012 @default.
• W2108429043 countsByYear W21084290432013 @default.
• W2108429043 countsByYear W21084290432014 @default.
• W2108429043 countsByYear W21084290432015 @default.
• W2108429043 countsByYear W21084290432016 @default.
• W2108429043 countsByYear W21084290432017 @default.
• W2108429043 countsByYear W21084290432018 @default.
• W2108429043 countsByYear W21084290432019 @default.
• W2108429043 countsByYear W21084290432020 @default.
• W2108429043 countsByYear W21084290432021 @default.
• W2108429043 countsByYear W21084290432022 @default.
• W2108429043 countsByYear W21084290432023 @default.
• W2108429043 crossrefType "journal-article" @default.
• W2108429043 hasAuthorship W2108429043A5060958743 @default.
• W2108429043 hasAuthorship W2108429043A5083627238 @default.
• W2108429043 hasAuthorship W2108429043A5087607394 @default.
• W2108429043 hasBestOaLocation W21084290431 @default.
• W2108429043 hasConcept C104317684 @default.
• W2108429043 hasConcept C133936738 @default.
• W2108429043 hasConcept C136622501 @default.
• W2108429043 hasConcept C143065580 @default.
• W2108429043 hasConcept C16318435 @default.
• W2108429043 hasConcept C2777637488 @default.
• W2108429043 hasConcept C2780923616 @default.
• W2108429043 hasConcept C501593827 @default.
• W2108429043 hasConcept C501734568 @default.
• W2108429043 hasConcept C523546767 @default.
• W2108429043 hasConcept C54355233 @default.
• W2108429043 hasConcept C58123911 @default.
• W2108429043 hasConcept C86803240 @default.
• W2108429043 hasConcept C89423630 @default.
• W2108429043 hasConcept C94665300 @default.
• W2108429043 hasConceptScore W2108429043C104317684 @default.
• W2108429043 hasConceptScore W2108429043C133936738 @default.
• W2108429043 hasConceptScore W2108429043C136622501 @default.
• W2108429043 hasConceptScore W2108429043C143065580 @default.
• W2108429043 hasConceptScore W2108429043C16318435 @default.
• W2108429043 hasConceptScore W2108429043C2777637488 @default.
• W2108429043 hasConceptScore W2108429043C2780923616 @default.
• W2108429043 hasConceptScore W2108429043C501593827 @default.
• W2108429043 hasConceptScore W2108429043C501734568 @default.
• W2108429043 hasConceptScore W2108429043C523546767 @default.
• W2108429043 hasConceptScore W2108429043C54355233 @default.
• W2108429043 hasConceptScore W2108429043C58123911 @default.
• W2108429043 hasConceptScore W2108429043C86803240 @default.
• W2108429043 hasConceptScore W2108429043C89423630 @default.
• W2108429043 hasConceptScore W2108429043C94665300 @default.
• W2108429043 hasIssue "10" @default.
• W2108429043 hasLocation W21084290431 @default.

• next